Details:

Personal Author:
Kim, Lindsay ; Whitaker, Michael ; O’Halloran, Alissa ; Kambhampati, Anita ; Chai, Shua J. ; ... More +
Kim, Lindsay ; Whitaker, Michael ; O’Halloran, Alissa ; Kambhampati, Anita ; Chai, Shua J. ; Reingold, Arthur ; Armistead, Isaac ; Kawasaki, Breanna ; Meek, James ; Yousey-Hindes, Kimberly ; Anderson, Evan J. ; Openo, Kyle P. ; Weigel, Andy ; Ryan, Patricia ; Monroe, Maya L. ; Fox, Kimberly ; Kim, Sue ; Lynfield, Ruth ; Bye, Erica ; Davis, Sarah Shrum ; Smelser, Chad ; Barney, Grant ; Spina, Nancy L. ; Bennett, Nancy M. ; Felsen, Christina B. ; Billing, Laurie M. ; Shiltz, Jessica ; Sutton, Melissa ; West, Nicole ; Talbot, H. Keipp ; Schaffner, William ; Risk, Ilene ; Price, Andrea ; Brammer, Lynnette ; Fry, Alicia M. ; Hall, Aron J. ; Langley, Gayle E. ; Garg, Shikha Less -
Corporate Authors:
COVID-NET Surveillance Team. ; CDC COVID-NET Team. ; United States. Public Health Service. ; Eagle Global Scientific. ; Cherokee Nation Assurance. ; ... More +
COVID-NET Surveillance Team. ; CDC COVID-NET Team. ; United States. Public Health Service. ; Eagle Global Scientific. ; Cherokee Nation Assurance. ; California Emerging Infections Program. ; University of California, Berkeley. School of Public Health. ; University of Colorado Anschutz Medical Campus. School of Medicine. ; Colorado. Department of Public Health & Environment. ; Yale University. School of Public Health.Connecticut Emerging Infections Program. ; Emory University. School of Medicine. Department of Medicine. Emory University. School of Medicine. Department of Pediatrics. ; Iowa. Department of Public Health. ; Maryland. Department of Health. ; Michigan. Department of Health and Human Services. ; Minnesota. Department of Health. ; New Mexico Emerging Infections Program, Albuquerque, New Mexico ; New Mexico. Department of Health. ; New York (State). Department of Health. ; University of Rochester. School of Medicine and Dentistry. ; Ohio. Department of Health. ; Oregon Health Authority. Public Health Division. ; Vanderbilt University. Medical Center. ; Veterans Affairs Medical Center (Atlanta, Ga.). Emerging Infections Program. ; Salt Lake County (Utah). Health Department. Less -
Description:
What is already known about this topic? Most reported SARS-CoV-2 infections in children aged <18 years are asymptomatic or mild. Less is known about severe COVID-19 in children requiring hospitalization.

What is added by this report? Analysis of pediatric COVID-19 hospitalization data from 14 states found that although the cumulative rate of COVID-19–associated hospitalization among children (8.0 per 100,000 population) is low compared with that in adults (164.5), one in three hospitalized children was admitted to an intensive care unit.

What are the implications for public health practice? Children are at risk for severe COVID-19. Public health authorities and clinicians should continue to track pediatric SARS-CoV-2 infections. Reinforcement of prevention efforts is essential in congregate settings that serve children, including childcare centers and schools.

