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Reactivity measurement in estimation of benzoquinone and benzoquinone derivatives’ allergenicity

CITE Title : Reactivity measurement in estimation of benzoquinone and benzoquinone derivatives’ allergenicity Personal Author(s) : Mbiya, Wilbes;Chipinda, Itai;Simoyi, Reuben H.;Siegel, Paul D.; Published Date : Dec 02 2015 Source : Toxicology. 339:34-39. URL : https://stacks.cdc.gov/view/cdc/37621 Mbiya, Wilbes et al. (2015). Reactivity measurement in estimation of benzoquinone and benzoquinone derivatives’ allergenicity. 339 Mbiya, Wilbes et al. "Reactivity measurement in estimation of benzoquinone and benzoquinone derivatives’ allergenicity" 339 (2015) Mbiya, Wilbes et al. "Reactivity measurement in estimation of benzoquinone and benzoquinone derivatives’ allergenicity" vol. 339, 2015 Export RIS Citation Information.

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Mbiya, Wilbes ;

Chipinda, Itai

Dec 02 2015 | Toxicology. 339:34-39.

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Benzoquinone (BQ) and benzoquinone derivatives (BQD) are used in the production of dyes and cosmetics. While BQ, an extreme skin sensitizer, is an ele...
Laboratory Techniques for Identifying Causes of Allergic Dermatitis

CITE Title : Laboratory Techniques for Identifying Causes of Allergic Dermatitis Personal Author(s) : Chipinda, Itai;Anderson, Stacey E.;Siegel, Paul D.; Published Date : Aug 2021 Source : Immunol Allergy Clin North Am. 41(3):423-438 URL : https://stacks.cdc.gov/view/cdc/108517 Chipinda, Itai et al. (2021). Laboratory Techniques for Identifying Causes of Allergic Dermatitis. 41(3). Chipinda, Itai and Anderson, Stacey E. and Siegel, Paul D. "Laboratory Techniques for Identifying Causes of Allergic Dermatitis" 41, no. 3 (2021) Chipinda, Itai et al. "Laboratory Techniques for Identifying Causes of Allergic Dermatitis" vol. 41, no. 3, 2021 Export RIS Citation Information.

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Chipinda, Itai ;

Anderson, Stacey E.

Aug 2021 | Immunol Allergy Clin North Am. 41(3):423-438

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This article reviews the laboratory's role in identifying causes of chemical-induced allergic dermatitis. Several topics will be discussed. Allergen h...
Pyridoxylamine reactivity kinetics as an amine based nucleophile for screening electrophilic dermal sensitizers

CITE Title : Pyridoxylamine reactivity kinetics as an amine based nucleophile for screening electrophilic dermal sensitizers Personal Author(s) : Chipinda, Itai;Mbiya, Wilbes;Adigun, Risikat Ajibola;Morakinyo, Moshood K.;Law, Brandon F.;Simoyi, Reuben H.;Siegel, Paul D.; Published Date : Dec 12 2013 Source : Toxicology. 315:102-109. URL : https://stacks.cdc.gov/view/cdc/34746 Chipinda, Itai et al. (2013). Pyridoxylamine reactivity kinetics as an amine based nucleophile for screening electrophilic dermal sensitizers. 315 Chipinda, Itai et al. "Pyridoxylamine reactivity kinetics as an amine based nucleophile for screening electrophilic dermal sensitizers" 315 (2013) Chipinda, Itai et al. "Pyridoxylamine reactivity kinetics as an amine based nucleophile for screening electrophilic dermal sensitizers" vol. 315, 2013 Export RIS Citation Information.

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Chipinda, Itai ;

Mbiya, Wilbes

Dec 12 2013 | Toxicology. 315:102-109.

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Chemical allergens bind directly, or after metabolic or abiotic activation, to endogenous proteins to become allergenic. Assessment of this initial bi...
Detailed mechanistic investigation into the S-nitrosation of cysteamine

CITE Title : Detailed mechanistic investigation into the S-nitrosation of cysteamine Personal Author(s) : Morakinyo, Moshood K.;Chipinda, Itai;Hettick, Justin;Siegel, Paul D.;Abramson, Jonathan;Strongin, Robert;Martincigh, Bice S.;Simoyi, Reuben H.; Published Date : 2012 Source : Can J Chem. 9(9):724-738. URL : https://stacks.cdc.gov/view/cdc/36206 Morakinyo, Moshood K. et al. (2012). Detailed mechanistic investigation into the S-nitrosation of cysteamine. 9(9). Morakinyo, Moshood K. et al. "Detailed mechanistic investigation into the S-nitrosation of cysteamine" 9, no. 9 (2012) Morakinyo, Moshood K. et al. "Detailed mechanistic investigation into the S-nitrosation of cysteamine" vol. 9, no. 9, 2012 Export RIS Citation Information.

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Morakinyo, Moshood K. ;

Chipinda, Itai

2012 | Can J Chem. 9(9):724-738.

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The nitrosation of cysteamine (H2NCH2CH2SH) to produce cysteamine-S-nitrosothiol (CANO) was studied in slightly acidic medium by using nitrous acid pr...
Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin

CITE Title : Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin Personal Author(s) : Mhike, Morgen;Hettick, Justin M.;Chipinda, Itai;Law, Brandon F.;Bledsoe, Toni A.;Lemons, Angela R.;Nayak, Ajay P.;Green, Brett J.;Beezhold, Donald H.;Simoyi, Reuben H.;Siegel, Paul D.; Published Date : Feb 04 2016 Source : J Immunol Methods. 431:38-44. URL : https://stacks.cdc.gov/view/cdc/38493 Mhike, Morgen et al. (2016). Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin. 431 Mhike, Morgen et al. "Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin" 431 (2016) Mhike, Morgen et al. "Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin" vol. 431, 2016 Export RIS Citation Information.

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Mhike, Morgen ;

Hettick, Justin M.

Feb 04 2016 | J Immunol Methods. 431:38-44.

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Diisocyanates (dNCOs) are low molecular weight chemical sensitizers that react with autologous proteins to produce neoantigens. dNCO-haptenated protei...
Haptenation: Chemical Reactivity and Protein Binding

CITE Title : Haptenation: Chemical Reactivity and Protein Binding Personal Author(s) : Chipinda, Itai;Hettick, Justin M.;Siegel, Paul D.; Published Date : Jun 30 2011 Source : J Allergy (Cairo). 2011; 2011. URL : https://stacks.cdc.gov/view/cdc/4029 Chipinda, Itai et al. (2011). Haptenation: Chemical Reactivity and Protein Binding. 2011 Chipinda, Itai and Hettick, Justin M. and Siegel, Paul D. "Haptenation: Chemical Reactivity and Protein Binding" 2011 (2011) Chipinda, Itai et al. "Haptenation: Chemical Reactivity and Protein Binding" vol. 2011, 2011 Export RIS Citation Information.

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Chipinda, Itai ;

Hettick, Justin M.

Jun 30 2011 | J Allergy (Cairo). 2011; 2011.

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Low molecular weight chemical (LMW) allergens are commonly referred to as haptens. Haptens must complex with proteins to be recognized by the immune s...