Estimated Latent Tuberculosis Infection Prevalence and Tuberculosis Reactivation Rates Among Non-U.S.-Born Residents in the United States, from the 2011–2012 National Health and Nutrition Examination Survey

Details

• Alternative Title:
  J Immigr Minor Health
• Personal Author:
  Woodruff, Rachel Yelk ; Hill, Andrew ; Marks, Suzanne ; Navin, Thomas ; Miramontes, Roque
• Description:
  Increased testing and treatment of latent tuberculosis infection (LTBI) among US-residents who were born (or lived) in countries with high rates of TB can hasten progress toward TB elimination. We calculated LTBI prevalence using QuantiFERON®-TB Gold In-Tube results from the 2011 to 2012 National Health and Nutrition Examination Survey (NHANES). LTBI prevalence was highest for persons born in India (31.7%, 95% confidence interval 21.2, 44.5). Non-Hispanic white persons had the lowest LTBI prevalence (6.3% 1.9, 18.9). TB reactivation rate, defined as the number of TB cases not associated with recent transmission per 100 person-years of life with LTBI, was highest for persons born in Vietnam 0.183 (0.117, 0.303). Reactivation rates were lower among persons who had resided in the United States for ≥ 10 years than among those who had resided for < 10 years. Results among high risk populations can guide LTBI targeted testing and treatment among non-U.S.-born residents.
• Subjects:
  • Humans
  • Latent Tuberculosis
  • Nutrition Surveys
  • Prevalence
  • Tuberculin Test
  • Tuberculosis
  • White People
• Keywords:
  • Latent tuberculosis infection
  • LTBI
  • TB reactivation
  • Non-U.S.-born
• Source:
  J Immigr Minor Health. 23(4):806-812
• Pubmed ID:
  32761297
• Pubmed Central ID:
  PMC7862421
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Place as Subject:
  United States
• Volume:
  23
• Issue:
  4
• Download URL:
  https://stacks.cdc.gov/view/cdc/102181/cdc_102181_DS1.pdf
• File Type:
  [PDF - 321.04 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:fecde666e7f3a21547051464217f864db82057083052bf1e3a3fc0845d4b857e