Use and interpretation of hemoglobin concentrations for assessing anemia status in individuals and populations: results from a WHO technical meeting

Details

• Alternative Title:
  Ann N Y Acad Sci
• Personal Author:
  Garcia-Casal, Maria Nieves ; Pasricha, Sant-Rayn ; Sharma, Andrea J. ; Peña-Rosas, Juan Pablo
• Description:
  Anemia is an important public health problem that negatively affects health of individuals and economic potential of populations. An accurate case definition is critical for understanding burden and epidemiology of anemia, for planning public health interventions, and for clinical investigation and treatment of patients. The current threshold hemoglobin concentrations for diagnosis of anemia were proposed in 1968 and based on studies predominantly of Caucasian adult populations in Europe and North America. The World Health Organization is undertaking a project to review global guidelines for anemia. We describe the process of obtaining input from technical experts, researchers, blood bank experts, policy makers, and program implementers to identify key information or knowledge gaps for anemia diagnosis. From this scoping exercise, six priority areas were identified on diverse topics related to the use and interpretation of hemoglobin concentrations to diagnose anemia in individuals and populations. A call for authors was conducted to produce background, review, and research papers across priority topics. This paper summarizes the first technical meeting, which included commissioned papers as well as case studies, describes key data gaps identified, and describes the next steps in the guideline development process to assess available evidence and define knowledge gaps to improve anemia characterization.
• Subjects:
  Anemia Global Health Hemoglobins Humans
• Keywords:
  Anemia Clinical Significance Hemoglobin Public Health Technical Meeting Thresholds
• Source:
  Ann N Y Acad Sci. 1450(1):5-14
• Pubmed ID:
  31006883
• Pubmed Central ID:
  PMC6703163
• Document Type:
  Journal Article
• Funding:
  Evidence and Programme Guidance Unit, Department of Nutrition for Health and DevelopmentInternational/ ; United States Agency for International DevelopmentInternational/ ; Bill & Melinda Gates Foundation, USAInternational/ ; International Micronutrient Malnutrition Prevention and Control Programme (IMMPaCt)International/ ; Evidence and Programme Guidance Unit, Department of Nutrition for Health and Development of the World Health Organization (WHO), Geneva, SwitzerlandInternational/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/ ; International Micronutrient Malnutrition Prevention and Control Programme (IMMPaCt) at the Centers for Disease Control and Prevention (CDC), USAInternational/ ; Bill and Melinda Gates FoundationInternational/ ; United States Agency for International Development (USAID), USAInternational/ ; 001/WHO_/World Health OrganizationInternational/ ; CC/CDC HHSUnited States/
• Name as Subject:
  World Health Organization
• Volume:
  1450
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:e2dac8a55cba78cd69c65fbbd3030ca4032bdaef197ee6b8686d4d3bdebe9db7
• Download URL:
  https://stacks.cdc.gov/view/cdc/80865/cdc_80865_DS1.pdf
• File Type:
  [PDF - 69.55 KB ]