Recent Additions

This page includes the documents that were newly added to the repository within the last 30 days.

All these words:

This exact word or phrase:

Any of these words:

None of these words:

Language:

Visit our Help Page for additional assistance

Select a Range:

Select a Format:

Custom Search Builder:

Custom Search Box

Visit our Help Page for additional assistance

Showing 1261 - 1280 of 1996 results

Investigating the Quantitative Toxicological Relationship Between PFAS Alkyl Fluorine Structure and Exposure Levels Leading to Changes in Blood-based Clinical Markers in Rats.

Prussia, Andrew J. ;

Demchuk, Eugene

August 28, 2025 | Journal of Toxicology and Environmental Health. Part A, 2025, v. 88, no. 23

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are persistent organic pollutants, many of which exhibit lowclearance rates. The long-chain PFAS (≥6 perfluorinated carbons), due to low clearance rates, are often perceived to exert a higher toll on human health than short-chain PFAS. However, a comprehensive toxicological and epidemiological co ...

10/09/2026

Supporting Files

Title : Investigating the Quantitative Toxicological Relationship Between PFAS Alkyl Fluorine Structure and Exposure Levels Leading to Changes in Blood-based Clinical Markers in Rats. Personal Author(s) : Prussia, Andrew J.;Demchuk, Eugene; Published Date : August 28, 2025 Pages in Document : 981-996 (25 pdf pages) Source : Journal of Toxicology and Environmental Health. Part A, 2025, v. 88, no. 23 DOI : https://doi.org/10.1080/15287394.2025.2520427 Journal Title : Journal of Toxicology and Environmental Health. Part A
Prussia, A. J., & Demchuk, E. (2025). Investigating the Quantitative Toxicological Relationship Between PFAS Alkyl Fluorine Structure and Exposure Levels Leading to Changes in Blood-based Clinical Markers in Rats. Journal of Toxicology and Environmental Health. Part A, 88(23). https://doi.org/10.1080/15287394.2025.2520427

Prussia, Andrew J. and Eugene Demchuk. "Investigating the Quantitative Toxicological Relationship Between PFAS Alkyl Fluorine Structure and Exposure Levels Leading to Changes in Blood-based Clinical Markers in Rats." Journal of Toxicology and Environmental Health. Part A 88, no. 23 (2025). https://doi.org/10.1080/15287394.2025.2520427.

Prussia, Andrew J., and Eugene Demchuk "Investigating the Quantitative Toxicological Relationship Between PFAS Alkyl Fluorine Structure and Exposure Levels Leading to Changes in Blood-based Clinical Markers in Rats." Journal of Toxicology and Environmental Health. Part A, vol. 88, no. 23, 2025. Stacks. https://doi.org/10.1080/15287394.2025.2520427.
Export RIS Citation Information. TY - Journal Article AU - Prussia, Andrew J. AU - Demchuk, Eugene AB - Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are persistent organic pollutants, many of which exhibit low AB - clearance rates. The long-chain PFAS (≥6 perfluorinated carbons), due to low clearance rates, are often perceived to exert a higher toll on human health than short-chain PFAS. However, a comprehensive toxicological and epidemiological comparison of long- and short-chain PFAS is overdue, leaving significant data gaps and limitations. For the first time, this study investigated the quantitative relationship between overall PFAS fluorine structure (C-F bond), which includes the alkyl chain length as one component, and PFAS doses that trigger changes in rat blood-based clinical markers. Fifteen markers published by the National Toxicology Program (NTP) after 28-day exposure to 7 PFAS with both long- and short-chain perfluorinated alkyl structures were examined. The aim of this study was to (1) determine PFAS doses that trigger changes in the marker levels for hepatic, renal, cardiovascular, and metabolic systems and (2) use these doses in multiple linear regression models to examine relationship to variables describing PFAS chemical structures. Our findings showed a log-linear dependence of alterations in marker levels on PFAS fluorine structure, as measured in the number of alkyl carbon-fluorine (C-F) bonds. Each C-F bond affected the marker effect levels by 0.45 ± 0.01 mmol/kg-day. The variety of studied clinical markers suggests that PFAS exposures led to deviations in multiple biological pathways in the rat animal model, which may inform future research and regulatory decisions. AB - Author manuscript AN - cdc:261279 C4 - PMC12382308 DO - https://doi.org/10.1080/15287394.2025.2520427 IS - 23 J2 - Journal of Toxicology and Environmental Health. Part A KW - Biomarkers KW - Fluorocarbons KW - Environmental Pollutants KW - Animals KW - Fluorine KW - Rats, Sprague-Dawley KW - Male KW - Environmental Exposure KW - Rats KW - Perfluoroalkyl and polyfluoroalkyl substances (PFAS) KW - Perfluoroalkyl acids (PFAAs) KW - Fluorocarbons KW - Clinical markers KW - Dose-response analysis KW - Multiple linear regression models KW - Animals KW - Fluorocarbons KW - Rats KW - Biomarkers KW - Male KW - Environmental Pollutants KW - Rats, Sprague-Dawley KW - Fluorine KW - Environmental Exposure LA - eng PY - 2025 T2 - Journal of Toxicology and Environmental Health. Part A T2 - Journal of Toxicology and Environmental Health. Part A, 2025, v. 88, no. 23 TI - Investigating the Quantitative Toxicological Relationship Between PFAS Alkyl Fluorine Structure and Exposure Levels Leading to Changes in Blood-based Clinical Markers in Rats. VL - 88 UR - https://stacks.cdc.gov/view/cdc/261279 ER -
Medical Mistrust and Willingness to Use Long-Acting PrEP Among Black and Hispanic/Latino MSM.

Raiford, Jerris L ;

MacGowan, Robin J.

November 2025 | AIDS and Behavior, 2025, v. 29, no. 11

Gay, bisexual, and other men who have sex with men (MSM) are disproportionately affected by HIV infection in the United States, especially Black MSM (BMSM) and Hispanic/Latino MSM (HLMSM). Long-acting preexposure prophylaxis (LA PrEP) is effective in preventing HIV; however, medical mistrust may contribute to barriers in uptake among BMSM and HLMSM ...

10/09/2026

Supporting Files

Title : Medical Mistrust and Willingness to Use Long-Acting PrEP Among Black and Hispanic/Latino MSM. Personal Author(s) : Raiford, Jerris L;MacGowan, Robin J.;Stephenson, Rob;Dana, Ruth;Hightow-Weidman, Lisa;Wall, Kristin M;Jones, Jeb;Sullivan, Patrick S.; Published Date : November 2025 Pages in Document : 3582-3594 (21 pdf pages) Source : AIDS and Behavior, 2025, v. 29, no. 11 DOI : https://doi.org/10.1007/s10461-025-04801-z Journal Title : AIDS and Behavior
Raiford, J. L., MacGowan, R. J., Stephenson, R., Dana, R., Hightow-Weidman, L., Wall, K. M., Jones, J., & Sullivan, P. S. (2025). Medical Mistrust and Willingness to Use Long-Acting PrEP Among Black and Hispanic/Latino MSM. AIDS and Behavior, 29(11). https://doi.org/10.1007/s10461-025-04801-z

Raiford, Jerris L, Robin J. MacGowan, Rob Stephenson, Ruth Dana, Lisa Hightow-Weidman, Kristin M Wall, Jeb Jones, and Patrick S. Sullivan. "Medical Mistrust and Willingness to Use Long-Acting PrEP Among Black and Hispanic/Latino MSM." AIDS and Behavior 29, no. 11 (2025). https://doi.org/10.1007/s10461-025-04801-z.

Raiford, Jerris L, et al. "Medical Mistrust and Willingness to Use Long-Acting PrEP Among Black and Hispanic/Latino MSM." AIDS and Behavior, vol. 29, no. 11, 2025. Stacks. https://doi.org/10.1007/s10461-025-04801-z.
Export RIS Citation Information. TY - Journal Article AU - Raiford, Jerris L AU - MacGowan, Robin J. AU - Stephenson, Rob AU - Dana, Ruth AU - Hightow-Weidman, Lisa AU - Wall, Kristin M AU - Jones, Jeb AU - Sullivan, Patrick S. AB - Gay, bisexual, and other men who have sex with men (MSM) are disproportionately affected by HIV infection in the United States, especially Black MSM (BMSM) and Hispanic/Latino MSM (HLMSM). Long-acting preexposure prophylaxis (LA PrEP) is effective in preventing HIV; however, medical mistrust may contribute to barriers in uptake among BMSM and HLMSM. We assessed the role of medical mistrust in BMSM and HLMSM's unwillingness to use LA PrEP. BMSM and HLMSM aged ≥18 years without a previous HIV diagnosis or current PrEP use were recruited through dating and general interest websites/apps. Using Poisson regression with robust standard errors, we conducted multivariate analyses to assess the association between medical mistrust and willingness to use LA PrEP (i.e., injection or rod implanted in the arm) separately for each racial/ethnic group. Over 90% of the 1,126 BMSM and 924 HLMSM in this study were willing to use some form of PrEP; however, only 74% of BMSM and 81% of HLMSM were willing to use PrEP injections, and significantly fewer BMSM (30%) were willing to receive a PrEP implant compared with 44% of HLMSM. After controlling for sociodemographic, behavioral, and clinical covariates, medical mistrust was associated with lower willingness to use LA PrEP for BMSM, but not for HLMSM. Addressing and reducing medical mistrust among BMSM is important to increase the use of LA PrEP as an effective HIV prevention strategy. Addressing structural barriers and building trust within healthcare systems are crucial steps in reducing disparities in HIV infection among BMSM and HLMSM. AB - Author manuscript AN - cdc:261278 C4 - PMC12599396 DO - https://doi.org/10.1007/s10461-025-04801-z IS - 11 J2 - AIDS and Behavior KW - Professional Misconduct KW - History, 20th Century KW - Health Knowledge, Attitudes, Practice KW - Anti-HIV Agents KW - Trust KW - Hispanic or Latino KW - Young Adult KW - Malpractice KW - Homosexuality, Male KW - Sexual and Gender Minorities KW - Pre-Exposure Prophylaxis KW - Patient Acceptance of Health Care KW - Male KW - Humans KW - Middle Aged KW - Black or African American KW - Adult KW - Ethics, Medical KW - HIV Infections KW - MSM KW - Black KW - Hispanic/Latino KW - PrEP KW - long acting KW - willingness KW - medical mistrust KW - Adult KW - Humans KW - Male KW - Middle Aged KW - Young Adult KW - Anti-HIV Agents KW - Black or African American KW - Health Knowledge, Attitudes, Practice KW - Hispanic or Latino KW - HIV Infections KW - Homosexuality, Male KW - Patient Acceptance of Health Care KW - Pre-Exposure Prophylaxis KW - Sexual and Gender Minorities KW - Trust KW - Ethics, Medical KW - Professional Misconduct KW - History, 20th Century KW - Malpractice LA - eng PY - 2025 T2 - AIDS and Behavior T2 - AIDS and Behavior, 2025, v. 29, no. 11 TI - Medical Mistrust and Willingness to Use Long-Acting PrEP Among Black and Hispanic/Latino MSM. VL - 29 UR - https://stacks.cdc.gov/view/cdc/261278 ER -
Invasive Fungal Disease in Solid Organ and Hematopoietic Cell Transplant Recipients, United States.

Gold, Jeremy A. W. ;

Benedict, Kaitlin

July 24, 2025 | Transplant Infectious Disease: An Official Journal of the Transplantation Society, 2025, v. 27, no. 5

Updated benchmark data on invasive fungal disease (IFD) in solid organ transplantation (SOT) and hematopoietic cell transplantation (HCT) recipients are necessary to increase clinical recognition and inform treatment and prevention strategies. We estimated IFD incidence and potential risk factors in transplant recipients in a large US commercial he ...

10/09/2026

Supporting Files

Title : Invasive Fungal Disease in Solid Organ and Hematopoietic Cell Transplant Recipients, United States. Personal Author(s) : Gold, Jeremy A. W.;Benedict, Kaitlin;Sajewski, Elizabeth;Chiller, Tom;Lyman, Meghan;Toda, Mitsuru;Little, Jessica S.;Ostrosky-Zeichner, Luis; Published Date : July 24, 2025 Pages in Document : e70077 (18 pdf pages) Source : Transplant Infectious Disease: An Official Journal of the Transplantation Society, 2025, v. 27, no. 5 DOI : https://doi.org/10.1111/tid.70077 Journal Title : Transplant Infectious Disease: An Official Journal of the Transplantation Society
Gold, J. A. W., Benedict, K., Sajewski, E., Chiller, T., Lyman, M., Toda, M., Little, J. S., & Ostrosky-Zeichner, L. (2025). Invasive Fungal Disease in Solid Organ and Hematopoietic Cell Transplant Recipients, United States. Transplant Infectious Disease: An Official Journal of the Transplantation Society, 27(5). https://doi.org/10.1111/tid.70077

Gold, Jeremy A. W., Kaitlin Benedict, Elizabeth Sajewski, Tom Chiller, Meghan Lyman, Mitsuru Toda, Jessica S. Little, and Luis Ostrosky-Zeichner. "Invasive Fungal Disease in Solid Organ and Hematopoietic Cell Transplant Recipients, United States." Transplant Infectious Disease: An Official Journal of the Transplantation Society 27, no. 5 (2025). https://doi.org/10.1111/tid.70077.

