Incidence and Trends of the Leading Cancers with Elevated Incidence Among American Indian and Alaska Native Populations, 2012–2016

Details

• Alternative Title:
  Am J Epidemiol
• Personal Author:
  Melkonian, Stephanie C. ; Weir, Hannah K. ; Jim, Melissa A. ; Preikschat, Bailey ; Haverkamp, Donald ; White, Mary C.
• Description:
  Cancer incidence varies among American Indian and Alaska Native (AI/AN) populations, as well as between AI/AN and White populations. This study examined trends for cancers with elevated incidence among AI/AN compared with non-Hispanic White populations and estimated potentially avoidable incident cases among AI/AN populations. Incident cases diagnosed during 2012-2016 were identified from population-based cancer registries and linked with the Indian Health Service patient registration databases to improve racial classification of AI/AN populations. Age-adjusted rates (per 100,000) and trends were calculated for cancers with elevated incidence among AI/AN compared with non-Hispanic White populations (rate ratio of >1.0) according to region. Trends were estimated using joinpoint regression analyses. Expected cancers were estimated by applying age-specific cancer incidence rates among non-Hispanic White populations to population estimates for AI/AN populations. Excess cancer cases among AI/AN populations were defined as observed minus expected cases. Liver, stomach, kidney, lung, colorectal, and female breast cancers had higher incidence rates among AI/AN populations across most regions. Between 2012 and 2016, nearly 5,200 excess cancers were diagnosed among AI/AN populations, with the largest number of excess cancers (1,925) occurring in the Southern Plains region. Culturally informed efforts could reduce cancer disparities associated with these and other cancers among AI/AN populations.
• Subjects:
  Adult Aged Alaska Natives Female Humans Incidence Indians, North American Male Middle Aged Neoplasms Population Surveillance Registries Retrospective Studies

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• Source:
  Am J Epidemiol. 190(4):528-538
• Pubmed ID:
  33506248
• Pubmed Central ID:
  PMC8026484
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Place as Subject:
  United States
• Volume:
  190
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:dc7febea85ca70b6a7c2776f6a76d69327cd5a850edd7938e66eb33f959e2c05
• Download URL:
  https://stacks.cdc.gov/view/cdc/105638/cdc_105638_DS1.pdf
• File Type:
  [PDF - 407.26 KB ]