Details:

Alternative Title:
Support Care Cancer
Personal Author:
Fauer, Alex J.; Davis, Matthew A.; Choi, Sung Won; Wallner, Lauren P.; Friese, Christopher R.;
Fauer, Alex J.; Davis, Matthew A.; Choi, Sung Won; Wallner, Lauren P.; Friese, Christopher R.; Less -
Description:
Background Gabapentinoid use for cancer-pain control may be problematic, given unclear mechanisms of action and increased concerns for physical dependence. The purpose of this report is to examine trends of gabapentinoid use among US adults with cancer from 2005–2015. Methods We conducted a serial, cross-sectional study using data from the Medical Expenditure Panel Survey (MEPS). We performed multiple logistic regression to examine the annual percentages of gabapentinoid users, which were adjusted for age, sex, and US region of residence. Results The amount of gabapentinoid prescriptions filled in 2015 was also estimated. The adjusted percentage of gabapentinoid users in 2015 was 5.60% (3.79%, 7.41%), 2.39 times greater than the percentage in 2005 (p < .001). By 2015, the number of gabapentinoid prescriptions had grown to approximately 3.52 million (2.40 million, 4.65 million). Conclusion We observed greater than a two-fold increase in the trend of gabapentinoid medication use among US adults with cancer. Investigations on the long-term efficacy of gabapentinoids for complex pain syndromes, and mitigation of risks, is essential to guide informed clinical management and keep patients safe.
Subject:
[+]
Adolescent
Adult
Aged
Aged, 80 And Over
Analgesics
Cancer Pain
Chronic Pain
Cross-Sectional Studies
Female
Gabapentin
Humans
Male
Middle Aged
Neoplasms
Pain Management
Palliative Care
Practice Patterns, Physicians'
Substance-Related Disorders
Surveys And Questionnaires
Young Adult

Source:
Support Care Cancer. 28(1):5-8;
Pubmed ID:
31650294
Pubmed Central ID:
PMC6884691
Document Type:
Journal Article;
Funding:
P30 CA046592/CA/NCI NIH HHS/United States; T42 OH008455/OH/NIOSH CDC HHS/United States; 133507-DSCN-19-048-01-SCN/American Cancer Society/; P30CA046592/CA/NCI NIH HHS/United States;
P30 CA046592/CA/NCI NIH HHS/United States; T42 OH008455/OH/NIOSH CDC HHS/United States; 133507-DSCN-19-048-01-SCN/American Cancer Society/; P30CA046592/CA/NCI NIH HHS/United States; Less -
Place as Subject:
United States;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:faa89d500546f5690182a11c8ac55e6a200718ebf580538fec2285219dc5406c
File Type:

Supporting Files

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