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Shift Work and Biomarkers of Subclinical Cardiovascular Disease: The BCOPS Study
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May 2019
Source: J Occup Environ Med. 61(5):391-396
[PDF-351.91 KB]
Details:
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Alternative Title:J Occup Environ Med
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Personal Author:
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Description:Objective:
To assess the association of shift work with biomarkers of subclinical cardiovascular disease and examine the moderating role of body mass index (BMI) in a police cohort.
Methods:
A cross-sectional analysis was conducted among officers who were categorized as working the day, evening, or night shift. Comparisons with inflammatory biomarkers were performed among shifts using analysis of variance/covariance and further stratified by BMI to assess potential effect modification.
Results:
Associations were observed between day and night shift workers for leukocytes, tumor necrosis factor alpha and homocysteine. After BMI stratification, higher c-reactive protein (CRP) levels were observed among evening shift workers with a BMI ≥ 30 kg/m2 versus the day shift.
Conclusions:
Future studies examining prospective changes in these markers will allow for more comprehensive evaluation of their association with shift work.
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Subject:
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Pubmed ID:30649009
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Pubmed Central ID:PMC6610651
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Document Type:
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Funding:
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