Details:

Alternative Title:
Int J Syst Evol Microbiol
Personal Author:
Dietrich, Elizabeth A. ; Kingry, Luke C. ; Kugeler, Kiersten J. ; Levy, Craig ; Yaglom, Hayley ; ... More +
Dietrich, Elizabeth A. ; Kingry, Luke C. ; Kugeler, Kiersten J. ; Levy, Craig ; Yaglom, Hayley ; Young, John W. ; Mead, Paul S. ; Petersen, Jeannine M. Less -
Description:
Two isolates of a Gram-negative, non-spore-forming coccobacillus cultured from the blood and cerebrospinal fluid of immunocompromised patients in the United States were described previously. Biochemical and phylogenetic analyses revealed that they belong to a novel species within the | genus. Here we describe a third isolate of this species, recovered from blood of a febrile patient with renal failure, and formally name the | species. Whole genome comparisons indicated the three isolates display greater than 99.9 % average nucleotide identity (ANI) to each other and are most closely related to the tick endosymbiont |, with only 88.6-88.8 % ANI to the type strain of |. Based on biochemical, metabolic and genomic comparisons, we propose that these three isolates should be recognized as | sp. nov, with the type strain of the species, PA05-1188|, available through the Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSM 107100) and the American Type Culture Collection (ATCC BAA-2974).
Subject:
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Bacterial Typing Techniques
Base Composition
Blood
Cerebrospinal Fluid
DNA, Bacterial
Francisella
Genes, Bacterial
Humans
Phylogeny
RNA, Ribosomal, 16S
Sequence Analysis, DNA

Source:
Int J Syst Evol Microbiol. 70(2):1145-1151
Pubmed ID:
31860434
Pubmed Central ID:
PMC7056488
Document Type:
Journal Article
Funding:
CC999999/ImCDC/Intramural CDC HHS/United States
Place as Subject:
United States
Collection(s):
CDC Public Access
Main Document Checksum:
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urn:sha256:3c57276eb34b8a9c246d2f73c0ba43379b5615df7ee3f9597c24d84914002535
File Type:

Supporting Files

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