Epidemiology of cytomegalovirus Infection among mothers and infants in Colombia

Details

• Alternative Title:
  J Med Virol
• Personal Author:
  Rico, Angelica ; Dollard, Sheila C. ; Valencia, Diana ; Corchuelo, Sheryll ; Tong, Van T. ; Laiton-Donato, Katherine ; Amin, Minal M. ; Benavides, Monica ; Wong, Phili ; Newton, Suzanne ; Daza, Marcela ; Cates, Jordan ; Gonzalez, Maritza ; Zambrano, Laura D. ; Mercado, Marcela M. ; Ailes, Elizabeth C. ; Rodriguez, Helena M. ; Gilboa, Suzanne M. ; Acosta, Jacqueline ; Ricaldi, Jessica ; Pelaez, Dioselina ; Honein, Margaret A. ; Ospina, Martha L. ; Lanzieri, Tatiana M.
• Description:
  We assessed maternal and infant cytomegalovirus (CMV) infection in Colombia. Maternal serum was tested for CMV immunoglobulin G antibodies at a median of 10 (interquartile range: 8-12) weeks gestation (n = 1501). CMV DNA polymerase chain reaction was performed on infant urine to diagnose congenital (≤21 days of life) and postnatal (>21 days) infection. Maternal CMV seroprevalence was 98.1% (95% confidence interval [CI]: 97.5%-98.8%). Congenital CMV prevalence was 8.4 (95% CI: 3.9%-18.3%; 6/711) per 1000 live births. Among 472 infants without confirmed congenital CMV infection subsequently tested at age 6 months, 258 (54.7%, 95% CI: 50.2%-59.1%) had postnatal infection.
• Subjects:
  Article CMV Colombia Congenital Infection Cytomegalovirus Newborns Postnatal Infection Prevalence Seroprevalence
• Source:
  J Med Virol. 93(11):6393-6397
• Pubmed ID:
  33475162
• Pubmed Central ID:
  PMC8292416
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Place as Subject:
  Colombia
• Volume:
  93
• Issue:
  11
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:b3b6d6a8eb80cd3ffea99568fb39b8a8be254354f35718a56782fb083d201578
• Download URL:
  https://stacks.cdc.gov/view/cdc/110256/cdc_110256_DS1.pdf
• File Type:
  [PDF - 355.98 KB ]