Identification and Selection of Cases and Controls in the Pneumonia Etiology Research for Child Health Project

Details

• Alternative Title:
  Clin Infect Dis
• Personal Author:
  Deloria-Knoll, Maria ; Feikin, Daniel R. ; Scott, J. Anthony G. ; O’Brien, Katherine L. ; DeLuca, Andrea N. ; Driscoll, Amanda J. ; Levine, Orin S.
• Corporate Authors:
  Pneumonia Methods Working Group
• Description:
  Methods for the identification and selection of patients (cases) with severe or very severe pneumonia and controls for the Pneumonia Etiology Research for Child Health (PERCH) project were needed. Issues considered include eligibility criteria and sampling strategies, whether to enroll hospital or community controls, whether to exclude controls with upper respiratory tract infection (URTI) or nonsevere pneumonia, and matching criteria, among others. PERCH ultimately decided to enroll community controls and an additional human immunodeficiency virus (HIV)-infected control group at high HIV-prevalence sites matched on age and enrollment date of cases; controls with symptoms of URTI or nonsevere pneumonia will not be excluded. Systematic sampling of cases (when necessary) and random sampling of controls will be implemented. For each issue, we present the options that were considered, the advantages and disadvantages of each, the rationale for the methods selected for PERCH, and remaining implications and limitations.
• Subjects:
  Bias (Epidemiology) Case-Control Studies Child, Hospitalized Child, Preschool Child Welfare Epidemiologic Research Design HIV Infections Humans Infant Patient Selection Pneumonia Prevalence Respiratory Tract Infections

  More +
• Source:
  Clin Infect Dis. 2012; 54(Suppl 2):S117-S123.
• Document Type:
  Journal Article
• Volume:
  54
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:f0386900bfeab17aedf3b8a51560dae2f0e2e05f1ff763e8c19c5f57d23d3d7d
• Download URL:
  https://stacks.cdc.gov/view/cdc/8045/cdc_8045_DS1.pdf
• File Type:
  [PDF - 624.61 KB ]