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Laboratory Techniques for Identifying Causes of Allergic Dermatitis
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Aug 2021
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Source: Immunol Allergy Clin North Am. 41(3):423-438
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Alternative Title:Immunol Allergy Clin North Am
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Personal Author:
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Description:This article reviews the laboratory's role in identifying causes of chemical-induced allergic dermatitis. Several topics will be discussed. Allergen hazard identification refers to testing of chemicals for their sensitization potential. Animal-based, in silico, in chemico, and in vitro tests have been developed to identify the skin sensitization hazard of potential chemical allergens, but only a few of these are accepted by regulatory agencies. Laboratory investigations have also evaluated the stability of several commercially available allergic contact dermatitis patch tests. Such studies are considered product testing and are usually conducted in analytical chemistry laboratories.
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Pubmed ID:34225898
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Pubmed Central ID:PMC8324072
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Volume:41
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Issue:3
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