Gold, Jeremy A. W., et al. "Invasive Fungal Disease in Solid Organ and Hematopoietic Cell Transplant Recipients, United States." Transplant Infectious Disease: An Official Journal of the Transplantation Society, vol. 27, no. 5, 2025. Stacks. https://doi.org/10.1111/tid.70077.
Export RIS Citation Information. TY - Journal Article AU - Gold, Jeremy A. W. AU - Benedict, Kaitlin AU - Sajewski, Elizabeth AU - Chiller, Tom AU - Lyman, Meghan AU - Toda, Mitsuru AU - Little, Jessica S. AU - Ostrosky-Zeichner, Luis AB - Updated benchmark data on invasive fungal disease (IFD) in solid organ transplantation (SOT) and hematopoietic cell transplantation (HCT) recipients are necessary to increase clinical recognition and inform treatment and prevention strategies. We estimated IFD incidence and potential risk factors in transplant recipients in a large US commercial health insurance database. AB - We observed patients who received SOT or HCT during 2018-2022 until IFD development, disenrollment, or database end date (July 31, 2023). We calculated incidence (per 1000 person-years) and time to IFD development, comparing demographic features and underlying conditions for IFD versus non-IFD patients. AB - Overall, 9143 patients received an SOT (5667 kidney, 2025 liver, 759 heart, 650 lung, 39 pancreas, 3 intestine), and 5693 patients received an HCT (3519 autologous, 2114 allogeneic, 60 unspecified type). Among SOT patients, 360 developed an IFD (incidence: 21.0 [per 1000 person-years]). Mold infections had the highest incidence (7.1), followed by unspecified mycoses (3.9) and endemic mycoses (3.3). Among HCT patients, 292 developed an IFD (incidence: 28.5), with higher incidence among allogeneic (58.4) versus autologous (12.8) HCT recipients; among all HCT recipients, unspecified mycoses had the highest incidence (8.3), then pneumocystosis (7.6), and mold infections (6.7). Median time to IFD was 173.5 days for SOT recipients and 197.5 days for HCT recipients. IFD risk varied substantially by transplant type, region, and certain underlying conditions. AB - Our results suggest that IFDs remain an important cause of infection among SOT and HCT recipients, particularly later in the posttransplant period, and highlight the need for prevention strategies. AB - Author manuscript AN - cdc:261277 C4 - PMC12289323 DO - https://doi.org/10.1111/tid.70077 IS - 5 J2 - Transplant Infectious Disease: An Official Journal of the Transplantation Society KW - Adolescent KW - Organ Transplantation KW - Female KW - Aged KW - Infant, Newborn KW - Young Adult KW - Invasive Fungal Infections KW - Child KW - Databases, Factual KW - Risk Factors KW - Infant KW - Male KW - Humans KW - Hematopoietic Stem Cell Transplantation KW - Middle Aged KW - Child, Preschool KW - Adult KW - aspergillosis KW - candidiasis KW - cryptococcosis KW - invasive fungal disease KW - pneumocystosis KW - solid organ transplantation KW - stem cell transplantation KW - Hematopoietic Stem Cell Transplantation KW - Humans KW - Male KW - Female KW - Adult KW - Middle Aged KW - Invasive Fungal Infections KW - Organ Transplantation KW - Databases, Factual KW - Risk Factors KW - Infant, Newborn KW - Infant KW - Child, Preschool KW - Child KW - Adolescent KW - Young Adult KW - Aged LA - eng PY - 2025 T2 - Transplant Infectious Disease: An Official Journal of the Transplantation Society T2 - Transplant Infectious Disease: An Official Journal of the Transplantation Society, 2025, v. 27, no. 5 TI - Invasive Fungal Disease in Solid Organ and Hematopoietic Cell Transplant Recipients, United States. VL - 27 UR - https://stacks.cdc.gov/view/cdc/261277 ER -
Expansion of tetM-Carrying Neisseria gonorrhoeae in the US, 2018-2024

Helekal, David ;

Mortimer, Tatum D.

July 10, 2025 | The New England Journal of Medicine, 2025, v. 393, no. 2

Doxycycline use for bacterial sexually transmitted infections (STIs) increased in recent years due to changes in treatment guidelines, the shortage of benzathine penicillin for treatment of syphilis, and adoption of doxycycline post-exposure prophylaxis (doxy-PEP). While this increased use is expected to select for doxycycline resistance, particula ...

10/09/2026

Supporting Files

Title : Expansion of tetM-Carrying Neisseria gonorrhoeae in the US, 2018-2024 Personal Author(s) : Helekal, David;Mortimer, Tatum D.;Grad, Yonatan H.; Published Date : July 10, 2025 Pages in Document : 198-200 (3 pdf pages) Source : The New England Journal of Medicine, 2025, v. 393, no. 2 DOI : https://doi.org/10.1056/NEJMc2504010 Journal Title : The New England Journal of Medicine
Helekal, D., Mortimer, T. D., & Grad, Y. H. (2025). Expansion of tetM-Carrying Neisseria gonorrhoeae in the US, 2018-2024. The New England Journal of Medicine, 393(2). https://doi.org/10.1056/NEJMc2504010

Helekal, David, Tatum D. Mortimer, and Yonatan H. Grad. "Expansion of tetM-Carrying Neisseria gonorrhoeae in the US, 2018-2024." The New England Journal of Medicine 393, no. 2 (2025). https://doi.org/10.1056/NEJMc2504010.

Helekal, David, et al. "Expansion of tetM-Carrying Neisseria gonorrhoeae in the US, 2018-2024." The New England Journal of Medicine, vol. 393, no. 2, 2025. Stacks. https://doi.org/10.1056/NEJMc2504010.
Export RIS Citation Information. TY - Journal Article AU - Helekal, David AU - Mortimer, Tatum D. AU - Grad, Yonatan H. AB - Doxycycline use for bacterial sexually transmitted infections (STIs) increased in recent years due to changes in treatment guidelines, the shortage of benzathine penicillin for treatment of syphilis, and adoption of doxycycline post-exposure prophylaxis (doxy-PEP). While this increased use is expected to select for doxycycline resistance, particularly in Neisseria gonorrhoeae, the impact has been unclear. Here, we analyzed over 14,000 publicly available N. gonorrhoeae genome sequences from 2018-2024 generated through the US Centers for Disease Control and Prevention N. gonorrhoeae surveillance system, assessed the distribution of tetM, a plasmid-borne gene conferring high-level (MIC ≥ 16μg/mL) tetracycline resistance, and evaluated the spatial, temporal, and evolutionary dynamics of its spread AB - Author manuscript AN - cdc:261276 C4 - PMC12243957 DO - https://doi.org/10.1056/NEJMc2504010 IS - 2 J2 - The New England Journal of Medicine KW - Syphilis KW - Neisseria gonorrhoeae KW - Plasmids KW - Penicillin G Benzathine KW - Post-Exposure Prophylaxis KW - Doxycycline KW - Tetracycline Resistance KW - Doxycycline KW - Neisseria gonorrhoeae KW - Penicillin G Benzathine KW - Post-Exposure Prophylaxis KW - Syphilis KW - Tetracycline Resistance KW - Plasmids LA - eng PY - 2025 T2 - The New England Journal of Medicine T2 - The New England Journal of Medicine, 2025, v. 393, no. 2 TI - Expansion of tetM-Carrying Neisseria gonorrhoeae in the US, 2018-2024 VL - 393 UR - https://stacks.cdc.gov/view/cdc/261276 ER -
Safety of Hormonal Contraception Among Women With Liver Disease: an Updated Systematic Review.

Kapp, Nathalie ;

Tepper, Naomi K.

July 2026 | qq11, 2026, v. 159

We sought to assess whether, among women with liver disease, there is an increased risk of adverse health effects with the use of hormonal contraception (HC).We conducted a systematic review of six databases from database inception through December 13, 2022. We searched for articles that examined changes in liver lesions and acute and chronic liver ...

10/09/2026

Supporting Files

Title : Safety of Hormonal Contraception Among Women With Liver Disease: an Updated Systematic Review. Personal Author(s) : Kapp, Nathalie;Tepper, Naomi K.;Nguyen, Antoinette T.;Garbarino, Sophia;Kortsmit, Katherine;Curtis, Kathryn M.;Whiteman, Maura K.; Published Date : July 2026 Pages in Document : 111012 (17 pdf pages) Source : qq11, 2026, v. 159 DOI : https://doi.org/10.1016/j.contraception.2025.111012 Journal Title : qq11
Kapp, N., Tepper, N. K., Nguyen, A. T., Garbarino, S., Kortsmit, K., Curtis, K. M., & Whiteman, M. K. (2026). Safety of Hormonal Contraception Among Women With Liver Disease: an Updated Systematic Review. qq11, 159. https://doi.org/10.1016/j.contraception.2025.111012

Kapp, Nathalie, Naomi K. Tepper, Antoinette T. Nguyen, Sophia Garbarino, Katherine Kortsmit, Kathryn M. Curtis, and Maura K. Whiteman. "Safety of Hormonal Contraception Among Women With Liver Disease: an Updated Systematic Review." qq11 159 (2026). https://doi.org/10.1016/j.contraception.2025.111012.

Kapp, Nathalie, et al. "Safety of Hormonal Contraception Among Women With Liver Disease: an Updated Systematic Review." qq11, vol. 159, 2026. Stacks. https://doi.org/10.1016/j.contraception.2025.111012.
Export RIS Citation Information. TY - Journal Article AU - Kapp, Nathalie AU - Tepper, Naomi K. AU - Nguyen, Antoinette T. AU - Garbarino, Sophia AU - Kortsmit, Katherine AU - Curtis, Kathryn M. AU - Whiteman, Maura K. AB - We sought to assess whether, among women with liver disease, there is an increased risk of adverse health effects with the use of hormonal contraception (HC). AB - We conducted a systematic review of six databases from database inception through December 13, 2022. We searched for articles that examined changes in liver lesions and acute and chronic liver disease with the use of HC or after discontinuation of HC. We assessed the risk of bias for each study and certainty of evidence for all outcomes. AB - Thirteen articles met inclusion criteria, one with low risk of bias and the others with high risk of bias: three studies (four articles) were of women with focal nodular hyperplasia (FNH), five studies were of hepatocellular adenoma (HCA), and four studies were of acute or chronic hepatitis. The size and/or number of FNH lesions were generally not influenced by HC use. HCA progression was generally higher among current combined oral contraception (COC) users than those who discontinued, and lesions were stable or regressed in most women who discontinued COC or used progestin-only contraception. Studies found that viral hepatitis generally did not progress or increase in severity with the use of COC. AB - Overall, a limited body of evidence suggested changes in FNH lesions were independent of hormonal contraceptive use. Estrogen-containing contraceptive method use was associated with HCA lesion progression; lesions generally remained stable with progestin-only contraceptive use. COC use did not increase progression or severity of disease among those with viral hepatitis. The certainty of evidence for all outcomes was very low. AB - Liver conditions such as liver lesions, viral hepatitis, and cirrhosis are increasingly common in women of reproductive age. Information in this review can be used by health care providers when counseling women with liver disease about the safe use of contraception. AB - Author manuscript AN - cdc:261275 C4 - PMC12369956 DO - https://doi.org/10.1016/j.contraception.2025.111012 J2 - qq11 KW - Hepatitis KW - Systematic Review KW - Hormonal Contraception KW - Focal Nodular Hyperplasia KW - Contraceptives, Oral, Combined KW - Liver Diseases KW - Adenoma, Liver Cell KW - Combined oral contraception KW - Focal nodular hyperplasia KW - Hepatitis KW - Hepatocellular adenoma KW - Hormonal contraception KW - Liver disease KW - Systematic review KW - Contraceptives, Oral, Combined KW - Focal Nodular Hyperplasia KW - Hepatitis KW - Adenoma, Liver Cell KW - Hormonal Contraception KW - Liver Diseases KW - Systematic Review LA - eng PY - 2026 T2 - qq11 T2 - qq11, 2026, v. 159 TI - Safety of Hormonal Contraception Among Women With Liver Disease: an Updated Systematic Review. VL - 159 UR - https://stacks.cdc.gov/view/cdc/261275 ER -
Changes in the PrEP Care Cascade in People Who Inject Drugs in 2018 and 2022.

