Transmission Dynamics of Severe Acute Respiratory Syndrome Coronavirus 2 in High-Density Settings, Minnesota, USA, March–June 2020

Details

• Alternative Title:
  Emerg Infect Dis
• Journal Article:
  Emerging Infectious Diseases
• Personal Author:
  Bernu, Carmen ; Carter, Rosalind ; Como-Sabetti, Kathryn ; Danila, Richard ; Ehresmann, Kris ; Eikmeier, Dana ; Garfin, Jacob ; Honein, Margaret A. ; Lehnertz, Nicholas B. ; Lynfield, Ruth ; MacCannell, Duncan ; Martin, Karen ; Medus, Carlota ; Plumb, Matthew ; Pung, Kelly ; Smith, Kirk E. ; Taylor, Joanne ; VonBank, Brittany ; Wang, Xiong ; Wiedinmyer, Brooke ; Zipprich, Jennifer
• Description:
  Coronavirus disease has disproportionately affected persons in congregate settings and high-density workplaces. To determine more about the transmission patterns of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in these settings, we performed whole-genome sequencing and phylogenetic analysis on 319 (14.4%) samples from 2,222 SARS-CoV-2-positive persons associated with 8 outbreaks in Minnesota, USA, during March-June 2020. Sequencing indicated that virus spread in 3 long-term care facilities and 2 correctional facilities was associated with a single genetic sequence and that in a fourth long-term care facility, outbreak cases were associated with 2 distinct sequences. In contrast, cases associated with outbreaks in 2 meat-processing plants were associated with multiple SARS-CoV-2 sequences. These results suggest that a single introduction of SARS-CoV-2 into a facility can result in a widespread outbreak. Early identification and cohorting (segregating) of virus-positive persons in these settings, along with continued vigilance with infection prevention and control measures, is imperative. [Description provided by NIOSH]
• Subjects:
  Communicable Diseases Coronavirus Infections COVID-19 Disease Outbreaks Occupational Exposure Occupational Health Pandemics Safety
• Keywords:
  Coronavirus; COVID-19; SARS-CoV-2; Infectious diseases; Disease transmission; Occupational exposure
• Source:
  Emerg Infect Dis 2021 Aug; 27(8):2052-2063
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  1080-6040
• Pubmed ID:
  34138695
• Pubmed Central ID:
  PMC8314815
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; Minnesota ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Diseases & Conditions ; Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  12 pdf pages
• Volume:
  27
• Issue:
  8
• NIOSHTIC Number:
  nn:20070757
• Contact Point Address:
  Nicholas B. Lehnertz, Minnesota Department of Health, 625 Robert St N, St. Paul, MN 55164, USA
• Federal Fiscal Year:
  2021
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Performing Organization:
  University of Minnesota
• Peer Reviewed:
  True
• Collection(s):
  Emerging Infectious Diseases National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0610ca4eb206a80a8ec9b87445ccaaaf60680e32937a1f1ea5e9a54630c19d9ffadc3530734565e28701df6abebc3a0826b3a472e10d2bfc1894672adec6137d
• Download URL:
  https://stacks.cdc.gov/view/cdc/108789/cdc_108789_DS1.pdf
• File Type:
  [PDF - 3.83 MB ]