Effects of Physical Activity in Knee and Hip Osteoarthritis: A Systematic Umbrella Review

Details

• Alternative Title:
  Med Sci Sports Exerc
• Personal Author:
  Kraus, Virginia B ; Sprow, Kyle ; Powell, Kenneth E. ; Buchner, David ; Bloodgood, Bonny ; Piercy, Katrina ; George, Stephanie M. ; Kraus, William E
• Description:
  Introduction.
  
  We conducted a systematic umbrella review to evaluate the literature relating to effects of physical activity on pain, physical function, health-related quality of life (HRQoL), co-morbid conditions and osteoarthritis (OA) structural disease progression in individuals with lower extremity OA.
  
  Methods.
  
  Our primary search encompassed 2011 – 2/2018 for existing systematic reviews (SRs), meta-analyses (MAs) and pooled analyses dealing with physical activity including exercise (not mixed with any other intervention and compared to a no-activity control group). A supplementary search encompassed 2006-2/2018 for original research related to physical activity (including exercise) and lower limb OA progression. Study characteristics were abstracted and risk of bias was assessed.
  
  Results.
  
  Physical activity decreased pain and improved physical function (strong evidence) and improved HRQoL (moderate evidence) among people with hip or knee OA relative to less active adults with OA. There was no evidence to suggest accelerated OA progression for physical activity below 10,000 steps per day. Both physical activity equivalent to the 2008 Physical Activity Guidelines for Americans (150 minutes/week of moderate-intensity exercise in bouts ≥10 minutes) and lower levels of physical activity (at least 45 total minutes/week of moderate-intensity) were associated with improved or sustained high function. No SRs/MAs addressing co-morbid conditions in OA were found. Measurable benefits of physical activity appeared to persist for periods of up to 6 months following cessation of a defined program.
  
  Conclusions.
  
  People with lower extremity OA should be encouraged to engage in achievable amounts of physical activity, of even modest intensities. They can choose to accrue minutes of physical activity throughout the entire day, irrespective of bout duration, and be confident in gaining some health and arthritis-related benefits.
  
  
• Subjects:
  Article Function Hip Knee Pain Progression Quality Of Life
• Source:
  Med Sci Sports Exerc. 51(6):1324-1339
• Pubmed ID:
  31095089
• Pubmed Central ID:
  PMC6527143
• Document Type:
  Journal Article
• Funding:
  Z99 OD999999/CD/ODCDC CDC HHS/United States
• Volume:
  51
• Issue:
  6
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:f67698acc2e8cb41c2dd58d756d8982c02c8ff5dececfd2d47f2867c1756db74
• Download URL:
  https://stacks.cdc.gov/view/cdc/80658/cdc_80658_DS1.pdf
• File Type:
  [PDF - 1.71 MB ]