Spencer, Hunter C. ;

Town, Matthew A.

December 2025 | AIDS and Behavior, 2025, v. 29, no. 12

HIV pre-exposure prophylaxis (PrEP) prevents HIV transmission. However, PrEP remains underutilized among people who inject drugs (PWID), even when clinically indicated. Here, we assess changes in PrEP awareness, access, and use in 2018 and 2022 and factors associated with PrEP awareness in 2022. We analyzed a sample of PWID not living with HIV with ...

10/09/2026

Supporting Files

Title : Changes in the PrEP Care Cascade in People Who Inject Drugs in 2018 and 2022. Personal Author(s) : Spencer, Hunter C.;Town, Matthew A.;Sevillano, LaLaine;Lipira, Lauren;Menza, Tim W.; Published Date : December 2025 Pages in Document : 3822-3829 (16 pdf pages) Source : AIDS and Behavior, 2025, v. 29, no. 12 DOI : https://doi.org/10.1007/s10461-025-04819-3 Journal Title : AIDS and Behavior
Spencer, H. C., Town, M. A., Sevillano, L., Lipira, L., & Menza, T. W. (2025). Changes in the PrEP Care Cascade in People Who Inject Drugs in 2018 and 2022. AIDS and Behavior, 29(12). https://doi.org/10.1007/s10461-025-04819-3

Spencer, Hunter C., Matthew A. Town, LaLaine Sevillano, Lauren Lipira, and Tim W. Menza. "Changes in the PrEP Care Cascade in People Who Inject Drugs in 2018 and 2022." AIDS and Behavior 29, no. 12 (2025). https://doi.org/10.1007/s10461-025-04819-3.

Spencer, Hunter C., et al. "Changes in the PrEP Care Cascade in People Who Inject Drugs in 2018 and 2022." AIDS and Behavior, vol. 29, no. 12, 2025. Stacks. https://doi.org/10.1007/s10461-025-04819-3.
Export RIS Citation Information. TY - Journal Article AU - Spencer, Hunter C. AU - Town, Matthew A. AU - Sevillano, LaLaine AU - Lipira, Lauren AU - Menza, Tim W. AB - HIV pre-exposure prophylaxis (PrEP) prevents HIV transmission. However, PrEP remains underutilized among people who inject drugs (PWID), even when clinically indicated. Here, we assess changes in PrEP awareness, access, and use in 2018 and 2022 and factors associated with PrEP awareness in 2022. We analyzed a sample of PWID not living with HIV with an indication for PrEP based on National HIV Behavioral Surveillance (NHBS) in Portland, Oregon during the 2018 and 2022 survey cycles. We compared PrEP awareness, access, and use in 2018 and 2022 with χ AB - . Using 2018 and 2022 data, we compared PrEP awareness between the two years with a Poisson regression. Using 2022 data, we assessed factors associated with PrEP awareness. Compared to 2018, PrEP awareness was higher in 2022 (33% vs 17%, p < 0.001, aPR = 1.24, 95% CI = 1.14-1.36). There were no significant differences in PrEP access or use between 2018 to 2022. In the 2022 sample, PrEP awareness was higher among those with Hispanic ethnicity compared to white, non-Hispanic PWID (aPR = 2.18, 95% CI = 1.21-3.90) and previous drug treatment (aPR = 1.79, 95% CI = 1.20-2.69). Although PrEP awareness was higher in 2022 than 2018, PrEP access and use were unchanged and remained rare. PrEP use among PWID remains insufficient to meet national Ending the HIV Epidemic goals. AB - Author manuscript AN - cdc:261274 C4 - PMC12676974 DO - https://doi.org/10.1007/s10461-025-04819-3 IS - 12 J2 - AIDS and Behavior KW - Female KW - Health Knowledge, Attitudes, Practice KW - Anti-HIV Agents KW - Young Adult KW - Pre-Exposure Prophylaxis KW - Surveys and Questionnaires KW - Drug Users KW - Male KW - Humans KW - Middle Aged KW - Health Services Accessibility KW - Substance Abuse, Intravenous KW - Adult KW - HIV Infections KW - HIV KW - HIV Prevention KW - Pre-exposure prophylaxis (PrEP) KW - PrEP awareness KW - people who inject drugs (PWID) KW - Humans KW - HIV Infections KW - Substance Abuse, Intravenous KW - Pre-Exposure Prophylaxis KW - Male KW - Female KW - Adult KW - Middle Aged KW - Health Knowledge, Attitudes, Practice KW - Anti-HIV Agents KW - Health Services Accessibility KW - Drug Users KW - Young Adult KW - Surveys and Questionnaires LA - eng PY - 2025 T2 - AIDS and Behavior T2 - AIDS and Behavior, 2025, v. 29, no. 12 TI - Changes in the PrEP Care Cascade in People Who Inject Drugs in 2018 and 2022. VL - 29 UR - https://stacks.cdc.gov/view/cdc/261274 ER -
Assessment of School-Related Covid-19 Concerns Among Parents of School-Aged Children - United States, January 2021.

Young, Emily ;

Strine, Tara

July 9, 2025 | Planning & Changing, 2025, v. 51, no. 34

COVID-19-related disruptions to K-12 schooling were documented throughout the pandemic, along with parental concerns about the impact of COVID-19 on children's education. This study describes school-related COVID-19 concerns among parents of school-aged children across the United States in January 2021. Cross-sectional data (n=916) were analyzed fr ...

10/09/2026

Supporting Files

Title : Assessment of School-Related Covid-19 Concerns Among Parents of School-Aged Children - United States, January 2021. Personal Author(s) : Young, Emily;Strine, Tara;Szucs, Leigh;Swanson, Megan;Lane, Rashon;Bamkole, Omoshalewa;Sliwa, Sarah;Mark-Carew, Miguella;Verlenden, Jorge V.; Published Date : July 9, 2025 Pages in Document : 142-158 (13 pdf pages) Source : Planning & Changing, 2025, v. 51, no. 34 DOI : https://doi.org/10.1377/hlthaff.2020.00598 Journal Title : Planning & Changing
Young, E., Strine, T., Szucs, L., Swanson, M., Lane, R., Bamkole, O., Sliwa, S., Mark-Carew, M., & Verlenden, J. V. (2025). Assessment of School-Related Covid-19 Concerns Among Parents of School-Aged Children - United States, January 2021. Planning & Changing, 51(34). https://doi.org/10.1377/hlthaff.2020.00598

Young, Emily, Tara Strine, Leigh Szucs, Megan Swanson, Rashon Lane, Omoshalewa Bamkole, Sarah Sliwa, Miguella Mark-Carew, and Jorge V. Verlenden. "Assessment of School-Related Covid-19 Concerns Among Parents of School-Aged Children - United States, January 2021." Planning & Changing 51, no. 34 (2025). https://doi.org/10.1377/hlthaff.2020.00598.

Young, Emily, et al. "Assessment of School-Related Covid-19 Concerns Among Parents of School-Aged Children - United States, January 2021." Planning & Changing, vol. 51, no. 34, 2025. Stacks. https://doi.org/10.1377/hlthaff.2020.00598.
Export RIS Citation Information. TY - Journal Article AU - Young, Emily AU - Strine, Tara AU - Szucs, Leigh AU - Swanson, Megan AU - Lane, Rashon AU - Bamkole, Omoshalewa AU - Sliwa, Sarah AU - Mark-Carew, Miguella AU - Verlenden, Jorge V. AB - COVID-19-related disruptions to K-12 schooling were documented throughout the pandemic, along with parental concerns about the impact of COVID-19 on children's education. This study describes school-related COVID-19 concerns among parents of school-aged children across the United States in January 2021. Cross-sectional data (n=916) were analyzed from parents of children enrolled in public or private K-12 schools through an opt-in internet panel survey. Weighted prevalence estimates were calculated based on the U.S. Census Current Population Survey and differences were examined by race/ethnicity. Analyses were performed using SAS, version 9.4, with a significance level of p<0.05. Almost half of parents (46.4%) reported their children received virtual-only learning, 24.0% in-person only learning, and 29.6% combined in-person/virtual learning during fall 2020. School learning mode differed by parental race/ethnicity (p = 0.01). Parents reported concerns (somewhat/very concerned) about educational quality (85.2%) and disruption to routines due to virtual learning (70.8%), as well as children contracting COVID-19 at school (82.9%). Parent concerns about children contracting COVID-19 at school differed across racial and ethnic groups (p = 0.03), with a higher proportion of non-Hispanic Black parents (94.0%; p = 0.003) reporting concerns than non-Hispanic white parents (80.2%). Results document racial and ethnic differences in parental concern about the pandemic's impact on children's school experiences. Intentional monitoring and understanding of parental concerns may help education and public health leaders provide more effective supports for students and families as new school-related emergencies arise. AB - Author manuscript AN - cdc:261273 C4 - PMC12238931 DO - https://doi.org/10.1377/hlthaff.2020.00598 IS - 34 J2 - Planning & Changing KW - Emergencies KW - Cross-Sectional Studies KW - Ethnicity KW - Internet KW - Pandemics KW - Students KW - Prevalence KW - Parents KW - Public Health KW - Censuses KW - COVID-19 KW - Education, Distance KW - Schools KW - parental concerns KW - COVID-19 KW - racial and ethnic differences KW - educational leadership KW - emergency preparedness and communication KW - COVID-19 KW - Censuses KW - Cross-Sectional Studies KW - Education, Distance KW - Emergencies KW - Ethnicity KW - Pandemics KW - Prevalence KW - Public Health KW - Internet KW - Parents KW - Students LA - eng PY - 2025 T2 - Planning & Changing T2 - Planning & Changing, 2025, v. 51, no. 34 TI - Assessment of School-Related Covid-19 Concerns Among Parents of School-Aged Children - United States, January 2021. VL - 51 UR - https://stacks.cdc.gov/view/cdc/261273 ER -
Incentivized Community-Based Syphilis Screening: Uptake, Yield, and Cost.

O'Connell, Meghan Curry ;

Duran, Tinka

December 2025 | Sexually Transmitted Diseases, 2025, v. 52, no. 12

High and increasing syphilis rates among American Indian/Alaska Native communities and particularly among American Indian/Alaska Native women and infants call for immediate interventions to reach and offer syphilis testing to sexually active populations paired with timely treatment.The Great Plains Tribal Epidemiology Center within the Great Plains ...

10/09/2026

Supporting Files

Title : Incentivized Community-Based Syphilis Screening: Uptake, Yield, and Cost. Personal Author(s) : O'Connell, Meghan Curry;Duran, Tinka;Shewbrooks, Sarah;Wang, Cheng;Broghammer, Tyler;Weasel, Emily Good;Taylor, Melanie M.;Means, Tipi; Published Date : December 2025 Pages in Document : 775-779 (12 pdf pages) Source : Sexually Transmitted Diseases, 2025, v. 52, no. 12 DOI : https://doi.org/10.1097/OLQ.0000000000002219 Journal Title : Sexually Transmitted Diseases
O'Connell, M. C., Duran, T., Shewbrooks, S., Wang, C., Broghammer, T., Weasel, E. G., Taylor, M. M., & Means, T. (2025). Incentivized Community-Based Syphilis Screening: Uptake, Yield, and Cost. Sexually Transmitted Diseases, 52(12). https://doi.org/10.1097/OLQ.0000000000002219

O'Connell, Meghan Curry, Tinka Duran, Sarah Shewbrooks, Cheng Wang, Tyler Broghammer, Emily Good Weasel, Melanie M. Taylor, and Tipi Means. "Incentivized Community-Based Syphilis Screening: Uptake, Yield, and Cost." Sexually Transmitted Diseases 52, no. 12 (2025). https://doi.org/10.1097/OLQ.0000000000002219.

