Details:

Alternative Title:
Sci Total Environ
Publisher's site:
http://dx.doi.org/10.1016/j.scitotenv.2020.144010
Personal Author:
Zarus, Gregory M. ; Muianga, Custodio ; Hunter, Candis ; Pappas, R. Steven
Zarus, Gregory M. ; Muianga, Custodio ; Hunter, Candis ; Pappas, R. Steven Less -
Description:
Plastic debris have been shown to degenerate to particle sizes that can be transported in air, water, and food. Small particles are documented to enter and exit our bodies and translocate to and from some internal organs. Health effects on respiratory, hepatic, immune, and gastrointestinal systems have been reported in humans and other mammals in response to elevated particle or fiber exposures. These health effects differed by plastic type and size, and there was evidence of dose response for a few health endpoints. We conducted a systematic word search and reviewed published literature to identify microplastic and nanoplastic studies that quantified exposure via the ingestion, inhalation, and subcutaneous absorption (not dermal) exposure pathways; identified translocation, internal dose, and associations with health effects and markers related to exposures to specific sizes and types of plastics. We identified the data gaps in relating exposure data to health effects and biomarkers, most notably the lack of characterization of plastic particles and fibers smaller than 10 μm in most media.
Subject:
[+]
Animals
Article
Biomarkers
Environmental Exposures
Environmental Monitoring
Health Effects
Humans
Microplastics
Nanoplastics
Particle Size
Plastics
Water Pollutants, Chemical
Microplastics

Source:
Sci Total Environ. 756:144010
Pubmed ID:
33310215
Pubmed Central ID:
PMC7775266
Document Type:
Journal Article
Funding:
CC999999/ImCDC/Intramural CDC HHSUnited States/
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:85ff941fb33cc83d6f8cb24cce8c769d6127ce743b14f1eadf6f494e9cefe834
File Type:

Supporting Files

• 	nihms-1655286-f0001.jpg	jpeg
  	nihms-1655286.nxml	xml

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