The Pneumonia Etiology Research for Child Health Project: A 21st Century Childhood Pneumonia Etiology Study

Details

• Alternative Title:
  Clin Infect Dis
• Personal Author:
  Levine, Orin S. ; O’Brien, Katherine L. ; Deloria-Knoll, Maria ; Murdoch, David R. ; Feikin, Daniel R. ; DeLuca, Andrea N. ; Driscoll, Amanda J. ; Baggett, Henry C. ; Brooks, W. Abdullah ; Howie, Stephen R. C. ; Kotloff, Karen L. ; Madhi, Shabir A. ; Maloney, Susan A. ; Sow, Samba ; Thea, Donald M. ; Scott, J. Anthony
• Description:
  The Pneumonia Etiology Research for Child Health (PERCH) project is a 7-country, standardized, comprehensive evaluation of the etiologic agents causing severe pneumonia in children from developing countries. During previous etiology studies, between one-quarter and one-third of patients failed to yield an obvious etiology; PERCH will employ and evaluate previously unavailable innovative, more sensitive diagnostic techniques. Innovative and rigorous epidemiologic and analytic methods will be used to establish the causal association between presence of potential pathogens and pneumonia. By strategic selection of study sites that are broadly representative of regions with the greatest burden of childhood pneumonia, PERCH aims to provide data that reflect the epidemiologic situation in developing countries in 2015, using pneumococcal and Haemophilus influenzae type b vaccines. PERCH will also address differences in host, environmental, and/or geographic factors that might determine pneumonia etiology and, by preserving specimens, will generate a resource for future research and pathogen discovery.
• Subjects:
  Child, Hospitalized Child, Preschool Child Welfare Data Collection Developing Countries Epidemiologic Research Design Geography Haemophilus Infections Haemophilus Influenzae Type B Humans Infant Pneumococcal Infections Pneumonia Risk Factors Streptococcus Pneumoniae

  More +
• Source:
  Clin Infect Dis. 2012; 54(Suppl 2):S93-S101.
• Document Type:
  Journal Article
• Volume:
  54
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:600ea34d09f8df196b8bd1435c47b0694d0754858bf4f02e0cd62df150fae554
• Download URL:
  https://stacks.cdc.gov/view/cdc/8043/cdc_8043_DS1.pdf
• File Type:
  [PDF - 317.27 KB ]