The study of in vivo quantification of aluminum (Al) in human bone with a compact DD generator-based neutron activation analysis (NAA) system

Byrne, Patrick; Mostafaei, Farshad; Liu, Yingzi; Blake, Scott P; Koltick, David; Nie, Linda H

doi:10.1088/0967-3334/37/5/649

i

The study of in vivo quantification of aluminum (Al) in human bone with a compact DD generator-based neutron activation analysis (NAA) system

Supporting Files

5 2016
By Byrne, Patrick ; Mostafaei, Farshad ; Liu, Yingzi
http://dx.doi.org/10.1088/0967-3334/37/5/649
Available in CDC Stacks on 2021-01-04T00:00:00Z

File Language:

English

Details

Journal Article:

Physiol Meas
Personal Author:

Byrne, Patrick ; Mostafaei, Farshad ; Liu, Yingzi ; Blake, Scott P ; Koltick, David ; Nie, Linda H
Description:

The feasibility and methodology of using a compact DD generator-based neutron activation analysis system to measure aluminum in hand bone has been investigated. Monte Carlo simulations were used to simulate the moderator, reflector, and shielding assembly and to estimate the radiation dose. A high purity germanium (HPGe) detector was used to detect the Al gamma ray signals. The minimum detectable limit (MDL) was found to be 11.13 μg g(-1) dry bone (ppm). An additional HPGe detector would improve the MDL by a factor of 1.4, to 7.9 ppm. The equivalent dose delivered to the irradiated hand was calculated by Monte Carlo to be 11.9 mSv. In vivo bone aluminum measurement with the DD generator was found to be feasible among general population with an acceptable dose to the subject.
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Keywords:
Source:

Physiol Meas. 37(5):649-660
DOI:

http://dx.doi.org/10.1088/0967-3334/37/5/649
Pubmed ID:

27093035
Pubmed Central ID:

PMC7781013
Document Type:

Text ; Journal Article
Funding:

R21 OH010044/OH/NIOSH CDC HHSUnited States/ ; R21 OH010700/OH/NIOSH CDC HHSUnited States/
Genre:

Journal Article
Volume:

37
Issue:

5
Download URL:

https://stacks.cdc.gov/view/cdc/99953/cdc_99953_DS1.pdf
File Type:

[PDF - 842.21 KB]
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha-512:51af5dcaf0b0dc4f3516fa089642cea6cfc5b913ca258e20fb31b6675cc28714a95e24017ec182270520a1b6b6915af64d8714a35b444103eb53157f66a0228e

File Language:

English

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