Details:

Alternative Title:
Sex Transm Dis
Personal Author:
Abrams, A. Jeanine ; Kirkcaldy, Robert D. ; Pettus, Kevin ; Fox, Jan L. ; Kubin, Grace ; ... More +
Abrams, A. Jeanine ; Kirkcaldy, Robert D. ; Pettus, Kevin ; Fox, Jan L. ; Kubin, Grace ; Trees, David L. ; Less -
Description:
We report a case of Neisseria gonorrhoeae with a non-mosaic penA allele that exhibited decreased susceptibility to extended-spectrum cephalosporins, including a ceftriaxone minimum inhibitory concentration of 0.5 μg/mL. An analysis of resistance determinants suggested that the observed phenotype might have resulted from the combined effects of mutations in multiple genes.
Subject:
[+]
Adult
Alleles
Anti-Bacterial Agents
Article
Carrier Proteins
Ceftriaxone
Drug Resistance, Bacterial
Gonorrhea
Humans
Male
Microbial Sensitivity Tests
Mutation
Neisseria Gonorrhoeae
Phenotype
Serine-Type D-Ala-D-Ala Carboxypeptidase
Urethra
Urethritis

Source:
Sex Transm Dis. 44(8):492-494 ;
Pubmed ID:
28703729
Pubmed Central ID:
PMC6932624
Document Type:
Journal Article ;
Funding:
CC999999/ImCDC/Intramural CDC HHS/United States ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:ee6b69f311a459a7f87b656b23357580ec6a6a6b8446d5a0c7caf93e42749308
File Type:

Supporting Files

• nihms-1062132.nxml

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