Depression and survival in head and neck cancer patients

Details

• Alternative Title:
  Oral Oncol
• Personal Author:
  Rieke, Katherine ; Schmid, Kendra K. ; Lydiatt, William ; Houfek, Julia ; Boilesen, Eugene ; Watanabe-Galloway, Shinobu
• Description:
  Objective:
  
  Though depression often afflicts head and neck cancer (HNC) patients, few studies have examined the association between depression and survival in this particular cancer population. The objective of this study is to investigate the five-year survival of HNC patients by depression status.
  
  Materials and methods:
  
  This study used SEER-Medicare data from 2002–2010 and identified depression diagnosis two years before and one year after cancer diagnosis. HNC patients were identified using ICD-O3 codes and depression was identified using ICD-9-CM codes from Medicare claims.
  
  Results:
  
  Of the 3466 patients included in the study, 642 (18.5%) were diagnosed with depression during the study period. Compared to those who received no depression diagnosis, those diagnosed with depression prior to cancer or after cancer diagnosis were more likely to die of cancer (HR = 1.49; 95% CI = 1.27, 1.76 and HR = 1.38; 95% CI = 1.16, 1.65, respectively). Similarly, when looking at death from any cause, those diagnosed with depression prior to cancer diagnosis and those who received a diagnosis of depression after cancer were more likely to die from any death compared to those without depression (HR= 1.55; 95% CI = 1.36, 1.76 and HR = 1.40; 95% CI = 1.21, 1.62, respectively).
  
  Conclusions:
  
  The results emphasize the need for early identification and treatment of depression in HNC patients, as well as the establishment of policies to routinely screen these patients throughout the cancer treatment process.
  
  
• Subjects:
  Aged Aged, 80 And Over Article Cancer Depression Epidemiology Head And Neck Cancer Head And Neck Neoplasms Humans Oncology SEER-Medicare SEER Program Survival

  More +
• Source:
  Oral Oncol. 65:76-82
• Pubmed ID:
  28109472
• Pubmed Central ID:
  PMC8201663
• Document Type:
  Journal Article
• Funding:
  R25 CA112383/CA/NCI NIH HHS/United States ; HHSN261201000140C/CA/NCI NIH HHS/United States ; HHSN261201000035C/CA/NCI NIH HHS/United States ; HHSN261201000035I/CA/NCI NIH HHS/United States ; HHSN261201000034C/CA/NCI NIH HHS/United States ; U58 DP003862/DP/NCCDPHP CDC HHS/United States
• Volume:
  65
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:2e11fb012576c1bf73874a2cff219dcce3e553939fbb1ea077678379fc83a23a
• Download URL:
  https://stacks.cdc.gov/view/cdc/107357/cdc_107357_DS1.pdf
• File Type:
  [PDF - 103.44 KB ]