O'Connell, Meghan Curry, et al. "Incentivized Community-Based Syphilis Screening: Uptake, Yield, and Cost." Sexually Transmitted Diseases, vol. 52, no. 12, 2025. Stacks. https://doi.org/10.1097/OLQ.0000000000002219.
Export RIS Citation Information. TY - Journal Article AU - O'Connell, Meghan Curry AU - Duran, Tinka AU - Shewbrooks, Sarah AU - Wang, Cheng AU - Broghammer, Tyler AU - Weasel, Emily Good AU - Taylor, Melanie M. AU - Means, Tipi AB - High and increasing syphilis rates among American Indian/Alaska Native communities and particularly among American Indian/Alaska Native women and infants call for immediate interventions to reach and offer syphilis testing to sexually active populations paired with timely treatment. AB - The Great Plains Tribal Epidemiology Center within the Great Plains Tribal Leaders Health Board partnered with a local nontribal health care facility to offer free community-based syphilis testing in Rapid City, South Dakota, starting in December 2022 through June 2024. Participants received cash incentive cards for undergoing testing for syphilis, human immunodeficiency virus (HIV), and hepatitis C virus. AB - Fifteen community testing events were conducted. Laboratory-based syphilis testing was performed on 1434 unique individuals with an average age of 38.8 years. Seventy-six people were diagnosed with syphilis that had previously not been identified (prevalence, 5.3% [76 of 1434]; 51 [67.1%]) were female. Treatment was provided to 80.3% of people with syphilis (61 of 76) within an average of 36 days. In total, the 15 events cost $158,019 ($75,000 administrative staff time + $5100 laboratory staff time + $24,009 laboratory tests + $ 53,910 incentives) or $88 per test performed ($158,019 per 1797). The cost to identify a previously unidentified case was $2079 ($158,019 per 76 newly identified infected persons). AB - This community-based screening event revealed high prevalence of undiagnosed syphilis. Incentives supported community members to access screening services. Collaborations between clinical, tribal, and public health entities to bring diagnosis and treatment services to patients using a community-based approach have clear benefits but need ongoing supportive resources to be maintained. AB - Author manuscript AN - cdc:261272 C4 - PMC12377399 DO - https://doi.org/10.1097/OLQ.0000000000002219 IS - 12 J2 - Sexually Transmitted Diseases KW - Adolescent KW - Female KW - Mass Screening KW - Young Adult KW - Syphilis KW - Prevalence KW - Motivation KW - Male KW - Humans KW - Middle Aged KW - Indians, North American KW - Community Health Services KW - Adult KW - HIV Infections KW - syphilis KW - community-based screening KW - American Indian/Alaska Native KW - Adolescent KW - Adult KW - Female KW - Humans KW - Male KW - Middle Aged KW - Young Adult KW - Community Health Services KW - HIV Infections KW - Indians, North American KW - Mass Screening KW - Motivation KW - Prevalence KW - Syphilis LA - eng PY - 2025 T2 - Sexually Transmitted Diseases T2 - Sexually Transmitted Diseases, 2025, v. 52, no. 12 TI - Incentivized Community-Based Syphilis Screening: Uptake, Yield, and Cost. VL - 52 UR - https://stacks.cdc.gov/view/cdc/261272 ER -
Healthcare Expenditure on Older Adult Non-fatal Falls by State.

Miller, Gabrielle F ;

Haddad, Yara K

July 2025 | Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, July 2025

Falls are a leading preventable cause of death and injury among older adults (65+). Healthcare spending in the USA on non-fatal falls was estimated at $80 billion in 2020. We aim to estimate healthcare spending on older adult non-fatal falls by state.Healthcare spending for all adults was derived from the 2020 Centers for Medicare and Medicaid Serv ...

10/09/2026

Supporting Files

Title : Healthcare Expenditure on Older Adult Non-fatal Falls by State. Personal Author(s) : Miller, Gabrielle F;Haddad, Yara K;Ortmann, Neil;Florence, Curtis; Published Date : July 2025 Pages in Document : ip-2025 (13 pdf pages) Source : Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, July 2025 DOI : https://doi.org/10.1136/ip-2025-045725 Journal Title : Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention
Miller, G. F., Haddad, Y. K., Ortmann, N., & Florence, C. (2025). Healthcare Expenditure on Older Adult Non-fatal Falls by State. Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention. https://doi.org/10.1136/ip-2025-045725

Miller, Gabrielle F, Yara K Haddad, Neil Ortmann, and Curtis Florence. "Healthcare Expenditure on Older Adult Non-fatal Falls by State." Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention (2025). https://doi.org/10.1136/ip-2025-045725.

Miller, Gabrielle F, et al. "Healthcare Expenditure on Older Adult Non-fatal Falls by State." Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, 2025. Stacks. https://doi.org/10.1136/ip-2025-045725.
Export RIS Citation Information. TY - Journal Article AU - Miller, Gabrielle F AU - Haddad, Yara K AU - Ortmann, Neil AU - Florence, Curtis AB - Falls are a leading preventable cause of death and injury among older adults (65+). Healthcare spending in the USA on non-fatal falls was estimated at $80 billion in 2020. We aim to estimate healthcare spending on older adult non-fatal falls by state. AB - Healthcare spending for all adults was derived from the 2020 Centers for Medicare and Medicaid Services (CMS) Health Expenditures by State of Residence files. These data covered three payor types: Medicare, Medicaid and private health insurance (PHI). Using the national 2020 CMS Health Expenditure by Age Group files, the national proportion of healthcare spending for older adults was calculated for each payor type. These national proportions were applied to each state's healthcare spending data to estimate healthcare spending for older adults in each state, adjusted for the proportion of older adults in each state. To estimate the proportion of older adult healthcare spending attributed to non-fatal falls, these adjusted values were combined with the falls-attributable expenditure factors calculated in Haddad (2024). The final state-level estimates of healthcare spending on non-fatal older adult falls were calculated for each payer type: Medicare, Medicaid and PHI. All estimates were inflated to 2023 dollars. AB - Overall state-level spending on non-fatal falls ranged between $112.7 million in Alaska to $8.3 billion in Florida. Per-capita spending estimates ranged between $1085 in Utah to $2262 in Wisconsin. AB - Measuring the cost of non-fatal falls at the state level can help inform regional differences and improve targeted fall prevention efforts. AB - Author manuscript AN - cdc:261271 C4 - PMC13044968 DO - https://doi.org/10.1136/ip-2025-045725 J2 - Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention LA - eng PY - 2025 T2 - Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention T2 - Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention, July 2025 TI - Healthcare Expenditure on Older Adult Non-fatal Falls by State. UR - https://stacks.cdc.gov/view/cdc/261271 ER -
Maternal Occupational Exposure to Noise: Prevalence, Maternal Effects and Infant Outcomes in the National Birth Defects Prevention Study, 1997-2011.

Van Buren, Kristen W ;

Rocheleau, Carissa M

July 2025 | Occupational and Environmental Medicine, 2025, v. 82, no. 5

We investigated associations between occupational noise and gestational diabetes mellitus, pregnancy-related hypertension (including pre-eclampsia/eclampsia), preterm birth and small for gestational age (SGA) infants.Data were analysed for 7889 singleton, live-born infants without major birth defects or chromosomal disorders and their mothers from ...

10/09/2026

Supporting Files

Title : Maternal Occupational Exposure to Noise: Prevalence, Maternal Effects and Infant Outcomes in the National Birth Defects Prevention Study, 1997-2011. Personal Author(s) : Van Buren, Kristen W;Rocheleau, Carissa M;Chen, I-Chen;Sanderson, Wayne T;MacDonald, Leslie A;Masterson, Elizabeth A;Nestoridi, Eirini;Ailes, Elizabeth C; Corporate Authors(s) : the National Birth Defects Prevention Study Published Date : July 2025 Pages in Document : 222-229 (17 pdf pages) Source : Occupational and Environmental Medicine, 2025, v. 82, no. 5 DOI : https://doi.org/10.1136/oemed-2024-109928 Journal Title : Occupational and Environmental Medicine
Van Buren, K. W., Rocheleau, C. M., Chen, I. C., Sanderson, W. T., MacDonald, L. A., Masterson, E. A., Nestoridi, E., & Ailes, E. C. (2025). Maternal Occupational Exposure to Noise: Prevalence, Maternal Effects and Infant Outcomes in the National Birth Defects Prevention Study, 1997-2011. Occupational and Environmental Medicine, 82(5). https://doi.org/10.1136/oemed-2024-109928

Van Buren, Kristen W, Carissa M Rocheleau, I-Chen Chen, Wayne T Sanderson, Leslie A MacDonald, Elizabeth A Masterson, Eirini Nestoridi, and Elizabeth C Ailes. "Maternal Occupational Exposure to Noise: Prevalence, Maternal Effects and Infant Outcomes in the National Birth Defects Prevention Study, 1997-2011." Occupational and Environmental Medicine 82, no. 5 (2025). https://doi.org/10.1136/oemed-2024-109928.

Van Buren, Kristen W, et al. "Maternal Occupational Exposure to Noise: Prevalence, Maternal Effects and Infant Outcomes in the National Birth Defects Prevention Study, 1997-2011." Occupational and Environmental Medicine, vol. 82, no. 5, 2025. Stacks. https://doi.org/10.1136/oemed-2024-109928.
Export RIS Citation Information. TY - Journal Article AU - Van Buren, Kristen W AU - Rocheleau, Carissa M AU - Chen, I-Chen AU - Sanderson, Wayne T AU - MacDonald, Leslie A AU - Masterson, Elizabeth A AU - Nestoridi, Eirini AU - Ailes, Elizabeth C A2 - the National Birth Defects Prevention Study AB - We investigated associations between occupational noise and gestational diabetes mellitus, pregnancy-related hypertension (including pre-eclampsia/eclampsia), preterm birth and small for gestational age (SGA) infants. AB - Data were analysed for 7889 singleton, live-born infants without major birth defects or chromosomal disorders and their mothers from the National Birth Defects Prevention Study from 1997 to 2011. Typical maternal occupational noise exposure in all jobs held from 1 month prior to conception through the end of pregnancy was estimated by expert rater and categorised as quiet (<60 A-weighted decibels (dBA)), low (60-75 dBA), moderate (76-84 dBA) or loud (>85 dBA). Multiple logistic regression was used to estimate associations (adjusted ORs and 95% CIs) between noise exposure levels and outcomes. AB - Approximately 77.4% of pregnant workers had quiet levels of occupational noise exposure, 11.0%, 10.1% and 1.5% had low, moderate and loud exposure levels, respectively. Compared with quiet levels of noise, pregnant workers exposed to low levels of noise had decreased odds of delivering an SGA infant (adjusted OR (aOR)=0.72; 95% CI 0.53 to 0.99) and those exposed to moderate levels had increased odds of delivering an SGA infant (aOR=1.37; 95% CI 1.05 to 1.77). No other significant associations were observed. AB - Maternal occupational noise exposure below the 85 dBA threshold recognised as hazardous may be associated with SGA among infants. Elevated point estimates (>1) were observed for the highest noise exposure category and all outcomes, though CIs were wide and statistical significance was not attained. Further research is warranted to address existing knowledge gaps. AB - Author manuscript AN - cdc:261270 C4 - PMC12362229 DO - https://doi.org/10.1136/oemed-2024-109928 IS - 5 J2 - Occupational and Environmental Medicine KW - Occupational Exposure KW - Pregnancy KW - Premature Birth KW - Female KW - Diabetes, Gestational KW - Infant, Newborn KW - Young Adult KW - Logistic Models KW - Congenital Abnormalities KW - Infant, Small for Gestational Age KW - Pre-Eclampsia KW - Maternal Exposure KW - Prevalence KW - Humans KW - Pregnancy Outcome KW - Adult KW - Noise, Occupational KW - Hypertension, Pregnancy-Induced KW - Humans KW - Female KW - Pregnancy KW - Noise, Occupational KW - Adult KW - Maternal Exposure KW - Infant, Newborn KW - Infant, Small for Gestational Age KW - Occupational Exposure KW - Premature Birth KW - Prevalence KW - Diabetes, Gestational KW - Young Adult KW - Hypertension, Pregnancy-Induced KW - Pregnancy Outcome KW - Logistic Models KW - Congenital Abnormalities KW - Pre-Eclampsia LA - eng PY - 2025 T2 - Occupational and Environmental Medicine T2 - Occupational and Environmental Medicine, 2025, v. 82, no. 5 TI - Maternal Occupational Exposure to Noise: Prevalence, Maternal Effects and Infant Outcomes in the National Birth Defects Prevention Study, 1997-2011. VL - 82 UR - https://stacks.cdc.gov/view/cdc/261270 ER -
Implementation Evaluation of Three Community-Clinical Infection-Related Cancer Prevention and Control Programs in New York City: Lessons Learned From Leveraging Community Health Worker Strategies to Enhance Reach and Fit For Asian American Communiti

Lee, Matthew ;

Kranick, Julie

July 2026 | Community Health Equity Research & Policy, 2026, v. 46, no. 4

BackgroundCommunity health workers (CHW) can perform unique functions to facilitate the implementation of evidence-based interventions for infection-related cancer prevention and control, and alleviate minoritized and immigration-related disparities.PurposeWe describe the implementation evaluation of three CHW-delivered infection-related cancer pro ...

