Cigarette ignition propensity, smoking behavior, and toxicant exposure: A natural experiment in Canada

Details

• Alternative Title:
  Tob Induc Dis
• Personal Author:
  June, Kristie M ; Hammond, David ; Sjödin, Andreas ; Li, Zheng ; Romanoff, Lovisa ; O'Connor, Richard J
• Description:
  Background
  
  This study used a 'pre-post' research design to measure the impact of the Canadian reduced ignition propensity law on cigarette toxicity and smoking behavior among Canadian smokers.
  
  Method
  
  The study was conducted in Ontario, Canada over a ten-month period in 2005-2006, consisting of 4 laboratory visits (baseline N = 61, final N = 42). At Visit 1, questionnaire data and biospecimens were collected. During the following 24 hours, participants smoked 5 cigarettes ad libitum through a topography recording device and collected their cigarette butts. Visit 2 consisted of a questionnaire and smoking one cigarette to measure laboratory topography values. After ten months, these procedures were repeated.
  
  Results
  
  Generalized estimating equations, with law status (pre and post) as a fixed within-subject factor, were used to determine changes in behavior and biomarker exposure. Overall, there were no significant differences in smoking topography, breath carbon monoxide, and saliva cotinine pre-post law (p>0.1). However, analyses revealed a significant increase in the summed concentrations of hydroxyfluorene metabolites (N = 3),, and 1-hydroxypyrene in urine, with at notable increase in hydroxyphenanthrene metabolites (N = 3) (pΣhydroxyfluorene = 0.013, 22% increase; p1-hydroxypyrene = 0.018, 24% increase; pΣhydroxyphenanthrene = 0.061, 17% increase).
  
  Conclusion
  
  While the results suggest no change in topography variables, data showed increases in exposure to three PAH biomarkers following reduced ignition propensity implementation in Canada. These findings suggest that human studies should be considered to evaluate policy impacts.
  
  
• Subjects:
  Polycyclic Aromatic Hydrocarbons (PAH) Reduced Ignition Propensity (RIP) Cigarettes Research Smoking Topography
• Source:
  Tob Induc Dis. 2011; 9(1):13.
• Document Type:
  Journal Article
• Volume:
  9
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:35185448b243525540fc8195d6d26dff3166623ad2ea4938e9c3544b1c207819
• Download URL:
  https://stacks.cdc.gov/view/cdc/8011/cdc_8011_DS1.pdf
• File Type:
  [PDF - 263.97 KB ]