Details:

Alternative Title:
Open J Obstet Gynecol
Personal Author:
Pérez-Padilla, Janice ; Paz-Bailey, Gabriela ; Meaney-Delman, Dana ; Doyle, Kate ; Gary, Joy ; ... More +
Pérez-Padilla, Janice ; Paz-Bailey, Gabriela ; Meaney-Delman, Dana ; Doyle, Kate ; Gary, Joy ; Rodriguez, Dania M. ; Bhatnagar, Julu ; Pérez-Rodriguez, Nicole M. ; Montalvo, Sara ; Alvarado, Luisa ; Sharp, Tyler M. ; Less -
Description:
Background: Infection with Zika virus (ZIKV) during pregnancy is known to cause birth defects and could also be linked to pregnancy loss. Case: A pregnant woman in Puerto Rico contracted ZIKV at 16 weeks gestation. ZIKV RNA persisted in serum from her initial test at 16 weeks through 24 weeks gestation, when fetal demise occurred, and was detected in placental tissue. Conclusion: Prolonged detection of ZIKV RNA in maternal serum was associated with ZIKV RNA detection in the placenta of a patient who experienced fetal demise. While detection of placenta ZIKV RNA does not establish that ZIKV conclusively caused the demise, these findings support emerging evidence that the placenta may serve as a reservoir for ZIKV, which may be associated with prolonged detection of ZIKV RNA in serum.
Subject:
[+]
Article
Pregnancy Outcomes
Zika
ZIKV Persistence

Source:
Open J Obstet Gynecol. 9(5):698-706 ;
Pubmed ID:
31799062
Pubmed Central ID:
PMC6889876
Document Type:
Journal Article ;
Funding:
CC999999/ImCDC/Intramural CDC HHS/United States ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:7e1172ca0488d8523a47a525e05a389f95aca72965f085b24e19d74f706a52ff
File Type:

Supporting Files

• 	nihms-1059320-f0001.gif	gif
  	nihms-1059320-f0001.jpg	jpeg
  	nihms-1059320.nxml	xml

More +