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Association of Urinary Phenols with Increased Body Weight Measures and Obesity in Children and Adolescents
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10 2014
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Source: J Pediatr. 165(4):744-749
[PDF-327.51 KB]
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Alternative Title:J Pediatr
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Description:Objective
To examine the association of urinary levels of the environmental phenol pesticides 2,5-dichlorophenol, 2,4-dichlorophenol, and triclosan with body weight outcomes in children and adolescent participants in the National Health and Nutrition Examination Survey 2007-2010.
Study design
We performed multivariate linear and multinomial logistic regressions to analyze the association of body mass index (BMI) z-score, waist circumference (WC), and obesity with urinary pesticide concentration in children and adolescents.
Results
After adjustment for covariates, we found a statistically significant positive association (P < .05) between both 2,5-dichlorophenol and 2,4-dichlorophenol with BMI z-score, WC, and obesity in children and adolescents. After stratification by age, the significant associations remained only in adolescents (ages 12-19). No associations were found between triclosan and any of the body weight outcomes.
Conclusions
We found an association between dichlorophenols and increased body weight measures (BMI z-score, WC, and obesity) in adolescents. However, further studies, such as a longitudinal study, are needed to confirm and elucidate on our findings.
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Pubmed ID:25063718
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Pubmed Central ID:PMC8114784
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Volume:165
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Issue:4
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