Prevalence of selected birth defects by maternal nativity status, United States, 1999–2007

Details

• Alternative Title:
  Birth Defects Res
• Personal Author:
  Kirby, Russell S. ; Mai, Cara T. ; Wingate, Martha S. ; Janevic, Teresa ; Copeland, Glenn E. ; Flood, Timothy J. ; Isenburg, Jennifer ; Canfield, Mark A.
• Corporate Authors:
  for the National Birth Defects Prevention Network
• Description:
  Objectives:
  
  We investigated differences in prevalence of major birth defects by maternal nativity within racial/ethnic groups for 27 major birth defects.
  
  Methods:
  
  Data from 11 population-based birth defects surveillance systems in the United States including almost 13 million live births (approximately a third of U.S. births) during 1999–2007 were pooled. We calculated prevalence estimates for each birth defect for five racial/ethnic groups. Using Poisson regression, crude and adjusted prevalence ratios (aPRs) were also calculated using births to US-born mothers as the referent group in each racial/ethnic group.
  
  Results:
  
  Approximately 20% of case mothers and 26% of all mothers were foreign-born. Elevated aPRs for infants with foreign-born mothers were found for spina bifida and trisomy 13, 18, and 21, while lower prevalence patterns were found for pyloric stenosis, gastroschisis, and hypospadias.
  
  Conclusions:
  
  This study demonstrates that birth defects prevalence varies by nativity within race/ethnic groups, with elevated prevalence ratios for some specific conditions and lower prevalence for others. More detailed analyses focusing on a broader range of maternal behaviors and characteristics are required to fully understand the implications of our findings.
  
  
• Subjects:
  Congenital Abnormalities Emigrants And Immigrants Ethnicity Female Humans Infant Infant, Newborn Male Mothers Population Surveillance Prevalence Racial Groups United States

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• Keywords:
  Birth Defects Epidemiology Nativity Population Health Race/Ethnicity
• Source:
  Birth Defects Res. 111(11):630-639
• Pubmed ID:
  30920179
• Pubmed Central ID:
  PMC7222225
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  111
• Issue:
  11
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:b1e77c38bea4535b20683959c5c5a286b865f55059a1c08da98ef35b99168140
• Download URL:
  https://stacks.cdc.gov/view/cdc/88016/cdc_88016_DS1.pdf
• File Type:
  [PDF - 401.76 KB ]