Association between chlorhexidine gluconate concentrations and resistant bacterial bioburden on skin

Details

• Alternative Title:
  Infect Control Hosp Epidemiol
• Personal Author:
  Nadimpalli, Gita ; O’Hara, Lyndsay M. ; Leekha, Surbhi ; Calfee, David P. ; Miller, Loren G. ; Pineles, Lisa ; Blanco, Natalia ; Johnson, J. Kristie ; Harris, Anthony D.
• Description:
  We studied the association between chlorhexidine gluconate (CHG) concentration on skin and resistant bacterial bioburden. CHG was almost always detected on the skin, and detection of methicillin-resistant Staphylococcus aureus, carbapenem-resistant Enterobacteriaceae, and vancomycin-resistant Enterococcus on skin sites was infrequent. However, we found no correlation between CHG concentration and bacterial bioburden.
• Subjects:
  Anti-Infective Agents, Local Article Chlorhexidine Dose-Response Relationship, Drug Drug Resistance, Bacterial Humans Skin
• Source:
  Infect Control Hosp Epidemiol. 40(12):1430-1432
• Pubmed ID:
  31601280
• Pubmed Central ID:
  PMC6897301
• Document Type:
  Journal Article
• Funding:
  R01 AI121146/AI/NIAID NIH HHS/United States ; U54 CK000450/CK/NCEZID CDC HHS/United States ; U54CK000450/ACL/ACL HHS/United States
• Volume:
  40
• Issue:
  12
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:cfab01688271d2aa535f776cc230ddd9b32d3855f80c7eb143a8b8cf45d776f0
• Download URL:
  https://stacks.cdc.gov/view/cdc/83233/cdc_83233_DS1.pdf
• File Type:
  [PDF - 300.08 KB ]