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Prevalence of selected birth defects by maternal nativity status, United States, 1999–2007
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7 01 2019
Source: Birth Defects Res. 111(11):630-639 -
Alternative Title:Birth Defects Res
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Description:Objectives:
We investigated differences in prevalence of major birth defects by maternal nativity within racial/ethnic groups for 27 major birth defects.
Methods:
Data from 11 population-based birth defects surveillance systems in the United States including almost 13 million live births (approximately a third of U.S. births) during 1999–2007 were pooled. We calculated prevalence estimates for each birth defect for five racial/ethnic groups. Using Poisson regression, crude and adjusted prevalence ratios (aPRs) were also calculated using births to US-born mothers as the referent group in each racial/ethnic group.
Results:
Approximately 20% of case mothers and 26% of all mothers were foreign-born. Elevated aPRs for infants with foreign-born mothers were found for spina bifida and trisomy 13, 18, and 21, while lower prevalence patterns were found for pyloric stenosis, gastroschisis, and hypospadias.
Conclusions:
This study demonstrates that birth defects prevalence varies by nativity within race/ethnic groups, with elevated prevalence ratios for some specific conditions and lower prevalence for others. More detailed analyses focusing on a broader range of maternal behaviors and characteristics are required to fully understand the implications of our findings.
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Pubmed ID:30920179
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Pubmed Central ID:PMC7222225
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