Rapid diagnostic tests to address challenges for global measles surveillance

Details

• Alternative Title:
  Curr Opin Virol
• Personal Author:
  Brown, David W ; Warrener, Lenesha ; Scobie, Heather M ; Donadel, Morgane ; Waku-Kouomou, Diane ; Mulders, Mick N ; Rota, Paul A
• Description:
  Recently, a lateral flow rapid diagnostic test (RDT) with good accuracy has been described. This test enables measles specific IgM antibody detection in serum, capillary blood and oral fluid. RDTs have the potential to transform measles surveillance by allowing real-time case confirmation outside of central/regional laboratories and by facilitating a timely public health response. Measles virus genes can also be amplified and sequenced consistently from dried IgM-positive RDTs stored outside of cold chain, which will enable more complete virologic surveillance. Critical questions remain regarding operational use of RDTs as part of global measles surveillance. Projects to evaluate RDT use as part of national surveillance programs and to commercialize the RDT are underway.
• Subjects:
  Diagnostic Tests, Routine Epidemiological Monitoring Global Health Humans Measles Measles Virus
• Source:
  Curr Opin Virol. 41:77-84
• Pubmed ID:
  32615510
• Pubmed Central ID:
  PMC7492366
• Document Type:
  Journal Article
• Funding:
  001/WHO_/World Health OrganizationInternational/ ; CC999999/Intramural CDC HHSUnited States/
• Volume:
  41
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:722a8efc8c06024ebd1f5dfee09451e1794c78e2ccb05d053dadb574f237691335b305cba6b226232dc57dcaf5b26ada3af557490eb1677ee82fec581844476e
• Download URL:
  https://stacks.cdc.gov/view/cdc/93851/cdc_93851_DS1.pdf
• File Type:
  [PDF - 732.83 KB ]