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The Longitudinal Effects of Co-morbid Health Burden on Functional Outcomes for Adults with Moderate-to-Severe Traumatic Brain Injury
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2020
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Source: J Head Trauma Rehabil. 35(4):E372-E381
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Details:
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Alternative Title:J Head Trauma Rehabil
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Personal Author:
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Description:Objective:
To evaluate the impact of physical, mental, and total health condition burden on functional outcome and life satisfaction up to 10 years after moderate-to-severe traumatic brain injury (TBI).
Setting:
Six TBI Model Systems centers.
Participants:
393 participants in the TBI Model Systems National Database.
Design:
Retrospective cohort study.
Main Measures:
Self-reported physical and mental health conditions at 10-years post-injury. Functional Independence Measure Motor and Cognitive subscales and the Satisfaction with Life Scale measured at 1, 2, 5, and 10 years.
Results:
In 10-year longitudinal individual growth curve models adjusted for covariates and inverse probability weighted to account for selection bias, greater physical and mental health co-morbidity burden were negatively associated with functional cognition and life satisfaction trajectories. Physical, but not mental, co-morbidity burden was negatively associated with functional motor trajectories. Higher total health burden was associated with poorer functional motor and cognitive trajectories and lower life satisfaction.
Conclusions:
This study offers evidence that co-morbidity burden negatively impacts longitudinal functional and life satisfaction outcomes after TBI. The findings suggest better identification and treatment of co-morbidities may benefit life satisfaction, functional outcome, reduced healthcare costs, and decreased re-injury. Specific guidelines are needed for the management of co-morbidities in TBI populations.
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Pubmed ID:32108718
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Pubmed Central ID:PMC7335323
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