Predictors of Nonseroconversion after SARS-CoV-2 Infection

Liu, Weimin; Russell, Ronnie M.; Bibollet-Ruche, Frederic; Skelly, Ashwin N.; Sherrill-Mix, Scott; Freeman, Drew A.; Stoltz, Regina; Lindemuth, Emily; Lee, Fang-Hua; Sterrett, Sarah; Bar, Katharine J.; Erdmann, Nathaniel; Gouma, Sigrid; Hensley, Scott E.; Ketas, Thomas; Cupo, Albert; Cruz Portillo, Victor M.; Moore, John P.; Bieniasz, Paul D.; Hatziioannou, Theodora; Massey, Greer; Minyard, Mary-Beth; Saag, Michael S.; Davis, Randall S.; Shaw, George M.; Britt, William J.; Leal, Sixto M.; Goepfert, Paul; Hahn, Beatrice H.

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Predictors of Nonseroconversion after SARS-CoV-2 Infection

September 2021
By Liu, Weimin ; Russell, Ronnie M. ; Bibollet-Ruche, Frederic ; ...
Source: Emerg Infect Dis. 27(9):2454-2458

[PDF-1.39 MB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Liu, Weimin ; Russell, Ronnie M. ; Bibollet-Ruche, Frederic ; Skelly, Ashwin N. ; Sherrill-Mix, Scott ; ... More +

Liu, Weimin ; Russell, Ronnie M. ; Bibollet-Ruche, Frederic ; Skelly, Ashwin N. ; Sherrill-Mix, Scott ; Freeman, Drew A. ; Stoltz, Regina ; Lindemuth, Emily ; Lee, Fang-Hua ; Sterrett, Sarah ; Bar, Katharine J. ; Erdmann, Nathaniel ; Gouma, Sigrid ; Hensley, Scott E. ; Ketas, Thomas ; Cupo, Albert ; Cruz Portillo, Victor M. ; Moore, John P. ; Bieniasz, Paul D. ; Hatziioannou, Theodora ; Massey, Greer ; Minyard, Mary-Beth ; Saag, Michael S. ; Davis, Randall S. ; Shaw, George M. ; Britt, William J. ; Leal, Sixto M. ; Goepfert, Paul ; Hahn, Beatrice H. Less -
Description:

Not all persons recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop SARS-CoV-2-specific antibodies. We show that nonseroconversion is associated with younger age and higher reverse transcription PCR cycle threshold values and identify SARS-CoV-2 viral loads in the nasopharynx as a major correlate of the systemic antibody response.
Subjects:

[+]

Antibody Formation Coronavirus Infections Covid-19 Covid-19 Serological Testing Humans Nasopharynx Sars-Cov-2 Seroconversion
Source:

Emerg Infect Dis. 27(9):2454-2458
Pubmed ID:

34193339
Pubmed Central ID:

PMC8386781
Document Type:

Journal Article
Funding:

R37 AI150590/AI/NIAID NIH HHSUnited States/ ; T32 GM007170/GM/NIGMS NIH HHSUnited States/ ; R01 AI110553/AI/NIAID NIH HHSUnited States/ ; U19 AI082630/AI/NIAID NIH HHSUnited States/ ; R01 AI050529/AI/NIAID NIH HHSUnited States/ ; ... More +

R37 AI150590/AI/NIAID NIH HHSUnited States/ ; T32 GM007170/GM/NIGMS NIH HHSUnited States/ ; R01 AI110553/AI/NIAID NIH HHSUnited States/ ; U19 AI082630/AI/NIAID NIH HHSUnited States/ ; R01 AI050529/AI/NIAID NIH HHSUnited States/ ; P01 AI110657/AI/NIAID NIH HHSUnited States/ ; P30 AI045008/AI/NIAID NIH HHSUnited States/ ; R01 AI036082/AI/NIAID NIH HHSUnited States/ Less -
Volume:

27
Issue:

9
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:1327c26805ffff9d54d37904a8adc0e8418d40249fa356f5a6a9b4e4010c8bdd
Download URL:

https://stacks.cdc.gov/view/cdc/109722/cdc_109722_DS1.pdf
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