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Sin1 regulates Treg development but is not required for T cell growth and proliferation

CITE Title : Sin1 regulates Treg development but is not required for T cell growth and proliferation Personal Author(s) : Chang, Xing;Lazorchak, Adam S.;Liu, Dou;Su, Bing; Published Date : 6 2012;6-2012; Source : Eur J Immunol. 42(6):1639-1647 URL : https://stacks.cdc.gov/view/cdc/33568 Chang, Xing et al. (2012). Sin1 regulates Treg development but is not required for T cell growth and proliferation. 42(6). Chang, Xing et al. "Sin1 regulates Treg development but is not required for T cell growth and proliferation" 42, no. 6 (2012) Chang, Xing et al. "Sin1 regulates Treg development but is not required for T cell growth and proliferation" vol. 42, no. 6, 2012 Export RIS Citation Information.

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Chang, Xing ;

Lazorchak, Adam S.

6 2012 | Eur J Immunol. 42(6):1639-1647

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Mammalian Sin1 plays key roles in the regulation of mitogen-activated protein kinase (MAPK) and mammalian target of rapamycin (mTOR) signaling. Sin1 i...
Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signaling to suppress tumorigenesis

CITE Title : Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signaling to suppress tumorigenesis Personal Author(s) : Liu, Pengda;Gan, Wenjian;Inuzuka, Hiroyuki;Lazorchak, Adam S;Gao, Daming;Arojo, Omotooke;Liu, Dou;Wan, Lixin;Zhai, Bo;Yu, Yonghao;Yuan, Min;Kim, Byeong Mo;Shaik, Shavali;Menon, Suchithra;Gygi, Steven P.;Lee, Tae Ho;Asara, John M;Manning, Brendan D.;Blenis, John;Su, Bing;Wei, Wenyi; Published Date : 11 2013;11-2013; Source : Nat Cell Biol. 15(11):1340-1350 URL : https://stacks.cdc.gov/view/cdc/23115 Liu, Pengda et al. (2013). Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signaling to suppress tumorigenesis. 15(11). Liu, Pengda et al. "Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signaling to suppress tumorigenesis" 15, no. 11 (2013) Liu, Pengda et al. "Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signaling to suppress tumorigenesis" vol. 15, no. 11, 2013 Export RIS Citation Information.

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Liu, Pengda ;

Gan, Wenjian

11 2013 | Nat Cell Biol. 15(11):1340-1350

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The mechanistic target of rapamycin (mTOR) functions as a critical regulator of cellular growth and metabolism by forming multi-component, yet functio...