10/09/2026

Supporting Files

Title : Implementation Evaluation of Three Community-Clinical Infection-Related Cancer Prevention and Control Programs in New York City: Lessons Learned From Leveraging Community Health Worker Strategies to Enhance Reach and Fit For Asian American Communiti Personal Author(s) : Lee, Matthew;Kranick, Julie;Foster, Victoria;Chebli, Perla;Yusuf, Yousra;Trinh-Shevrin, Chau;Kwon, Simona C.; Published Date : July 2026 Pages in Document : 445-453 (12 pdf pages) Source : Community Health Equity Research & Policy, 2026, v. 46, no. 4 DOI : https://doi.org/10.1177/2752535X251357464 Journal Title : Community Health Equity Research & Policy
Lee, M., Kranick, J., Foster, V., Chebli, P., Yusuf, Y., Trinh-Shevrin, C., & Kwon, S. C. (2026). Implementation Evaluation of Three Community-Clinical Infection-Related Cancer Prevention and Control Programs in New York City: Lessons Learned From Leveraging Community Health Worker Strategies to Enhance Reach and Fit For Asian American Communiti. Community Health Equity Research & Policy, 46(4). https://doi.org/10.1177/2752535X251357464

Lee, Matthew, Julie Kranick, Victoria Foster, Perla Chebli, Yousra Yusuf, Chau Trinh-Shevrin, and Simona C. Kwon. "Implementation Evaluation of Three Community-Clinical Infection-Related Cancer Prevention and Control Programs in New York City: Lessons Learned From Leveraging Community Health Worker Strategies to Enhance Reach and Fit For Asian American Communiti." Community Health Equity Research & Policy 46, no. 4 (2026). https://doi.org/10.1177/2752535X251357464.

Lee, Matthew, et al. "Implementation Evaluation of Three Community-Clinical Infection-Related Cancer Prevention and Control Programs in New York City: Lessons Learned From Leveraging Community Health Worker Strategies to Enhance Reach and Fit For Asian American Communiti." Community Health Equity Research & Policy, vol. 46, no. 4, 2026. Stacks. https://doi.org/10.1177/2752535X251357464.
Export RIS Citation Information. TY - Journal Article AU - Lee, Matthew AU - Kranick, Julie AU - Foster, Victoria AU - Chebli, Perla AU - Yusuf, Yousra AU - Trinh-Shevrin, Chau AU - Kwon, Simona C. AB - BackgroundCommunity health workers (CHW) can perform unique functions to facilitate the implementation of evidence-based interventions for infection-related cancer prevention and control, and alleviate minoritized and immigration-related disparities.PurposeWe describe the implementation evaluation of three CHW-delivered infection-related cancer programs focused on Asian American (AA) communities in New York City: 1) a H. pylori treatment adherence program for Chinese and Korean Americans; 2) a HPV screening program for Muslim Americans; and 3) a hepatitis B screening, linkage to care, and treatment program for AA and other priority communities.MethodsWe conducted semi-structured key informant interviews with multi-level stakeholders from the programs.ResultsLessons learned include the importance of: 1) sustaining engagement and buy-in from implementation partners; 2) prioritizing recipient- and deliverer-centeredness; 3) fostering program flexibility to accommodate multiple implementation settings and to meet dynamic community resources and priorities; and 4) understanding interoperability between the CHW-delivered intervention and the inner setting for effective program implementation.ConclusionsThese findings can inform other efforts to implement CHW-delivered community-clinical cancer programs for AA and other underserved communities to advance health equity. AB - Author manuscript AN - cdc:261269 C4 - PMC12383678 DO - https://doi.org/10.1177/2752535X251357464 IS - 4 J2 - Community Health Equity Research & Policy KW - Female KW - Papillomavirus Infections KW - Community Health Workers KW - Neoplasms KW - Hepatitis B KW - Male KW - Program Evaluation KW - Humans KW - Asian KW - Humans KW - Community Health Workers KW - Asian KW - Neoplasms KW - Program Evaluation KW - Female KW - Male KW - Papillomavirus Infections KW - Hepatitis B LA - eng PY - 2026 T2 - Community Health Equity Research & Policy T2 - Community Health Equity Research & Policy, 2026, v. 46, no. 4 TI - Implementation Evaluation of Three Community-Clinical Infection-Related Cancer Prevention and Control Programs in New York City: Lessons Learned From Leveraging Community Health Worker Strategies to Enhance Reach and Fit For Asian American Communiti VL - 46 UR - https://stacks.cdc.gov/view/cdc/261269 ER -
Transformative Potential of Artificial Intelligence in US CDC HIV Interventions: Balancing Innovation With Health Privacy.

Kamitani, Emiko ;

Koenig, Linda J.

August 2025 | AIDS (London, England), 2025, v. 39, no. 10

Artificial intelligence (AI) holds significant potential to transform HIV prevention and treatment through the application of advanced technologies such as machine learning (ML), deep learning (DL), and generative AI (Gen AI). These technologies can enhance the monitoring, management, and analysis of vast and complex HIV-related datasets, enabling ...

10/09/2026

Supporting Files

Title : Transformative Potential of Artificial Intelligence in US CDC HIV Interventions: Balancing Innovation With Health Privacy. Personal Author(s) : Kamitani, Emiko;Koenig, Linda J.;Sullivan, Patrick; Published Date : August 2025 Pages in Document : 1311-1321 (18 pdf pages) Source : AIDS (London, England), 2025, v. 39, no. 10 DOI : https://doi.org/10.1097/QAD.0000000000004220 Journal Title : AIDS (London, England)
Kamitani, E., Koenig, L. J., & Sullivan, P. (2025). Transformative Potential of Artificial Intelligence in US CDC HIV Interventions: Balancing Innovation With Health Privacy. AIDS (London, England), 39(10). https://doi.org/10.1097/QAD.0000000000004220

Kamitani, Emiko, Linda J. Koenig, and Patrick Sullivan. "Transformative Potential of Artificial Intelligence in US CDC HIV Interventions: Balancing Innovation With Health Privacy." AIDS (London, England) 39, no. 10 (2025). https://doi.org/10.1097/QAD.0000000000004220.

Kamitani, Emiko, et al. "Transformative Potential of Artificial Intelligence in US CDC HIV Interventions: Balancing Innovation With Health Privacy." AIDS (London, England), vol. 39, no. 10, 2025. Stacks. https://doi.org/10.1097/QAD.0000000000004220.
Export RIS Citation Information. TY - Journal Article AU - Kamitani, Emiko AU - Koenig, Linda J. AU - Sullivan, Patrick AB - Artificial intelligence (AI) holds significant potential to transform HIV prevention and treatment through the application of advanced technologies such as machine learning (ML), deep learning (DL), and generative AI (Gen AI). These technologies can enhance the monitoring, management, and analysis of vast and complex HIV-related datasets, enabling more timely predictions of potential risks and improving HIV care strategies. AI is poised to streamline HIV prevention interventions by increasing workforce efficiency, supporting expanded accessibility and sustainability of preexposure prophylaxis (PrEP) care in nontraditional settings, and supporting clinical decision-making. Additionally, when utilized within HIV care systems, AI can help close gaps in diagnosis, treatment, and continuous care engagement. However, to optimize AI's potential in HIV prevention, careful implementation is crucial. Challenges such as reducing bias, ensuring ethical standards (including health privacy standards) are maintained, and mitigating risks like AI hallucinations must be addressed. Thoughtful integration, community consultation, and continuous evaluation will be critical to ensuring that AI plays a beneficial role in HIV prevention and drives innovations that lead to more equitable health outcomes. This editorial review explores AI's transformative potential, focusing on the US CDC's key public health strategies for HIV prevention. When aligning with public health strategies - particularly in countries supported by initiatives like President's Emergency Plan for AIDS Relief (PEPFAR) - AI can contribute significantly to global efforts to end the HIV epidemic. It offers a vision for AI's future application in HIV prevention, emphasizing the need for a holistic and syndemic approach to improving HIV prevention worldwide. AB - Author manuscript AN - cdc:261268 C4 - PMC12409397 DO - https://doi.org/10.1097/QAD.0000000000004220 IS - 10 J2 - AIDS (London, England) KW - Artificial Intelligence KW - Humans KW - Centers for Disease Control and Prevention, U.S. KW - HIV Infections KW - Pre-Exposure Prophylaxis KW - HIV KW - artificial intelligence KW - machine learning KW - deep learning KW - public health KW - Humans KW - Artificial Intelligence KW - Centers for Disease Control and Prevention, U.S. KW - HIV Infections KW - Pre-Exposure Prophylaxis LA - eng PY - 2025 T2 - AIDS (London, England) T2 - AIDS (London, England), 2025, v. 39, no. 10 TI - Transformative Potential of Artificial Intelligence in US CDC HIV Interventions: Balancing Innovation With Health Privacy. VL - 39 UR - https://stacks.cdc.gov/view/cdc/261268 ER -
Bordetella Pertussis Infection and Antibody Dynamics in Household Cohorts in Two South African Communities, 2016 - 2018: Findings From the PHIRST Study.

Moosa, Fahima ;

Kleynhans, Jackie

August 2025 | The Journal of Infection, 2025, v. 91, no. 2

In a cohort study, enrolling new households annually during 2016-2018, we estimated the B. pertussis attack rate using serology and PCR, identified factors associated with seroconversion, and described antibody changes over time. Nasopharyngeal swabs were collected biweekly for 6-10 months annually, with cases defined as individuals testing PCR-pos ...

10/09/2026

Supporting Files

Title : Bordetella Pertussis Infection and Antibody Dynamics in Household Cohorts in Two South African Communities, 2016 - 2018: Findings From the PHIRST Study. Personal Author(s) : Moosa, Fahima;Kleynhans, Jackie;Makhathini, Lillian;du Plessis, Mignon;Tempia, Stefano;McMorrow, Meredith L.;Moyes, Jocelyn;Buys, Amelia;Maake, Lorens;Smit, Sheilagh;Martinson, Neil A.;Kahn, Kathleen;Lebina, Limakatso;Cohen, Cheryl;von Gottberg, Anne;Wolter, Nicole; Published Date : August 2025 Pages in Document : 106550 (25 pdf pages) Source : The Journal of Infection, 2025, v. 91, no. 2 DOI : https://doi.org/10.1016/j.jinf.2025.106550 Journal Title : The Journal of Infection
Moosa, F., Kleynhans, J., Makhathini, L., du Plessis, M., Tempia, S., McMorrow, M. L., Moyes, J., Buys, A., Maake, L., Smit, S., Martinson, N. A., Kahn, K., Lebina, L., Cohen, C., von Gottberg, A., & Wolter, N. (2025). Bordetella Pertussis Infection and Antibody Dynamics in Household Cohorts in Two South African Communities, 2016 - 2018: Findings From the PHIRST Study. The Journal of Infection, 91(2). https://doi.org/10.1016/j.jinf.2025.106550

Moosa, Fahima, Jackie Kleynhans, Lillian Makhathini, Mignon du Plessis, Stefano Tempia, Meredith L. McMorrow, and Jocelyn Moyes, et al.. "Bordetella Pertussis Infection and Antibody Dynamics in Household Cohorts in Two South African Communities, 2016 - 2018: Findings From the PHIRST Study." The Journal of Infection 91, no. 2 (2025). https://doi.org/10.1016/j.jinf.2025.106550.

Moosa, Fahima, et al. "Bordetella Pertussis Infection and Antibody Dynamics in Household Cohorts in Two South African Communities, 2016 - 2018: Findings From the PHIRST Study." The Journal of Infection, vol. 91, no. 2, 2025. Stacks. https://doi.org/10.1016/j.jinf.2025.106550.
Export RIS Citation Information. TY - Journal Article AU - Moosa, Fahima AU - Kleynhans, Jackie AU - Makhathini, Lillian AU - du Plessis, Mignon AU - Tempia, Stefano AU - McMorrow, Meredith L. AU - Moyes, Jocelyn AU - Buys, Amelia AU - Maake, Lorens AU - Smit, Sheilagh AU - Martinson, Neil A. AU - Kahn, Kathleen AU - Lebina, Limakatso AU - Cohen, Cheryl AU - von Gottberg, Anne AU - Wolter, Nicole AB - In a cohort study, enrolling new households annually during 2016-2018, we estimated the B. pertussis attack rate using serology and PCR, identified factors associated with seroconversion, and described antibody changes over time. Nasopharyngeal swabs were collected biweekly for 6-10 months annually, with cases defined as individuals testing PCR-positive at least once. Seroconversion was defined as a ≥4-fold increase in anti-pertussis toxin IgG concentration between consecutive blood draws. Logistic regression was used to identify factors associated with seroconversion among PCR-positive individuals. AB - Among 1509 participants, the serology attack rate was 5.8% (87/1509), 6.2% (94/1509) by PCR, and 9.6% (145/1509) combining both methods. Among PCR-positive cases, 38.3% (36/94) seroconverted, with a mean time to seroconversion of 2.9 months (range: 3 weeks-5.9 months). Younger participants (5-18 years) (adjusted odds ratio (aOR) 6.8, 95% confidence interval (CI) 1.3-35.1) and those with episode durations of ≥7 days (aOR 13.3, 95% CI 3.4-51.1) were more likely to seroconvert. Among the seroconverted, 75.0% (27/36) maintained antibody concentrations >40 IU/ml for at least 12 months post-infection. AB - Almost 10% of participants had B. pertussis infection during follow-up. Less than half of individuals with PCR-confirmed infection seroconverted but maintained elevated antibodies for at least one-year post-infection. AB - Author manuscript AN - cdc:261267 C4 - PMC12477660 DO - https://doi.org/10.1016/j.jinf.2025.106550 IS - 2 J2 - The Journal of Infection KW - Adolescent KW - Female KW - Antibodies, Bacterial KW - Polymerase Chain Reaction KW - Nasopharynx KW - Family Characteristics KW - Whooping Cough KW - Young Adult KW - Immunoglobulin G KW - Child KW - Cohort Studies KW - Pertussis Toxin KW - Infant KW - Seroconversion KW - Male KW - Bordetella pertussis KW - Middle Aged KW - Humans KW - Child, Preschool KW - Adult KW - B. pertussis KW - Real-time PCR KW - ELISA KW - Seroconversion KW - Anti-PT IgG KW - Antibodies KW - Antibody dynamics KW - Humans KW - Whooping Cough KW - Male KW - Female KW - Bordetella pertussis KW - Antibodies, Bacterial KW - Child, Preschool KW - Adult KW - Adolescent KW - Cohort Studies KW - Child KW - Immunoglobulin G KW - Young Adult KW - Infant KW - Seroconversion KW - Family Characteristics KW - Middle Aged KW - Nasopharynx KW - Pertussis Toxin KW - Polymerase Chain Reaction LA - eng PY - 2025 T2 - The Journal of Infection T2 - The Journal of Infection, 2025, v. 91, no. 2 TI - Bordetella Pertussis Infection and Antibody Dynamics in Household Cohorts in Two South African Communities, 2016 - 2018: Findings From the PHIRST Study. VL - 91 UR - https://stacks.cdc.gov/view/cdc/261267 ER -
Dead Deer do Tell Tales: Infestation of Road-killed White-tailed Deer by Juvenile Ixodes Scapularis (Ixodida: Ixodidae) Ticks.

