Couples HIV testing and immediate antiretroviral therapy for serodiscordant HIV-positive partners: Translating evidence into programme in Vietnam

Details

• Alternative Title:
  Int J STD AIDS
• Personal Author:
  Bui, Duong D ; Do, Nhan T ; Pham, Linh TT ; Nadol, Patrick ; Nguyen, Van TT ; Dao, Vinh Q ; Nguyen, Long H ; Duong, Tuan K ; Lai, Anh K ; Hoang, Chian X ; Nguyen, Anh H ; Suthar, Amitabh ; Tong, An L ; Do, Hoa M ; Mesquita, Fabio ; Lo, Ying-Ru ; Lyss, Sheryl ; Nguyen, Long T ; Kato, Masaya
• Description:
  Injection drug use and heterosexual transmission from male key populations to their female partners have been the dominant modes of HIV transmission in Vietnam. A demonstration project was conducted to offer immediate antiretroviral therapy (ART) (regardless of CD4 cell count) to HIV-seropositive partners in serodiscordant couples. During March–December 2013, couples HIV testing and counselling (HTC) and immediate ART were offered in two drug use-affected provinces. Of 256 couples receiving couples HTC, 146 (57%) were serodiscordant; 134 (92%) seropositive partners initiated ART irrespective of CD4 cell count. Of these, 86% were male; 57% reported ever using illicit drugs; median CD4 cell count before ART initiation was 374 cells/mm|. Consistent condom use was reported by 58, 70 and 71% among HIV-positive partners at months 0, 3 and 12. At 12 months after ART initiation, 119 (89%) HIV-positive partners were retained in care; 96 (95% of those tested) achieved viral suppression (<1000 copies/ml). Uptake of immediate ART and viral suppression among those initiating ART were high, paving the way for ART regardless of CD4 cell count as national policy in Vietnam.
• Keywords:
  Adult Anti-HIV Agents Antiretroviral Therapy Antiretroviral Therapy, Highly Active Asia Feasibility Studies Female Heterosexuality HIV HIV Infections HIV Seropositivity Humans Male Middle Aged Prevention Sexual Partners Vietnam

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• Source:
  Int J STD AIDS. 30(8):739-747
• Pubmed ID:
  31046612
• Pubmed Central ID:
  PMC6639134
• Document Type:
  Journal Article
• Funding:
  001/WHO_/World Health OrganizationInternational/ ; CC999999/Intramural CDC HHSUnited States/ ; PEPFAR/PEPFARUnited States/
• Volume:
  30
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:1ec975419ca0aab6cac8425e9e0ed41d3c4111032ea16ea04f8c9349bd5d4b28
• Download URL:
  https://stacks.cdc.gov/view/cdc/79963/cdc_79963_DS1.pdf
• File Type:
  [PDF - 279.22 KB ]