Identification of and Surveillance for the SARS-CoV-2 Variants B.1.427 and B.1.429 — Colorado, January–March 2021

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Martin Webb, Lindsey ; Matzinger, Shannon ; Grano, Christopher ; Kawasaki, Breanna ; Stringer, Ginger ; Bankers, Laura ; Herlihy, Rachel
• Description:
  The B.1.427 and B.1.429 Variantss of SARS-CoV-2, the Virus that causes COVID-19, were first described in Southern California on January 20, 2021 (1); on March 16 they were designated Variantss of concern* (2). Data on these Variantss are limited, but initial reports suggest that, compared with other lineages, they might be more infectious (1,2), cause more severe illness (2), and be less susceptible to neutralizing monoclonal antibody products such as bamlanivimab, an investigational treatment for mild-to-moderate COVID-19 (1-3). On January 24, the Colorado Department of Public Health and Environment (CDPHE) identified the first Colorado case of COVID-19 attributed to these Variantss. B.1.427 and B.1.429 were considered a single Variants described as CAL.20C or B.1.427/B.1.429 in the 20C clade (1,3); in this report "B.1.427/B.1.429" refers to B.1.427 or B.1.429 lineage, including those reported as B.1.427/B.1.429 without further differentiation.
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Child Child, Preschool CoronaVirus Infections COVID-19 COVID-19 Nucleic Acid Testing Female Humans Infant Male Middle Aged Public Health Surveillance SARS-CoV-2 Young Adult

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• Source:
  MMWR Morbidity Mortal Weekly Rep. 70(19):717-718
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  33988184
• Pubmed Central ID:
  PMC8118155
• Document Type:
  Journal Article
• Place as Subject:
  Colorado
• Pages in Document:
  2 pdf pages
• Volume:
  70
• Issue:
  19
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:dd6986f5c5fbced2c30d46d0382a13dd3c20c37a4722c9ec5e19d885fa129e91edf94299fa338821deaff7d9ecdf9159676fd89612401e5abf7d10d4e7144040
• Download URL:
  https://stacks.cdc.gov/view/cdc/106670/cdc_106670_DS1.pdf
• File Type:
  [PDF - 125.45 KB ]