Reduced Rotavirus Vaccine Effectiveness Among Children Born During the Rotavirus Season: A Pooled Analysis of 5 Case-Control Studies From the Americas

Details

• Alternative Title:
  Clin Infect Dis
• Personal Author:
  Premkumar, Prasanna S. ; Parashar, Umesh D. ; Gastanaduy, Paul A. ; McCracken, John P. ; de Oliveira, Lucia Helena ; Payne, Daniel C. ; Patel, Manish M. ; Tate, Jacqueline E. ; Lopman, Ben A.
• Description:
  Using data from rotavirus vaccine effectiveness (VE) studies, we assessed whether rotavirus season modifies rotavirus VE in infants. In the first year of life, adjusted VE was 72% for children born during rotavirus season and 84% for children born in other months (P = .01). Seasonal factors may interfere with vaccine performance.
• Subjects:
  Americas Article Birth Seasons Case-Control Studies Female Humans Infant Male Pooled Analysis Rotavirus Disease Rotavirus Infections Rotavirus Vaccines Treatment Outcome

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• Source:
  Clin Infect Dis. 60(7):1075-1078
• Pubmed ID:
  25452592
• Pubmed Central ID:
  PMC7968047
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHS/United States
• Volume:
  60
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:106f6ddd39010965d6810edb6865cd3e169f323ba6262ad1609b9ea959ec8ef3
• Download URL:
  https://stacks.cdc.gov/view/cdc/104315/cdc_104315_DS1.pdf
• File Type:
  [PDF - 230.18 KB ]