Trends in the use of active surveillance and treatments in Medicare beneficiaries diagnosed with localized prostate cancer

Details

• Alternative Title:
  Urol Oncol
• Personal Author:
  Liu, Yu ; Hall, Ingrid J. ; Filson, Christopher ; Howard, David H.
• Description:
  Background:
  
  The treatment for men diagnosed with localized prostate cancer has changed over time given the increased attention to the harms associated with over-diagnosis and the development of protocols for active surveillance.
  
  Methods:
  
  We examined trends in the treatment of men diagnosed with localized prostate cancer between 2004 and 2015, using the most recently available data from Surveillance, Epidemiology, and End Results Program (SEER)-Medicare. Patients were stratified by Gleason score, age, and race groups.
  
  Results:
  
  The use of active surveillance increased from 22% in 2004–2005 to 50% in 2014–2015 for patients with a Gleason score of 6 or below and increased from 9% in 2004–2005 to 13% in 2014–2015 for patients with a Gleason score of 7 or above. Patients with a Gleason score of 7 or above had increased use of intensity-modulated radiation therapy and prostatectomy, especially among patients aged 75 years and older. Among patients with a Gleason score of 6 or below non-Hispanic black men were less likely to undergo active surveillance than non-Hispanic white men.
  
  Conclusions:
  
  There has been a large increase in the use of active surveillance among men with a Gleason score of 6 or below. However, non-Hispanic black men with a Gleason score of 6 or below are less likely to receive active surveillance.
  
  
• Subjects:
  Aged Humans Male Medicare Neoplasm Grading Prostatic Neoplasms Retrospective Studies United States Watchful Waiting
• Keywords:
  Active Surveillance Buprenorphine Methadone Mortality Naltrexone New Treatment Methods Prostate Cancer Treatment Treatment Disparities Treatment Trends
• Source:
  Urol Oncol. 39(7):432.e1-432.e10
• Pubmed ID:
  33308973
• Pubmed Central ID:
  PMC8374746
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  39
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:11aa51bcfd5df97c23a20521da274c6a0cfc4ef9d246d8e8b88befa9d61b9152c2fde26c79ba9f896ae8bf21fd88389b0b11d4924e4d3687ddcd65075f9edf81
• Download URL:
  https://stacks.cdc.gov/view/cdc/109330/cdc_109330_DS1.pdf
• File Type:
  [PDF - 1.23 MB ]