Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV

Gil, Eliza; Sweeney, Nicola; Barrett, Veronica; Morris-Jones, Stephen; Miller, Robert F.; Johnston, Victoria J.; Brown, Michael

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Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV

03/01/2021
By Gil, Eliza ; Sweeney, Nicola ; Barrett, Veronica ; ...
Source: Emerg Infect Dis. 27(3):944-948

[PDF-1.33 MB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Gil, Eliza ; Sweeney, Nicola ; Barrett, Veronica ; Morris-Jones, Stephen ; Miller, Robert F. ; ... More +

Gil, Eliza ; Sweeney, Nicola ; Barrett, Veronica ; Morris-Jones, Stephen ; Miller, Robert F. ; Johnston, Victoria J. ; Brown, Michael Less -
Description:

Nontuberculous mycobacteria can cause disseminated infections in immunocompromised patients and are challenging to treat because of antimicrobial resistance and adverse effects of prolonged multidrug treatment. We report successful treatment with bedaquiline, a novel antimycobacterial drug, as part of combination therapy for 2 patients with disseminated nontuberculous mycobacteria co-infected with HIV.
Subjects:

[+]

18Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography Imaging Antibacterial Drugs Antiinfective Drugs Antimicrobial Resistance Antitubercular Drugs Bacteria Bedaquiline Bedaquiline As Treatment For Disseminated Nontuberculous Mycobacteria Infection In 2 Patients Co-Infected With Hiv Co-Infection Dispatch Hiv Mycobacteriaceae Mycobacterium Mycobacterium Abscessus Mycobacterium Avium Nontuberculous Mycobacteria Ntm Respiratory Infections Tuberculosis And Other Mycobacteria Viruses
Source:

Emerg Infect Dis. 27(3):944-948
Pubmed ID:

33622490
Pubmed Central ID:

PMC7920675
Document Type:

Journal Article
Volume:

27
Issue:

3
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:a29e38fe3944e30800cbab35915eb060249cbefb9af08ffb3add6916b9cd378f
Download URL:

https://stacks.cdc.gov/view/cdc/104036/cdc_104036_DS1.pdf
File Type:

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