Landesman, William J. ;

Serra, Abigail C.

July 2025 | Journal of Medical Entomology, 2025, v. 62, no. 5

The white-tailed deer (Odocoileus virginianus) contributes indirectly to the enzootic circulation of the Lyme disease pathogen, Borrelia burgdorferi by serving as the primary reproductive host for adult-stage blacklegged ticks (Ixodes scapularis). The role of white-tailed deer as a host for juvenile life stages is less well understood, in part beca ...

10/09/2026

Supporting Files

Title : Dead Deer do Tell Tales: Infestation of Road-killed White-tailed Deer by Juvenile Ixodes Scapularis (Ixodida: Ixodidae) Ticks. Personal Author(s) : Landesman, William J.;Serra, Abigail C.;Allan, Brian F.; Published Date : July 2025 Pages in Document : 1372-1376 (10 pdf pages) Source : Journal of Medical Entomology, 2025, v. 62, no. 5 DOI : https://doi.org/10.1093/jme/tjaf094 Journal Title : Journal of Medical Entomology
Landesman, W. J., Serra, A. C., & Allan, B. F. (2025). Dead Deer do Tell Tales: Infestation of Road-killed White-tailed Deer by Juvenile Ixodes Scapularis (Ixodida: Ixodidae) Ticks. Journal of Medical Entomology, 62(5). https://doi.org/10.1093/jme/tjaf094

Landesman, William J., Abigail C. Serra, and Brian F. Allan. "Dead Deer do Tell Tales: Infestation of Road-killed White-tailed Deer by Juvenile Ixodes Scapularis (Ixodida: Ixodidae) Ticks." Journal of Medical Entomology 62, no. 5 (2025). https://doi.org/10.1093/jme/tjaf094.

Landesman, William J., et al. "Dead Deer do Tell Tales: Infestation of Road-killed White-tailed Deer by Juvenile Ixodes Scapularis (Ixodida: Ixodidae) Ticks." Journal of Medical Entomology, vol. 62, no. 5, 2025. Stacks. https://doi.org/10.1093/jme/tjaf094.
Export RIS Citation Information. TY - Journal Article AU - Landesman, William J. AU - Serra, Abigail C. AU - Allan, Brian F. AB - The white-tailed deer (Odocoileus virginianus) contributes indirectly to the enzootic circulation of the Lyme disease pathogen, Borrelia burgdorferi by serving as the primary reproductive host for adult-stage blacklegged ticks (Ixodes scapularis). The role of white-tailed deer as a host for juvenile life stages is less well understood, in part because their periods of activity typically fall outside of most white-tailed deer hunting seasons. We inspected 22 road-killed deer for all stages of blacklegged ticks in Rutland County, Vermont from May to August in 2020, 2021, and 2024. Adult-stage blacklegged ticks were found attached to ten deer in May and early June. Larval-stage ticks, including ones that were partially engorged, were found on 3/5 deer inspected by hanging the head, hide, and legs over water for approximately 24 hours. We directly observed 7 nymphal-stage ticks attached to one additional deer. This study adds to a growing body of evidence that the role of juvenile feeding on white-tailed deer may be underestimated and demonstrates that the study of road-killed deer may improve our understanding of how populations of blacklegged ticks are maintained among wildlife communities. AB - Author manuscript AN - cdc:261266 C4 - PMC12351483 DO - https://doi.org/10.1093/jme/tjaf094 IS - 5 J2 - Journal of Medical Entomology KW - Ixodes KW - Deer KW - Larva KW - Female KW - Nymph KW - Animals KW - Vermont KW - Tick Infestations KW - Ixodes scapularis KW - Odocoileus virginianus KW - feeding behavior KW - Animals KW - Deer KW - Ixodes KW - Tick Infestations KW - Nymph KW - Vermont KW - Larva KW - Female LA - eng PY - 2025 T2 - Journal of Medical Entomology T2 - Journal of Medical Entomology, 2025, v. 62, no. 5 TI - Dead Deer do Tell Tales: Infestation of Road-killed White-tailed Deer by Juvenile Ixodes Scapularis (Ixodida: Ixodidae) Ticks. VL - 62 UR - https://stacks.cdc.gov/view/cdc/261266 ER -
Genomic Loci and Molecular Genetic Mechanisms For Hidradenitis Suppurativa.

Broadaway, K. Alaine ;

Sun, Quan

July 2025 | The British Journal of Dermatology, 2025, v. 193, no. 5

Hidradenitis suppurativa (HS) is a common, chronic and debilitating inflammatory disease that most commonly affects intertriginous skin. Despite its high heritability, the genetic underpinnings of HS remain poorly understood.To identify genetic signals associated with HS, determine genetic relationships with other diseases and investigate potential ...

10/09/2026

Supporting Files

Title : Genomic Loci and Molecular Genetic Mechanisms For Hidradenitis Suppurativa. Personal Author(s) : Broadaway, K. Alaine;Sun, Quan;Edmiston, Sharon N;Currin, Kevin W;Vadlamudi, Swarooparani;Miller-Fleming, Tyne W;Shi, Yue;Fajgenbaum, Kristen;Melendez-Gonzalez, Maria;Bui, Helen;Blum, Franklin R;Westerkam, Linnea;Shams, Rayad;Mallela, Teja;Levitt, Brandt;Lin, Lan;Hao, Honglin;Memili, Aylin;Straub, Peter;Zhou, Wei;Harris, Kathleen Mullan;Martin, Alicia;Cox, Nancy J;Liu, Zhi;Thomas, Nancy E;Li, Yun;Mohlke, Karen L;Sayed, Christopher J; Published Date : July 2025 Pages in Document : 948-958 (22 pdf pages) Source : The British Journal of Dermatology, 2025, v. 193, no. 5 DOI : https://doi.org/10.1093/bjd/ljaf277 Journal Title : The British Journal of Dermatology
Broadaway, K. A., Sun, Q., Edmiston, S. N., Currin, K. W., Vadlamudi, S., Miller-Fleming, T. W., Shi, Y., Fajgenbaum, K., Melendez-Gonzalez, M., Bui, H., Blum, F. R., Westerkam, L., Shams, R., Mallela, T., Levitt, B., Lin, L., Hao, H., Memili, A., Straub, P., ... Sayed, C. J. (2025). Genomic Loci and Molecular Genetic Mechanisms For Hidradenitis Suppurativa. The British Journal of Dermatology, 193(5). https://doi.org/10.1093/bjd/ljaf277

Broadaway, K. Alaine, Quan Sun, Sharon N Edmiston, Kevin W Currin, Swarooparani Vadlamudi, Tyne W Miller-Fleming, and Yue Shi, et al.. "Genomic Loci and Molecular Genetic Mechanisms For Hidradenitis Suppurativa." The British Journal of Dermatology 193, no. 5 (2025). https://doi.org/10.1093/bjd/ljaf277.

Broadaway, K. Alaine, et al. "Genomic Loci and Molecular Genetic Mechanisms For Hidradenitis Suppurativa." The British Journal of Dermatology, vol. 193, no. 5, 2025. Stacks. https://doi.org/10.1093/bjd/ljaf277.
Export RIS Citation Information. TY - Journal Article AU - Broadaway, K. Alaine AU - Sun, Quan AU - Edmiston, Sharon N AU - Currin, Kevin W AU - Vadlamudi, Swarooparani AU - Miller-Fleming, Tyne W AU - Shi, Yue AU - Fajgenbaum, Kristen AU - Melendez-Gonzalez, Maria AU - Bui, Helen AU - Blum, Franklin R AU - Westerkam, Linnea AU - Shams, Rayad AU - Mallela, Teja AU - Levitt, Brandt AU - Lin, Lan AU - Hao, Honglin AU - Memili, Aylin AU - Straub, Peter AU - Zhou, Wei AU - Harris, Kathleen Mullan AU - Martin, Alicia AU - Cox, Nancy J AU - Liu, Zhi AU - Thomas, Nancy E AU - Li, Yun AU - Mohlke, Karen L AU - Sayed, Christopher J AB - Hidradenitis suppurativa (HS) is a common, chronic and debilitating inflammatory disease that most commonly affects intertriginous skin. Despite its high heritability, the genetic underpinnings of HS remain poorly understood. AB - To identify genetic signals associated with HS, determine genetic relationships with other diseases and investigate potential molecular genetic mechanisms. AB - We performed a genome-wide association meta-analysis of six studies, totalling 4540 patients with HS and > 1 million control participants, and identified genetic correlations with other common diseases. We integrated the HS data with expression quantitative trait loci from 10 trait-relevant tissues, epigenomic and transcriptomic data from human scalp, differential expression data from HS lesions vs. adjacent skin and mesenchymal Hi-C chromatin looping data. To identify functional noncoding variants, we performed transcriptional reporter assays for signals near KLF5 and SOX9. AB - We identified 11 significant HS signals across 7 loci: 4 corresponded to previously reported associations, 4 represented novel signals within known loci and 3 were signals in newly implicated loci. We identified significant genetic correlations between HS and other inflammatory conditions, particularly inflammatory bowel disease, rheumatoid arthritis, type 2 diabetes mellitus and asthma. We prioritized candidate genes for the 11 signals. The risk allele at KLF5 exhibited 10-fold greater transcriptional activity than the nonrisk allele, while risk alleles at SOX9 showed significantly reduced transcriptional activity. AB - Our results provide insights into potential genetic mechanisms underlying HS and suggest potential therapeutic targets for this challenging condition. AB - Author manuscript AN - cdc:261265 C4 - PMC12279254 DO - https://doi.org/10.1093/bjd/ljaf277 IS - 5 J2 - The British Journal of Dermatology KW - Hidradenitis Suppurativa KW - Quantitative Trait Loci KW - SOX9 Transcription Factor KW - Genome-Wide Association Study KW - Genetic Predisposition to Disease KW - Kruppel-Like Transcription Factors KW - Polymorphism, Single Nucleotide KW - Humans KW - Humans KW - Hidradenitis Suppurativa KW - Genome-Wide Association Study KW - Genetic Predisposition to Disease KW - Kruppel-Like Transcription Factors KW - SOX9 Transcription Factor KW - Polymorphism, Single Nucleotide KW - Quantitative Trait Loci LA - eng PY - 2025 T2 - The British Journal of Dermatology T2 - The British Journal of Dermatology, 2025, v. 193, no. 5 TI - Genomic Loci and Molecular Genetic Mechanisms For Hidradenitis Suppurativa. VL - 193 UR - https://stacks.cdc.gov/view/cdc/261265 ER -
Temporal Trends in Hepatitis C Incidence Among People Tested More Than Once in Georgia, 2017-23: a Nationwide, Retrospective Cohort.

Baliashvili, Davit ;

Shadaker, Shaun

September 2025 | The Lancet. Gastroenterology & Hepatology, 2025, v. 10, no. 9

Achieving low incidence is one of WHO's key targets for the elimination of hepatitis C virus (HCV) infection. As progress in Georgia's hepatitis C elimination programme moves the country closer to reaching this target, tracking new cases of hepatitis C has become a priority. We aimed to estimate temporal trends in hepatitis C incidence among people ...

