Details:

Corporate Authors:
National Center for Immunization and Respiratory Diseases (U.S.). Division of Viral Diseases.
Description:
Last updated July 27, 2021

Key Points

• All COVID-19 vaccines currently authorized in the United States are effective against COVID-19, including serious outcomes of severe disease, hospitalization, and death.

• Available evidence suggests the currently authorized mRNA COVID-19 vaccines (Pfizer-BioNTech and Moderna) are highly effective against hospitalization and death for a variety of strains, including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), and Delta (B.1.617.2); data suggest lower effectiveness against confirmed infection and symptomatic disease caused by the Beta, Gamma, and Delta variants compared with the ancestral strain and Alpha variant. Ongoing monitoring of vaccine effectiveness against variants is needed.

• A growing body of evidence indicates that people fully vaccinated with an mRNA vaccine (Pfizer-BioNTech or Moderna) are less likely than unvaccinated persons to acquire SARS-CoV-2 or to transmit it to others. However, the risk for SARS-CoV-2 breakthrough infection in fully vaccinated people cannot be completely eliminated as long as there is continued community transmission of the virus.

• Studies are underway to learn more about the effectiveness of Johnson & Johnson/Janssen vaccine.

• At this time, there are limited data on vaccine effectiveness in people who are immunocompromised. People with immunocompromising conditions, including those taking immunosuppressive medications, should discuss the need for personal protective measures after vaccination with their healthcare provider.

• This updated science brief synthesizes the scientific evidence supporting CDC’s guidance for fully vaccinated people and will continue to be updated as more information becomes available.


Content Notes:
Key points -- Background -- COVID-19 vaccine efficacy and effectiveness -- Emerging SARS-CoV-2 viral variants and vaccine performance -- Conclusions.
Subjects:
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Coronavirus Infections/prevention & Control COVID-19 Vaccines COVID-19/prevention & Control Vaccination Viral Vaccines
Series:
Science brief
Document Type:
Webpage
Place as Subject:
United States
Collection(s):
Stephen B. Thacker CDC Library collection
Main Document Checksum:
[+]
urn:sha256:11155a3f04b2909f36e1b97e6d75481c3c4a08c38c7a09a4d1b4292fbc22b802
Download URL:
https://stacks.cdc.gov/view/cdc/108354/cdc_108354_DS1.pdf
File Type:

Supporting Files

• fully-vaccinated-people.html

  htm

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