Details:

Alternative Title:
Sex Transm Dis
Personal Author:
Rönn, Minttu M. ; Wolf, Emory E. ; Chesson, Harrell ; Menzies, Nicolas A. ; Galer, Kara ; ... More +
Rönn, Minttu M. ; Wolf, Emory E. ; Chesson, Harrell ; Menzies, Nicolas A. ; Galer, Kara ; Gorwitz, Rachel ; Gift, Thomas ; Hsu, Katherine ; Salomon, Joshua A. Less -
Description:
Background:

Mathematical models of chlamydia transmission can help inform disease control policy decisions when direct empirical evaluation of alternatives is impractical. We reviewed published chlamydia models to understand the range of approaches used for policy analyses and how the studies have responded to developments in the field.

Methods:

We performed a literature review by searching Medline and Google Scholar (up to October 2015) to identify publications describing dynamic chlamydia transmission models used to address public health policy questions. We extracted information on modeling methodology, interventions, and key findings.

Results:

We identified 47 publications (including two model comparison studies), which reported collectively on 29 distinct mathematical models. Nine models were individual-based, and 20 were deterministic compartmental models. The earliest studies evaluated the benefits of national-level screening programs and predicted potentially large benefits from increased screening. Subsequent trials and further modeling analyses suggested the impact might have been overestimated. Partner notification has been increasingly evaluated in mathematical modeling, whereas behavioral interventions have received relatively limited attention.

Conclusions:

Our review provides an overview of chlamydia transmission models and gives a perspective on how mathematical modeling has responded to increasing empirical evidence and addressed policy questions related to prevention of chlamydia infection and sequelae.


Subjects:
[+]
Chlamydia Chlamydia Infections Contact Tracing Health Policy Humans Models, Theoretical
Source:
Sex Transm Dis. 44(5):278-283
Pubmed ID:
28407643
Pubmed Central ID:
PMC6727649
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHSUnited States/
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:726cd62bfea2252e1300de04d417102cbbf1ed572d839c2144bf5e79d990c2b2
Download URL:
https://stacks.cdc.gov/view/cdc/81250/cdc_81250_DS1.pdf
File Type:

Supporting Files

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  	NIHMS1048562-supplement-Supplement_1.pdf	pdf
  	NIHMS1048562-supplement-Supplement_2.pdf	pdf
  	NIHMS1048562-supplement-Supplement_3.pdf	pdf

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