Birth and Infant Outcomes Following Laboratory-Confirmed SARS-CoV-2 Infection in Pregnancy — SET-NET, 16 Jurisdictions, March 29–October 14, 2020

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Woodworth, Kate R. ; Olsen, Emily O’Malley ; Neelam, Varsha ; Lewis, Elizabeth L. ; Galang, Romeo R. ; Oduyebo, Titilope ; Aveni, Kathryn ; Yazdy, Mahsa M. ; Harvey, Elizabeth ; Longcore, Nicole D. ; Barton, Jerusha ; Fussman, Chris ; Siebman, Samantha ; Lush, Mamie ; Patrick, Paul H. ; Halai, Umme-Aiman ; Valencia-Prado, Miguel ; Orkis, Lauren ; Sowunmi, Similoluwa ; Schlosser, Levi ; Khuwaja, Salma ; Read, Jennifer S. ; Hall, Aron J. ; Meaney-Delman, Dana ; Ellington, Sascha R. ; Gilboa, Suzanne M. ; Tong, Van T. ; Delaney, Augustina ; Hsia, Jason ; King, Kellianne ; Perez, Mirna ; Reynolds, Megan ; Riser, Aspen ; Rivera, Maria ; Sancken, Christina ; Sims, John ; Smoots, Ashley ; Snead, Margaret ; Strid, Penelope ; Yowe-Conley, Tineka ; Zambrano, Laura ; Zapata, Lauren ; Manning, Susan ; Burkel, Veronica ; Akosa, Amanda ; Bennett, Carolyne ; Griffin, Isabel ; Nahabedian, John ; Newton, Suzanne ; Roth, Nicole M. ; Shinde, Neha ; Whitehouse, Erin ; Chang, Daniel ; Fox, Charise ; Mohamoud, Yousra ; Whitehill, Florence
• Corporate Authors:
  CDC COVID-19 Response Pregnancy and Infant Linked Outcomes Team ; COVID-19 Pregnancy and Infant Linked Outcomes Team (PILOT)
• Description:
  Pregnant women with coronaVirus disease 2019 (COVID-19) are at increased risk for severe illness and might be at risk for preterm birth (1-3). The full impact of infection with SARS-CoV-2, the Virus that causes COVID-19, in pregnancy is unknown. Public health jurisdictions report information, including pregnancy status, on confirmed and probable COVID-19 cases to CDC through the National Notifiable Diseases Surveillance System.* Through the Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET), 16 jurisdictions collected supplementary information on pregnancy and infant outcomes among 5,252 women with laboratory-confirmed SARS-CoV-2 infection reported during March 29-October 14, 2020. Among 3,912 live births with known gestational age, 12.9% were preterm (<37 weeks), higher than the reported 10.2% among the general U.S. population in 2019 (4). Among 610 infants (21.3%) with reported SARS-CoV-2 test results, perinatal infection was infrequent (2.6%) and occurred primarily among infants whose mother had SARS-CoV-2 infection identified within 1 week of delivery. Because the majority of pregnant women with COVID-19 reported thus far experienced infection in the third trimester, ongoing Surveillance is needed to assess effects of infections in early pregnancy, as well the longer-term outcomes of exposed infants. These findings can inform neonatal tTesting recommendations, clinical practice, and public health action and can be used by health care providers to counsel pregnant women on the risks of SARS-CoV-2 infection, including preterm births. Pregnant women and their household members should follow recommended infection Prevention measures, including wearing a mask, social distancing, and frequent handwashing when going out or interacting with others or if there is a person within the household who has had exposure to COVID-19.|.
• Subjects:
  Abortion, Spontaneous Adult BetacoronaVirus Clinical Laboratory Techniques CoronaVirus Infections COVID-19 Female Humans Infant, Newborn Infectious Disease Transmission, Vertical Laboratories Pandemics Pneumonia, Viral Pregnancy Pregnancy Complications, Infectious Pregnancy Outcome Premature Birth Risk Assessment Young Adult

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• Source:
  MMWR Morbidity Mortal Weekly Rep. 69(44):1635-1640
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  33151917
• Pubmed Central ID:
  PMC7643898
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  6 pdf pages
• Volume:
  69
• Issue:
  44
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:bab51d63daa7b87482b2473ce09e2dd8f00b5b43dd7989a5c63e1a012561acaf266d50c3ab61e98c29ead6f47c4174471935d727d3f00ba3625aa4bda9634dd8
• Download URL:
  https://stacks.cdc.gov/view/cdc/97454/cdc_97454_DS1.pdf
• File Type:
  [PDF - 117.75 KB ]