Use of Gabapentinoid Medications Among US adults with Cancer, 2005-2015

Fauer, Alex J.; Davis, Matthew A.; Choi, Sung Won; Wallner, Lauren P.; Friese, Christopher R.

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Use of Gabapentinoid Medications Among US adults with Cancer, 2005-2015

Published Date:

October 25 2019

Source:

Support Care Cancer. 28(1):5-8

Language:

English

[PDF-74.44 KB]

Details:

Alternative Title:

Support Care Cancer

Personal Author:

Fauer, Alex J. ; Davis, Matthew A. ; Choi, Sung Won ; Wallner, Lauren P. ; Friese, Christopher R. ;

Description:

Background Gabapentinoid use for cancer-pain control may be problematic, given unclear mechanisms of action and increased concerns for physical dependence. The purpose of this report is to examine trends of gabapentinoid use among US adults with cancer from 2005–2015. Methods We conducted a serial, cross-sectional study using data from the Medical Expenditure Panel Survey (MEPS). We performed multiple logistic regression to examine the annual percentages of gabapentinoid users, which were adjusted for age, sex, and US region of residence. Results The amount of gabapentinoid prescriptions filled in 2015 was also estimated. The adjusted percentage of gabapentinoid users in 2015 was 5.60% (3.79%, 7.41%), 2.39 times greater than the percentage in 2005 (p < .001). By 2015, the number of gabapentinoid prescriptions had grown to approximately 3.52 million (2.40 million, 4.65 million). Conclusion We observed greater than a two-fold increase in the trend of gabapentinoid medication use among US adults with cancer. Investigations on the long-term efficacy of gabapentinoids for complex pain syndromes, and mitigation of risks, is essential to guide informed clinical management and keep patients safe.

Subject:

[+]

Pubmed ID:

31650294

Pubmed Central ID:

PMC6884691

Document Type:

Journal Article

Funding:

P30 CA046592/CA/NCI NIH HHS/United States ; T42 OH008455/OH/NIOSH CDC HHS/United States ; 133507-DSCN-19-048-01-SCN/American Cancer Society/ ; P30CA046592/CA/NCI NIH HHS/United States ;

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CDC Public Access

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	nihms-1541520.nxml	text/xml
	NIHMS1541520-supplement-520_2019_5100_MOESM1_ESM.docx	application/vnd.openxmlformats-officedocument.wordprocessingml.document

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Use of Gabapentinoid Medications Among US adults with Cancer, 2005-2015

Use of Gabapentinoid Medications Among US adults with Cancer, 2005-2015

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