First Identified Cases of SARS-CoV-2 Variant P.1 in the U.S. — Minnesota, January 2021

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Firestone, Melanie J. ; Lorentz, Alexandra J. ; Meyer, Stephanie ; Wang,, Xiong ; Como-Sabetti, Kathryn ; Vetter, Sara ; Smith,, Kirk ; Holzbauer, Stacy ; Beaudoin, Amanda ; Garfin, Jacob ; Ehresmann, Kristin ; Danila, Richard ; Lynfield, Ruth
• Description:
  Since December 2020, the Minnesota Department of Health (MDH) Public Health Laboratory has been receiving 100 specimens per week (50 from each of two clinical partners) with low cycle threshold (Ct) values for routine Surveillance for SARS-CoV-2, the Virus that causes COVID-19. On January 25, 2021, MDH identified the SARS-CoV-2 Variants P.1 in one specimen through this Surveillance system using whole genome sequencing, representing the first identified case of this Variants in the U.S. The P.1 Variants was first identified in travelers from Brazil during routine airport screening in Tokyo, Japan, in early January 2021 (1). This Variants has been associated with increased transmissibility (2), and there are concerns that mutations in the spike protein receptor-binding domain might disrupt both vaccine-induced and natural immunity (3,4). As of February 28, 2021, a total of 10 P.1 cases had been identified in the U.S. including the two cases described in this report, followed by one case each in Alaska, Florida, Maryland, and Oklahoma (5).
• Subjects:
  CoronaVirus Infections COVID-19 Humans Public Health Surveillance SARS-CoV-2 Travel-Related Illness
• Source:
  MMWR Morbidity Mortal Weekly Rep. 70(10):346-347
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  33705367
• Pubmed Central ID:
  PMC7951823
• Document Type:
  Journal Article
• Place as Subject:
  Minnesota ; United States
• Pages in Document:
  2 pdf pages
• Volume:
  70
• Issue:
  10
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:882c65a745f8bd7cf977c88817744c670f66fa065e74067edb4291efd2a5f7c4337d24cd8e54f13861b46185ab6ed57d42138c36cef21069b537e76b27d2d5df
• Download URL:
  https://stacks.cdc.gov/view/cdc/104788/cdc_104788_DS1.pdf
• File Type:
  [PDF - 111.69 KB ]