Methicillin-Resistant Staphylococcus aureus Bloodstream Infections and Injection Drug Use, Tennessee, USA, 2015–2017

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Parikh, Meghana P. ; Octaria, Rany ; Kainer, Marion A.
• Description:
  Recently, Tennessee, USA, has seen an increase in the use of commonly injected drugs, such as heroin and fentanyl. Injection drug use (IDU) practices can lead to life-threatening methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections (BSIs) and other serious diseases. We matched MRSA BSIs identified through the National Healthcare Safety Network to the Tennessee Hospital Discharge Data System to characterize the prevalence, demographics, and clinical characteristics associated with IDU in this disease population. Of the 7,646 MRSA BSIs identified during 2015-2017, we found that 1,839 (24.1%) were IDU-related. IDU-related BSIs increased by 118.9%; the greatest rise occurred among emergency department-onset infections (197.4%). IDU was more often associated with white, female, 18-49-year-old, and uninsured persons (p<0.001). We found >1 additional IDU-related diagnoses in 84.2% of IDU-related BSIs. Targeted harm reduction strategies for persons at high risk of IDU are necessary to reduce MRSA BSIs in acute care settings.
• Subjects:
  Antimicrobial Resistance Bacteria Endocarditis Hepatitis C Illicit Drugs Methicillin-resistant Staphylococcus Aureus Methicillin-Resistant Staphylococcus Aureus Bloodstream Infections And Injection Drug Use, Tennessee, USA, 2015–2017 MRSA Research
• Source:
  Emerg Infect Dis. 26(3):446-453
• Pubmed ID:
  32091385
• Pubmed Central ID:
  PMC7045815
• Document Type:
  Journal Article
• Place as Subject:
  Tennessee
• Location:
  North America
• Volume:
  26
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:a4151aa7952c0ee529f3155153ff3a000410881d053a98f19135b7a017ec36b2
• Download URL:
  https://stacks.cdc.gov/view/cdc/85692/cdc_85692_DS1.pdf
• File Type:
  [PDF - 991.24 KB ]