Details:

Alternative Title:
J Acquir Immune Defic Syndr
Publisher's site:
http://dx.doi.org/10.1097/QAI.0000000000002583
Personal Author:
Pathmanathan, Ishani ; Nelson, Robert ; de Louvado, Alzira ; Thompson, Ricardo ; Pals, Sherri ; ... More +
Pathmanathan, Ishani ; Nelson, Robert ; de Louvado, Alzira ; Thompson, Ricardo ; Pals, Sherri ; Casavant, Isabelle ; Cardoso, Maria Judite Antonio ; Ujamaa, Dawud ; Bonzela, Juvêncio ; Mikusova, Silvia ; Chivurre, Victor ; Tamele, Stelio ; Sleeman, Katrina ; Zhang, Guoqing ; Zeh, Clement ; Dobbs, Trudy ; Vubil, Adolfo ; Auld, Andrew ; Briggs-Hagen, Melissa ; Vergara, Alfredo ; Couto, Aleny ; MacKellar, Duncan ; Less -
Description:
Background Early antiretroviral therapy (ART) is necessary for HIV epidemic control and depends on early diagnosis and successful linkage to care. Since 2014, annual household-based HIV testing and counselling (HBHTC) and linkage services have been provided through the Chókwè Health and Demographic Surveillance System (CHDSS) for residents testing HIV-positive in this high HIV-burden district. Methods District-wide Test and Start (T&S, ART for all people living with HIV [PLHIV]) began in August 2016, supported by systematic interventions to improve linkage to care and treatment. Annual rounds (R) of random household surveys were conducted to assess trends in population prevalence of ART use and viral load suppression (VLS; <1000 viral RNA copies/mL). Results Between R1 (April 2014-April 2015) and R5 (April 2018-Mar 2019), 46,090 (67.2%) of 68,620 residents aged 15-59 years were tested for HIV at home at least once, and 3,711 were newly diagnosed with HIV and provided linkage services. Population prevalence of current ART use among PLHIV increased from 65.0% to 87.5% between R1 and R5. ART population prevalence was lowest among men aged 25-34 (67.8%) and women 15-24 (78.0%) years, and highest among women aged 35-44 (93.6%) and 45-59 years (93.7%) in R5. VLS prevalence increased among all PLHIV aged 15-59 years from 52.0% in R1 to 78.3% in R5. Discussion Between 2014 and 2019, CHDSS residents surpassed the UNAIDS targets of ≥81% of PLHIV on ART and ≥73% virally suppressed. This achievement supports the combination of efforts from HBHTC, support for linkage to care and treatment, and continued investments in T&S implementation.
Subject:
[+]
Adolescent
Adult
Anti-HIV Agents
Antiretroviral Therapy Coverage
Article
CD4 Lymphocyte Count
Female
Health Care Surveys
HIV Infections
HIV Testing
Humans
Male
Mass Screening
Middle Aged
Mozambique
Population Surveillance
Population Viral Suppression
Prevalence
UNAIDS 90 90 90
Viral Load
Young Adult

Source:
J Acquir Immune Defic Syndr. 86(4):e97-e105 ;
Pubmed ID:
33252546
Pubmed Central ID:
PMC7970427
Document Type:
Journal Article ;
Funding:
CC999999/ImCDC/Intramural CDC HHSUnited States/ ; PEPFAR/PEPFARUnited States/ ;
CC999999/ImCDC/Intramural CDC HHSUnited States/ ; PEPFAR/PEPFARUnited States/ ; Less -
Place as Subject:
Mozambique ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:405fa7e6c368a877585a8ca5d5daabab5d80bbd0aacf5d5a77b91fd3183d676c
File Type:

Supporting Files

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