Most reported cases of coronavirus disease 2019 (COVID-19) in children aged <18 years appear to be asymptomatic or mild (1). Less is known about severe COVID-19 illness requiring hospitalization in children. During March 1–July 25, 2020, 576 pediatric COVID-19 cases were reported to the COVID-19–Associated Hospitalization Surveillance Network (COVID-NET), a population-based surveillance system that collects data on laboratory-confirmed COVID-19–associated hospitalizations in 14 states (2,3). Based on these data, the cumulative COVID-19-associated hospitalization rate among children aged <18 years during March 1–July 25, 2020, was 8.0 per 100,000 population, with the highest rate among children aged <2 years (24.8). During March 21–July 25, weekly hospitalization rates steadily increased among children (from 0.1 to 0.4 per 100,000, with a weekly high of 0.7 per 100,000). Overall, Hispanic or Latino (Hispanic) and non-Hispanic black (black) children had higher cumulative rates of COVID-19–associated hospitalizations (16.4 and 10.5 per 100,000, respectively) than did non-Hispanic white (white) children (2.1). Among 208 (36.1%) hospitalized children with complete medical chart reviews, 69 (33.2%) were admitted to an intensive care unit (ICU); 12 of 207 (5.8%) required invasive mechanical ventilation, and one patient died during hospitalization. Although the cumulative rate of pediatric COVID-19–associated hospitalization remains low (8.0 per 100,000 population) compared with that among adults (164.5),* weekly rates increased during the surveillance period, and one in three hospitalized children were admitted to the ICU, similar to the proportion among adults. Continued tracking of SARS-CoV-2 infections among children is important to characterize morbidity and mortality. Reinforcement of prevention efforts is essential in congregate settings that serve children, including childcare centers and schools.

COVID-NET conducts population-based surveillance for laboratory-confirmed COVID-19–associated hospitalizations in 99 counties† in 14 states (California, Connecticut, Colorado, Georgia, Iowa, Maryland, Michigan, Minnesota, New Mexico, New York, Ohio, Oregon, Tennessee, and Utah), representing all 10 U.S. Department of Health and Human Services regions (2,3). Laboratory-confirmed COVID-19–associated hospitalizations among residents in a predefined surveillance catchment area who had a positive SARS-CoV-2 molecular test during hospitalization or up to 14 days before admission are included in surveillance. SARS-CoV-2 tests are ordered at the discretion of the treating health care provider. Trained surveillance officers perform medical chart abstractions for all identified cases. Patients aged <18 years hospitalized with COVID-19 during March 1–July 25, 2020, were included in this analysis. Weekly and cumulative COVID-19–associated hospitalization rates were calculated using the number of catchment area residents hospitalized with COVID-19 as the numerator and the National Center for Health Statistics vintage 2019 bridged-race postcensal population estimates as the denominator.§ Descriptive analyses were conducted using all available data; however, for clinical interventions, treatments, and outcomes, only those hospitalizations with complete medical chart review and a discharge disposition (i.e., discharged alive or died during hospitalization) were included. All analyses were conducted using SAS statistical software (version 9.4; SAS Institute). COVID-NET activities were determined by CDC to be public health surveillance.¶ Participating sites obtained approval for COVID-NET surveillance from their respective state and local Institutional Review Boards, as required.

During March 1–July 25, 576 children hospitalized with COVID-19 were reported to COVID-NET. Infants aged <3 months accounted for 18.8% of all children hospitalized with COVID-19 (Table). The median patient age was 8 years (interquartile range [IQR] = 9 months–15 years), and 292 (50.7%) were males. Among 526 (91.3%) children for whom race and ethnicity information were reported, 241 (45.8%) were Hispanic, 156 (29.7%) were black, 74 (14.1%) were white; 24 (4.6%) were non-Hispanic Asian or Pacific Islander; and four (0.8%) were non-Hispanic American Indian/Alaska Native.

Suggested citation for this article: Yip L, Bixler D, Brooks DE, et al. Serious Adverse Health Events, Including Death, Associated with Ingesting Alcohol-Based Hand Sanitizers Containing Methanol — Arizona and New Mexico, May–June 2020. MMWR Morb Mortal Wkly Rep. ePub: 5 August 2020.

mm6932e3.htm?s_cid=mm6932e3_w

mm6932e3-H.pdf


Subject:
[+]
Betacoronavirus
Child, Hospitalized
Coronavirus Infections
COVID-19
Pandemics
Pneumonia, Viral

Series:
MMWR. Morbidity and mortality weekly report ; v. 69, early release, August 7, 2020
Document Type:
Journal Article
Name as Subject:
COVID-NET ; COVID-NET
COVID-NET ; COVID-NET Less -
Place as Subject:
United States
Collection(s):
Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:
[+]
urn:sha256:ed7c94ea60d4d7476c668e630e64b6480f2f70db0fa2bb06c5fd768a95779325
File Type:

Supporting Files

• mm6932e3.htm?s_cid=mm6932e3_w

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