Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Hu, Yan-Yan ; Cao, Jun-Min ; Yang, Qing ; Chen, Shi ; Lv, Huo-Yang ; Zhou, Hong-Wei ; Wu, Zuowei ; Zhang, Rong
• Description:
  Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a public health concern worldwide, but comprehensive analysis of risk factors for CRPA remains limited in China. We conducted a retrospective observational study of carbapenem resistance in 71,880 P. aeruginosa isolates collected in Zhejiang Province during 2015-2017. We analyzed risk factors for CRPA, including the type of clinical specimen; the year, season, and region in which it was collected; patient information, including age, whether they were an outpatient or inpatient, and whether inpatients were in the intensive care unit or general ward; and the level of hospital submitting isolates. We found CRPA was more prevalent among isolates from patients >60 years of age and in inpatients, especially in intensive care units. In addition, specimen types and seasons in which they were collected were associated with higher rates of CRPA. Our findings can help hospitals reduce the spread of P. aeruginosa and optimize antimicrobial drug use.
• Subjects:
  Adult Age Factors Beta-Lactam Resistance Carbapenems Child Child, Preschool Cross Infection Humans Infant Infant, Newborn Microbial Sensitivity Tests Middle Aged Olescent Pseudomonas Aeruginosa Pseudomonas Infections Retrospective Studies Risk Factors Young Adult

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• Source:
  Emerg Infect Dis. 25(10):1861-1867
• Pubmed ID:
  31538558
• Pubmed Central ID:
  PMC6759267
• Document Type:
  Journal Article
• Place as Subject:
  China
• Volume:
  25
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:e19560996dc4cec9919d1c21e17a2e495ead42d1de2782e8c2341002532fd683
• Download URL:
  https://stacks.cdc.gov/view/cdc/82942/cdc_82942_DS1.pdf
• File Type:
  [PDF - 1.41 MB ]