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Toxicological profile for endrin
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March 2021
[PDF-2.63 MB]
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Description:Endrin [2,7:3,6-dimethanonaphth(2,3-b)oxirene, 3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro- (1aα,2β,2aβ,3α,6α,6aβ,7β,7aα)-, CAS No. 72-20-8] was used as a pesticide until the voluntary cancellation of its registration in 1991. It has not been produced or used in the United States since 1991 (EPA 1984a, 1985a, 1986a, 1993; USDA 1993), which greatly reduces the potential for human exposure. This profile also covers endrin aldehyde and endrin ketone, which were never commercial products, but occurred as impurities of endrin or as degradation products (EPA 1985b; IARC 1974; SRI 1987). Because the United States no longer produces or uses endrin, future levels of endrin, endrin aldehyde, and endrin ketone in environmental media are expected to be low. The most significant route of exposure is most likely ingestion of imported foods contaminated with endrin; however, there may also be some localized risks from exposures near waste disposal sites or from groundwater contaminated with endrin.
Version History
Date Description
March 2021 Final toxicological profile released
May 2019 Draft for public comment toxicological profile released
August 1996 Final toxicological profile released
CS274127-A
tp89.pdf
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