283. Potentially Achievable Hepatitis A Vaccination Coverage with Simultaneous Administration of Vaccines Among Young Children in the United States

Details

• Alternative Title:
  Open Forum Infect Dis
• Personal Author:
  Zhao, Zhen ; Hill, Holly ; Elam-Evans, Laurie ; Chen, Michael ; Singleton, James A
• Description:
  Background
  
  The Advisory Committee on Immunization Practices recommends simultaneous administration of all age-appropriate doses of vaccines. We estimated the vaccination coverage for ≥2 doses of hepatitis A vaccine (≥2 HepA) that could have been achieved if opportunities for simultaneous administration with other recommended childhood vaccines had not been missed.
  
  Methods
  
  We analyzed National Immunization Survey-Child data for 2008–2017 in the United States. We defined potentially achievable ≥2 HepA coverage by age 24 months as the possible coverage if opportunities for simultaneous administration with other age-appropriate doses of vaccines for children by age 24 months had not been missed. We compared potentially achievable vaccination coverage to reported ≥2 HepA vaccination coverage by birth years 2007 to 2015. For children born in 2015, we stratified estimates by state and by selected socio-demographic factors. Both potentially achievable and reported ≥2 HepA coverage were evaluated using a Kaplan–Meier survival procedure to account for censoring of vaccination status.
  
  Results
  
  Compared with reported vaccination coverage, potentially achievable coverage for ≥2 HepA was at least 10 percentage points higher across birth years 2007 to 2015 and would have surpassed the 85% target of Healthy People 2020 for children born in 2015 (Figure 1). For the 2015 birth cohort, potentially achievable ≥2 HepA coverage exceeded the 85% Healthy People 2020 target in ten states (Figure 2). In addition, potentially achievable vaccination coverage was higher than reported coverage across all selected socio-demographic factors, with differences ranging from 20.1 percentage-points (private insurance only) to 31.7 percentage-points (non-Hispanic Black) (Table 1).
  
  Conclusion
  
  Potentially achievable coverage with ≥2 HepA consistently exceeded reported coverage for children from nine recent birth cohorts and across all selected socio-demographic characteristics. Coverage could increase substantially if missed opportunities were eliminated. Evidence-based interventions such as establishment of standing orders, use of provider reminders, and use of immunization information systems are recommended to increase HepA coverage among young children.
  
  Disclosures
  
  All authors: No reported disclosures.
  
  
• Subjects:
  Abstracts
• Source:
  Open Forum Infect Dis. 2019; 6(Suppl 2):S154-S155
• Pubmed Central ID:
  PMC6809844
• Document Type:
  Journal Article
• Volume:
  6
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:6bec8d0505fb509ae9d9f3aefba5082a7e8f869ad097d89384d7bf4ef28d3294
• Download URL:
  https://stacks.cdc.gov/view/cdc/93670/cdc_93670_DS1.pdf
• File Type:
  [PDF - 1.39 MB ]