Defying birth defects through diet?

Details

• Alternative Title:
  Genome Med
• Personal Author:
  Crider, Krista S. ; Bailey, Lynn B.
• Description:
  The risk of certain birth defects can be modified by maternal diet. A high-fat maternal mouse diet has recently been reported to substantially increase the penetrance of birth defects known to be associated with a deficiency of transcription factor Cited2 as well as induce cleft palate. These effects were associated with a more than twofold reduction in embryonic expression of Pitx2c. This investigation suggests the need to further explore this provocative gene-diet interaction in human studies.
• Subjects:
  Commentary
• Source:
  Genome Med. 2011; 3(2):9.
• Document Type:
  Journal Article
• Volume:
  3
• Issue:
  2
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:9864b49ae71ba0d988c9027d605de265bca86ee5b54434a5e4b86749f25f6fc2
• Download URL:
  https://stacks.cdc.gov/view/cdc/8065/cdc_8065_DS1.pdf
• File Type:
  [PDF - 235.42 KB ]