10/09/2026

Supporting Files

Title : Temporal Trends in Hepatitis C Incidence Among People Tested More Than Once in Georgia, 2017-23: a Nationwide, Retrospective Cohort. Personal Author(s) : Baliashvili, Davit;Shadaker, Shaun;Furukawa, Nathan;Getia, Vladimer;Tsereteli, Maia;Symum, Hasan;Armstrong, Paige A;Tohme, Rania A;Handanagic, Senad; Published Date : September 2025 Pages in Document : 831-841 (23 pdf pages) Source : The Lancet. Gastroenterology & Hepatology, 2025, v. 10, no. 9 DOI : https://doi.org/10.1016/S2468-1253(25)00124-4 Journal Title : The Lancet. Gastroenterology & Hepatology
Baliashvili, D., Shadaker, S., Furukawa, N., Getia, V., Tsereteli, M., Symum, H., Armstrong, P. A., Tohme, R. A., & Handanagic, S. (2025). Temporal Trends in Hepatitis C Incidence Among People Tested More Than Once in Georgia, 2017-23: a Nationwide, Retrospective Cohort. The Lancet. Gastroenterology & Hepatology, 10(9). https://doi.org/10.1016/S2468-1253(25)00124-4

Baliashvili, Davit, Shaun Shadaker, Nathan Furukawa, Vladimer Getia, Maia Tsereteli, Hasan Symum, Paige A Armstrong, Rania A Tohme, and Senad Handanagic. "Temporal Trends in Hepatitis C Incidence Among People Tested More Than Once in Georgia, 2017-23: a Nationwide, Retrospective Cohort." The Lancet. Gastroenterology & Hepatology 10, no. 9 (2025). https://doi.org/10.1016/S2468-1253(25)00124-4.

Baliashvili, Davit, et al. "Temporal Trends in Hepatitis C Incidence Among People Tested More Than Once in Georgia, 2017-23: a Nationwide, Retrospective Cohort." The Lancet. Gastroenterology & Hepatology, vol. 10, no. 9, 2025. Stacks. https://doi.org/10.1016/S2468-1253(25)00124-4.
Export RIS Citation Information. TY - Journal Article AU - Baliashvili, Davit AU - Shadaker, Shaun AU - Furukawa, Nathan AU - Getia, Vladimer AU - Tsereteli, Maia AU - Symum, Hasan AU - Armstrong, Paige A AU - Tohme, Rania A AU - Handanagic, Senad AB - Achieving low incidence is one of WHO's key targets for the elimination of hepatitis C virus (HCV) infection. As progress in Georgia's hepatitis C elimination programme moves the country closer to reaching this target, tracking new cases of hepatitis C has become a priority. We aimed to estimate temporal trends in hepatitis C incidence among people who were tested more than once for hepatitis C in Georgia. AB - We conducted a retrospective cohort study in adults (aged ≥18 years) tested at least twice for antibodies against HCV (anti-HCV), with the first test being non-reactive, in Georgia from Jan 1, 2017, to Dec 31, 2023. Data were extracted from Georgian national hepatitis C screening and treatment databases on Jan 8, 2024. We calculated the incidence of anti-HCV seroconversion and current chronic HCV infections per 100 000 person-years and 95% CIs overall for 2017-23 and by year for 2017-22. For people who seroconverted but did not undergo testing to confirm current infection, we used multiple imputations to impute the status of current chronic HCV infection. To estimate the magnitude of change, we calculated incidence rate ratios (IRRs) with 95% CIs. AB - Among 1 264 181 adults with repeat anti-HCV testing during the study period, 519 936 (41·1%) were men and 744 245 (58·9%) were women. In total, 18 846 (1·5%) seroconverted to anti-HCV-reactive after a median follow-up time of 1025 days (IQR 503-1553). The overall incidence rate of anti-HCV seroconversion was 514 cases per 100 000 person-years (95% CI 506-521). The overall estimated incidence rate of current chronic HCV infection was 293 cases per 100 000 person-years (288-299). The annual incidence rate of anti-HCV seroconversion was 3·7 times lower in 2022 than in 2017, declining from 1399 cases per 100 000 person-years (1346-1454) to 377 cases per 100 000 person-years (361-394; IRR 0·27 [95% CI 0·25-0·29]). The annual incidence rate of chronic HCV infection was 4·6 times lower in 2022 than in 2017, declining from 935 cases per 100 000 person-years (892-981) to 205 cases per 100 000 person-years (193-217; IRR 0·22 [95% CI 0·20-0·24]). AB - We found a high but decreasing incidence rate of hepatitis C in Georgia among people tested more than once. The country should scale up preventive interventions to reduce incidence further and reach elimination targets. AB - None. AB - For the Georgian translation of the abstract see Supplementary Materials section. AB - Author manuscript AN - cdc:261264 C4 - PMC12313192 DO - https://doi.org/10.1016/S2468-1253(25)00124-4 IS - 9 J2 - The Lancet. Gastroenterology & Hepatology KW - Female KW - Hepatitis C, Chronic KW - Mass Screening KW - Young Adult KW - Retrospective Studies KW - Seroconversion KW - Incidence KW - Hepatitis C KW - Male KW - Humans KW - Hepatitis C Antibodies KW - Middle Aged KW - Adult KW - Georgia (Republic) KW - Hepacivirus KW - Humans KW - Retrospective Studies KW - Male KW - Female KW - Incidence KW - Adult KW - Middle Aged KW - Georgia (Republic) KW - Hepatitis C Antibodies KW - Hepatitis C, Chronic KW - Hepatitis C KW - Seroconversion KW - Hepacivirus KW - Mass Screening KW - Young Adult LA - eng PY - 2025 T2 - The Lancet. Gastroenterology & Hepatology T2 - The Lancet. Gastroenterology & Hepatology, 2025, v. 10, no. 9 TI - Temporal Trends in Hepatitis C Incidence Among People Tested More Than Once in Georgia, 2017-23: a Nationwide, Retrospective Cohort. VL - 10 UR - https://stacks.cdc.gov/view/cdc/261264 ER -
Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus.

Prasad, Mona ;

Sandoval, Grecio J.

February 2026 | Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 2026, v. 81, no. 6

In this study, a single hepatitis C virus (HCV) RNA at 2-6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%-96.3% and 100% and 95% CI, 98.8%-100%, respectively) in identifying perinatal transmission of HCV. No cases of perinatal infection requiring treatment were missed.

10/09/2026

Supporting Files

Title : Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus. Personal Author(s) : Prasad, Mona;Sandoval, Grecio J.;Saade, George R.;Hughes, Brenna L.;Clifton, Rebecca G.;Reddy, Uma M.;Bartholomew, Anna;Salazar, Ashley;Chien, Edward K.;Tita, Alan T. N.;Thorp, John M.;Metz, Torri D.;Wapner, Ronald J.;Sabharwal, Vishakha;Simhan, Hyagriv N.;Swamy, Geeta K.;Heyborne, Kent D.;Sibai, Baha M.;Grobman, William A.;El-Sayed, Yasser Y.;Casey, Brian M.;Parry, Samuel;Macones, George A.; Published Date : February 2026 Pages in Document : 1102-1105 (7 pdf pages) Source : Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 2026, v. 81, no. 6 DOI : https://doi.org/10.1093/cid/ciaf266 Journal Title : Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America
Prasad, M., Sandoval, G. J., Saade, G. R., Hughes, B. L., Clifton, R. G., Reddy, U. M., Bartholomew, A., Salazar, A., Chien, E. K., Tita, A. T. N., Thorp, J. M., Metz, T. D., Wapner, R. J., Sabharwal, V., Simhan, H. N., Swamy, G. K., Heyborne, K. D., Sibai, B. M., Grobman, W. A., ... Macones, G. A. (2026). Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 81(6). https://doi.org/10.1093/cid/ciaf266

Prasad, Mona, Grecio J. Sandoval, George R. Saade, Brenna L. Hughes, Rebecca G. Clifton, Uma M. Reddy, and Anna Bartholomew, et al.. "Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus." Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America 81, no. 6 (2026). https://doi.org/10.1093/cid/ciaf266.

Prasad, Mona, et al. "Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus." Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, vol. 81, no. 6, 2026. Stacks. https://doi.org/10.1093/cid/ciaf266.
Export RIS Citation Information. TY - Journal Article AU - Prasad, Mona AU - Sandoval, Grecio J. AU - Saade, George R. AU - Hughes, Brenna L. AU - Clifton, Rebecca G. AU - Reddy, Uma M. AU - Bartholomew, Anna AU - Salazar, Ashley AU - Chien, Edward K. AU - Tita, Alan T. N. AU - Thorp, John M. AU - Metz, Torri D. AU - Wapner, Ronald J. AU - Sabharwal, Vishakha AU - Simhan, Hyagriv N. AU - Swamy, Geeta K. AU - Heyborne, Kent D. AU - Sibai, Baha M. AU - Grobman, William A. AU - El-Sayed, Yasser Y. AU - Casey, Brian M. AU - Parry, Samuel AU - Macones, George A. AB - In this study, a single hepatitis C virus (HCV) RNA at 2-6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%-96.3% and 100% and 95% CI, 98.8%-100%, respectively) in identifying perinatal transmission of HCV. No cases of perinatal infection requiring treatment were missed. AB - Author manuscript AN - cdc:261263 C4 - PMC12285734 DO - https://doi.org/10.1093/cid/ciaf266 IS - 6 J2 - Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America KW - Pregnancy KW - Female KW - RNA, Viral KW - Sensitivity and Specificity KW - Polymerase Chain Reaction KW - Infant, Newborn KW - Pregnancy Complications, Infectious KW - Infectious Disease Transmission, Vertical KW - Infant KW - Hepatitis C KW - Male KW - Humans KW - Hepacivirus KW - Adult KW - hepatitis C virus KW - HCV KW - perinatal transmission KW - PCR KW - pediatric screening KW - Humans KW - Infectious Disease Transmission, Vertical KW - Hepatitis C KW - Hepacivirus KW - Female KW - Infant, Newborn KW - RNA, Viral KW - Sensitivity and Specificity KW - Pregnancy KW - Polymerase Chain Reaction KW - Infant KW - Pregnancy Complications, Infectious KW - Male KW - Adult LA - eng PY - 2026 T2 - Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America T2 - Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 2026, v. 81, no. 6 TI - Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus. VL - 81 UR - https://stacks.cdc.gov/view/cdc/261263 ER -
Like Everybody Else : Adolescent Perceptions of Safe, Independent Driving With a CHD.

DiFusco, Leigh Ann ;

Solomon, Rachel A.

July 2025 | Cardiology in the Young, 2025, v. 35, no. 7

The impact of CHD on safe driving for adolescents is currently unknown. A prospective, qualitative descriptive study was conducted among adolescents with CHD to describe perceived barriers, facilitators, and impacts of CHD on safe, independent driving among adolescents.Twenty-eight adolescents aged 15-19 years with CHD participated in virtual, semi ...

10/09/2026

Supporting Files

Title : Like Everybody Else : Adolescent Perceptions of Safe, Independent Driving With a CHD. Personal Author(s) : DiFusco, Leigh Ann;Solomon, Rachel A.;Lee, Lindsey H.;McIntosh, C. Ward;McDonald, Catherine C.; Published Date : July 2025 Pages in Document : 1388-1393 (11 pdf pages) Source : Cardiology in the Young, 2025, v. 35, no. 7 DOI : https://doi.org/10.1017/S1047951125100784 Journal Title : Cardiology in the Young
DiFusco, L. A., Solomon, R. A., Lee, L. H., McIntosh, C. W., & McDonald, C. C. (2025). Like Everybody Else : Adolescent Perceptions of Safe, Independent Driving With a CHD. Cardiology in the Young, 35(7). https://doi.org/10.1017/S1047951125100784

DiFusco, Leigh Ann, Rachel A. Solomon, Lindsey H. Lee, C. Ward McIntosh, and Catherine C. McDonald. "Like Everybody Else : Adolescent Perceptions of Safe, Independent Driving With a CHD." Cardiology in the Young 35, no. 7 (2025). https://doi.org/10.1017/S1047951125100784.

