The Longitudinal Effects of Co-morbid Health Burden on Functional Outcomes for Adults with Moderate-to-Severe Traumatic Brain Injury

Details

• Journal Article:
  J Head Trauma Rehabil
• Personal Author:
  Kumar, Raj G. ; Ketchum, Jessica M. ; Corrigan, John D. ; Hammond, Flora M. ; Sevigny, Mitch ; Dams-O’Connor, Kristen
• Description:
  Objective:
  
  To evaluate the impact of physical, mental, and total health condition burden on functional outcome and life satisfaction up to 10 years after moderate-to-severe traumatic brain injury (TBI).
  
  Setting:
  
  Six TBI Model Systems centers.
  
  Participants:
  
  393 participants in the TBI Model Systems National Database.
  
  Design:
  
  Retrospective cohort study.
  
  Main Measures:
  
  Self-reported physical and mental health conditions at 10-years post-injury. Functional Independence Measure Motor and Cognitive subscales and the Satisfaction with Life Scale measured at 1, 2, 5, and 10 years.
  
  Results:
  
  In 10-year longitudinal individual growth curve models adjusted for covariates and inverse probability weighted to account for selection bias, greater physical and mental health co-morbidity burden were negatively associated with functional cognition and life satisfaction trajectories. Physical, but not mental, co-morbidity burden was negatively associated with functional motor trajectories. Higher total health burden was associated with poorer functional motor and cognitive trajectories and lower life satisfaction.
  
  Conclusions:
  
  This study offers evidence that co-morbidity burden negatively impacts longitudinal functional and life satisfaction outcomes after TBI. The findings suggest better identification and treatment of co-morbidities may benefit life satisfaction, functional outcome, reduced healthcare costs, and decreased re-injury. Specific guidelines are needed for the management of co-morbidities in TBI populations.
  
  
• Subjects:
  Adult Brain Injuries, Traumatic Comorbidity Female Humans Male Mental Health Middle Aged Retrospective Studies Young Adult
• Source:
  J Head Trauma Rehabil. 35(4):E372-E381
• DOI:
  http://dx.doi.org/10.1097/HTR.0000000000000572
• Pubmed ID:
  32108718
• Pubmed Central ID:
  PMC7335323
• Document Type:
  Text ; Journal Article
• Funding:
  90DPTB0009/ACL/ACL HHSUnited States/ ; K01 HD074651/HD/NICHD NIH HHSUnited States/ ; U48 DP000036/DP/NCCDPHP CDC HHSUnited States/
• Genre:
  Journal Article
• Volume:
  35
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:d58a5c9eaba78751073713290264c25cc3610ad1805f564ce22caf32b18f54068ba4a5921884a5d7fbc07d38b37fa2ae295b5226ef95cf1e972d46c9ca226de0
• Download URL:
  https://stacks.cdc.gov/view/cdc/90276/cdc_90276_DS1.pdf
• File Type:
  [PDF - 593.75 KB ]