Symptom Profiles and Progression in Hospitalized and Nonhospitalized Patients with Coronavirus Disease, Colorado, USA, 2020

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Vahey, Grace M. ; Marshall, Kristen E. ; McDonald, Emily ; Martin, Stacey W. ; Tate, Jacqueline E. ; Midgley, Claire M. ; Killerby, Marie E. ; Kawasaki, Breanna ; Herlihy, Rachel K. ; Alden, Nisha B. ; Staples, J. Erin
• Corporate Authors:
  on behalf of the Colorado Investigation Team2
• Description:
  To improve recognition of coronavirus disease (COVID-19) and inform clinical and public health guidance, we randomly selected 600 COVID-19 case-patients in Colorado. A telephone questionnaire captured symptoms experienced, when symptoms occurred, and how long each lasted. Among 128 hospitalized patients, commonly reported symptoms included fever (84%), fatigue (83%), cough (73%), and dyspnea (72%). Among 236 nonhospitalized patients, commonly reported symptoms included fatigue (90%), fever (83%), cough (83%), and myalgia (74%). The most commonly reported initial symptoms were cough (21%-25%) and fever (20%-25%). In multivariable analysis, vomiting, dyspnea, altered mental status, dehydration, and wheezing were significantly associated with hospitalization, whereas rhinorrhea, headache, sore throat, and anosmia or ageusia were significantly associated with nonhospitalization. General symptoms and upper respiratory symptoms occurred earlier in disease, and anosmia, ageusia, lower respiratory symptoms, and gastrointestinal symptoms occurred later. Symptoms should be considered alongside other epidemiologic factors in clinical and public health decisions regarding potential COVID-19 cases.
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Child Child, Preschool Coronavirus Infections Cough Covid-19 Disease Progression Dyspnea Fatigue Female Fever Humans Infant Inpatients Male Middle Aged Myalgia Outpatients Symptom Assessment Young Adult

  More +
• Source:
  Emerg Infect Dis. 27(2):385-395
• Pubmed ID:
  33496225
• Pubmed Central ID:
  PMC7853576
• Document Type:
  Journal Article
• Place as Subject:
  Colorado
• Location:
  North America
• Volume:
  27
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:4b27f5e1e66cf3224b198921ba2cad5039b5c42b47f9cf86564491af9d8b72d7
• Download URL:
  https://stacks.cdc.gov/view/cdc/102469/cdc_102469_DS1.pdf
• File Type:
  [PDF - 1.75 MB ]