i
Use of Genomics to Track Coronavirus Disease Outbreaks, New Zealand
-
2021
-
-
Source: Emerg Infect Dis. 27(5):1317-1322
[PDF-3.66 MB]
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:Real-time genomic sequencing has played a major role in tracking the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), contributing greatly to disease mitigation strategies. In August 2020, after having eliminated the virus, New Zealand experienced a second outbreak. During that outbreak, New Zealand used genomic sequencing in a primary role, leading to a second elimination of the virus. We generated genomes from 78% of the laboratory-confirmed samples of SARS-CoV-2 from the second outbreak and compared them with the available global genomic data. Genomic sequencing rapidly identified that virus causing the second outbreak in New Zealand belonged to a single cluster, thus resulting from a single introduction. However, successful identification of the origin of this outbreak was impeded by substantial biases and gaps in global sequencing data. Access to a broader and more heterogenous sample of global genomic data would strengthen efforts to locate the source of any new outbreaks.
-
Subjects:
-
Source:
-
Pubmed ID:33900175
-
Pubmed Central ID:PMC8084492
-
Document Type:
-
Place as Subject:
-
Location:
-
Volume:27
-
Issue:5
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