DiFusco, Leigh Ann, et al. "Like Everybody Else : Adolescent Perceptions of Safe, Independent Driving With a CHD." Cardiology in the Young, vol. 35, no. 7, 2025. Stacks. https://doi.org/10.1017/S1047951125100784.
Export RIS Citation Information. TY - Journal Article AU - DiFusco, Leigh Ann AU - Solomon, Rachel A. AU - Lee, Lindsey H. AU - McIntosh, C. Ward AU - McDonald, Catherine C. AB - The impact of CHD on safe driving for adolescents is currently unknown. A prospective, qualitative descriptive study was conducted among adolescents with CHD to describe perceived barriers, facilitators, and impacts of CHD on safe, independent driving among adolescents. AB - Twenty-eight adolescents aged 15-19 years with CHD participated in virtual, semi-structured interviews in 2023. Adolescent interview data were analysed with conventional content analysis refined by Theoretical Domains Framework in NVivo software. AB - Mean participant age was 16.4 ± 0.23 years (57% male). Single ventricle physiology (25%) and septal defects (32%) were prevalent diagnoses among the study population. Most participants (92%) did not have driving restrictions. AB - Driving as a normal rite of passage for adolescents with CHD; and confident-but curious-about the impacts of CHD on driving. Adolescents felt confident that driving is not impacted by CHD. They were curious about the likelihood of cardiovascular emergencies and related symptoms while driving. Perceived barriers and facilitators to safe, independent driving were like what has been described in published literature among adolescents without CHD. AB - These findings celebrate the normalcy of driving during adolescence and reveal curiosities about the impacts of stress, anxiety, fatigue, and risks of heart attack and stroke on driving. Adolescents may look to CHD healthcare providers to help them learn about driving. These findings may inform the development of tools to facilitate meaningful conversations with adolescents regarding driving safety as part of the transition to adult CHD care. AB - Author manuscript AN - cdc:261262 C4 - PMC12456235 DO - https://doi.org/10.1017/S1047951125100784 IS - 7 J2 - Cardiology in the Young KW - Adolescent KW - Automobile Driving KW - Female KW - Qualitative Research KW - Heart Defects, Congenital KW - Prospective Studies KW - Male KW - Humans KW - Young Adult KW - Interviews as Topic KW - Perception KW - Adolescent KW - CHD KW - driver's license KW - learner's permit KW - motor vehicle KW - driving behaviours KW - Humans KW - Adolescent KW - Male KW - Automobile Driving KW - Female KW - Heart Defects, Congenital KW - Prospective Studies KW - Young Adult KW - Qualitative Research KW - Perception KW - Interviews as Topic LA - eng PY - 2025 T2 - Cardiology in the Young T2 - Cardiology in the Young, 2025, v. 35, no. 7 TI - Like Everybody Else : Adolescent Perceptions of Safe, Independent Driving With a CHD. VL - 35 UR - https://stacks.cdc.gov/view/cdc/261262 ER -
Breathing Hazards: Perspective on the Adverse Health Effects of Organophosphate Flame Retardants.

Solan, Megan E. ;

Goetzinger, Emma G.

May 2025 | Journal of Hazardous Materials Advances, 2025, v. 18

Since the 1970s, flame retardants have been applied to consumer and industrial products to prevent combustion and the spread of fires, with polybrominated diphenyl ethers (PBDEs) being the most prevalent. However, due to environmental and human health concerns, the use of PBDEs was phased out and nearly eliminated by the early 2000s. As a safer alt ...

10/09/2026

Supporting Files

Title : Breathing Hazards: Perspective on the Adverse Health Effects of Organophosphate Flame Retardants. Personal Author(s) : Solan, Megan E.;Goetzinger, Emma G.;Sampath, Vanitha;Park, Jin-Ah; Published Date : May 2025 Pages in Document : 19 pdf pages Source : Journal of Hazardous Materials Advances, 2025, v. 18 DOI : https://doi.org/10.1016/j.hazadv.2025.100744 Journal Title : Journal of Hazardous Materials Advances
Solan, M. E., Goetzinger, E. G., Sampath, V., & Park, J. A. (2025). Breathing Hazards: Perspective on the Adverse Health Effects of Organophosphate Flame Retardants. Journal of Hazardous Materials Advances, 18. https://doi.org/10.1016/j.hazadv.2025.100744

Solan, Megan E., Emma G. Goetzinger, Vanitha Sampath, and Jin-Ah Park. "Breathing Hazards: Perspective on the Adverse Health Effects of Organophosphate Flame Retardants." Journal of Hazardous Materials Advances 18 (2025). https://doi.org/10.1016/j.hazadv.2025.100744.

Solan, Megan E., et al. "Breathing Hazards: Perspective on the Adverse Health Effects of Organophosphate Flame Retardants." Journal of Hazardous Materials Advances, vol. 18, 2025. Stacks. https://doi.org/10.1016/j.hazadv.2025.100744.
Export RIS Citation Information. TY - Journal Article AU - Solan, Megan E. AU - Goetzinger, Emma G. AU - Sampath, Vanitha AU - Park, Jin-Ah AB - Since the 1970s, flame retardants have been applied to consumer and industrial products to prevent combustion and the spread of fires, with polybrominated diphenyl ethers (PBDEs) being the most prevalent. However, due to environmental and human health concerns, the use of PBDEs was phased out and nearly eliminated by the early 2000s. As a safer alternative to PBDEs, organophosphate flame retardants (OPFRs) were proposed as they were believed to have a shorter half-life and increased degradation rate compared to PBDEs. OPFRs are widely used in consumer products, including electronics, textiles, and car interiors. The dusts produced from product usage results in OPFR exposure through inhalation, ingestion, and dermal absorption. Despite dusts being a major exposure source, the effects of inhalation and subsequent effects on lung health remain understudied. A few AB - studies have demonstrated lung inflammation and airway hyperresponsiveness as consequences of OPFR inhalation exposure and these findings are supported by AB - studies. However, significant gaps remain in our understanding of OPFR exposure and the implications for public health. Conducting additional epidemiological studies, alongside AB - studies and the development of PBPK/TK models, can significantly enhance the power of hazard assessment for inhalation exposure in humans. This review article discusses the sources and routes of exposure to OPFRs and their adverse health effects, emphasizing inhalation toxicology. Furthermore, we identify critical gaps in current knowledge regarding the health risks posed by OPFRs and propose future research directions to explore their adverse environmental and human health consequences. AB - Author manuscript AN - cdc:261261 C4 - PMC12252992 DO - https://doi.org/10.1016/j.hazadv.2025.100744 J2 - Journal of Hazardous Materials Advances KW - Half-Life KW - Pneumonia KW - Textiles KW - Flame Retardants KW - Epidemiologic Studies KW - Respiratory Hypersensitivity KW - Halogenated Diphenyl Ethers KW - Organophosphates KW - Inhalation Exposure KW - Eating KW - Automobiles KW - Electronics KW - Public Health KW - Humans KW - Lung KW - Organophosphate flame retardants KW - Respiratory toxicity KW - Inhalation exposure KW - Climate change KW - Humans KW - Automobiles KW - Flame Retardants KW - Half-Life KW - Halogenated Diphenyl Ethers KW - Inhalation Exposure KW - Public Health KW - Respiratory Hypersensitivity KW - Epidemiologic Studies KW - Pneumonia KW - Organophosphates KW - Electronics KW - Eating KW - Textiles KW - Lung LA - eng PY - 2025 T2 - Journal of Hazardous Materials Advances T2 - Journal of Hazardous Materials Advances, 2025, v. 18 TI - Breathing Hazards: Perspective on the Adverse Health Effects of Organophosphate Flame Retardants. VL - 18 UR - https://stacks.cdc.gov/view/cdc/261261 ER -
Evaluation of Swabbing Methods For Culture and Non-culture-based Recovery of Multidrug-resistant Organisms From Environmental Surfaces.

Babiker, Ahmed ;

Van Riel, Julia

August 2025 | Infection Control and Hospital Epidemiology, 2025, v. 46, no. 8

Sponge-Sticks (SS) and ESwabs are frequently utilized for detection of multidrug-resistant organisms (MDROs) in the environment. Head-to-head comparisons of SS and ESwabs across recovery endpoints are limited.We compared MDRO culture and non-culture-based recovery from (1) ESwabs, (2) cellulose-containing SS (CS), and (3) polyurethane-containing SS ...

10/09/2026

Supporting Files

Title : Evaluation of Swabbing Methods For Culture and Non-culture-based Recovery of Multidrug-resistant Organisms From Environmental Surfaces. Personal Author(s) : Babiker, Ahmed;Van Riel, Julia;Lohsen, Sarah;Page, Alex;Strudwick, Amanda;Wilber, Eli;Woodworth, Michael;Satola, Sarah; Published Date : August 2025 Pages in Document : 837-844 (16 pdf pages) Source : Infection Control and Hospital Epidemiology, 2025, v. 46, no. 8 DOI : https://doi.org/10.1017/ice.2025.10214 Journal Title : Infection Control and Hospital Epidemiology
Babiker, A., Van Riel, J., Lohsen, S., Page, A., Strudwick, A., Wilber, E., Woodworth, M., & Satola, S. (2025). Evaluation of Swabbing Methods For Culture and Non-culture-based Recovery of Multidrug-resistant Organisms From Environmental Surfaces. Infection Control and Hospital Epidemiology, 46(8). https://doi.org/10.1017/ice.2025.10214

Babiker, Ahmed, Julia Van Riel, Sarah Lohsen, Alex Page, Amanda Strudwick, Eli Wilber, Michael Woodworth, and Sarah Satola. "Evaluation of Swabbing Methods For Culture and Non-culture-based Recovery of Multidrug-resistant Organisms From Environmental Surfaces." Infection Control and Hospital Epidemiology 46, no. 8 (2025). https://doi.org/10.1017/ice.2025.10214.

Babiker, Ahmed, et al. "Evaluation of Swabbing Methods For Culture and Non-culture-based Recovery of Multidrug-resistant Organisms From Environmental Surfaces." Infection Control and Hospital Epidemiology, vol. 46, no. 8, 2025. Stacks. https://doi.org/10.1017/ice.2025.10214.
Export RIS Citation Information. TY - Journal Article AU - Babiker, Ahmed AU - Van Riel, Julia AU - Lohsen, Sarah AU - Page, Alex AU - Strudwick, Amanda AU - Wilber, Eli AU - Woodworth, Michael AU - Satola, Sarah AB - Sponge-Sticks (SS) and ESwabs are frequently utilized for detection of multidrug-resistant organisms (MDROs) in the environment. Head-to-head comparisons of SS and ESwabs across recovery endpoints are limited. AB - We compared MDRO culture and non-culture-based recovery from (1) ESwabs, (2) cellulose-containing SS (CS), and (3) polyurethane-containing SS (PCS). AB - Known quantities of each MDRO were pipetted on a stainless-steel surface and swabbed by each method. Samples were processed, cultured, and underwent colony counting. DNA was extracted from sample eluates, quantified, and underwent metagenomic next-generation sequencing (mNGS). MDROs underwent whole genome sequencing (WGS). MDRO recovery from paired patient perirectal and PCS-collected environmental samples from clinical studies was determined. AB - Laboratory experiment, tertiary medical center, and long-term acute care facility. AB - Culture-based recovery varied across MDRO taxa, it was highest for vancomycin-resistant AB - and lowest for carbapenem-resistant AB - (CRPA). Culture-based recovery was significantly higher for SS compared to ESwabs except for CRPA, where all methods performed poorly. Nucleic acid recovery varied across methods and MDRO taxa. Integrated WGS and mNGS analysis resulted in successful detection of antimicrobial resistance genes, construction of high-quality metagenome-assembled genomes, and detection of MDRO genomes in environmental metagenomes across methods. In paired patient and environmental samples, multidrug-resistant AB - MDRP) environmental recovery was notably poor (0/123), despite detection of MDRP in patient samples (20/123). AB - Our findings support the use of SS for the recovery of MDROs. Pitfalls of each method should be noted. Method selection should be driven by MDRO target and desired endpoint. AB - Author manuscript AN - cdc:261260 C4 - PMC12422522 DO - https://doi.org/10.1017/ice.2025.10214 IS - 8 J2 - Infection Control and Hospital Epidemiology KW - Specimen Handling KW - Drug Resistance, Multiple, Bacterial KW - Vancomycin-Resistant Enterococci KW - Humans KW - Environmental Microbiology KW - Whole Genome Sequencing KW - Environmental contamination KW - Environmental sampling KW - healthcare transmission KW - MDROs KW - CRPA KW - CRAB KW - ESBL KW - MRSA KW - VRE KW - Humans KW - Drug Resistance, Multiple, Bacterial KW - Specimen Handling KW - Whole Genome Sequencing KW - Environmental Microbiology KW - Vancomycin-Resistant Enterococci LA - eng PY - 2025 T2 - Infection Control and Hospital Epidemiology T2 - Infection Control and Hospital Epidemiology, 2025, v. 46, no. 8 TI - Evaluation of Swabbing Methods For Culture and Non-culture-based Recovery of Multidrug-resistant Organisms From Environmental Surfaces. VL - 46 UR - https://stacks.cdc.gov/view/cdc/261260 ER -

Previous Page Previous

1261 - 1280 / 1996

Next Page Next

Found an issue?

Send us an email at: publishinghd@cdc.gov