Details:

Alternative Title:
J Occup Environ Med
Personal Author:
Holst, Meghan M. ; Wirth, Michael D. ; Mnatsakanova, Anna ; Burch, James B. ; Charles, Luenda E. ; ... More +
Holst, Meghan M. ; Wirth, Michael D. ; Mnatsakanova, Anna ; Burch, James B. ; Charles, Luenda E. ; Tinney-Zara, Cathy ; Fekedulegn, Desta ; Andrew, Michael E. ; Hartley, Tara A. ; Violanti, John M. ; Less -
Description:
Objective: To assess the association of shift work with biomarkers of subclinical cardiovascular disease and examine the moderating role of body mass index (BMI) in a police cohort. Methods: A cross-sectional analysis was conducted among officers who were categorized as working the day, evening, or night shift. Comparisons with inflammatory biomarkers were performed among shifts using analysis of variance/covariance and further stratified by BMI to assess potential effect modification. Results: Associations were observed between day and night shift workers for leukocytes, tumor necrosis factor alpha and homocysteine. After BMI stratification, higher c-reactive protein (CRP) levels were observed among evening shift workers with a BMI ≥ 30 kg/m2 versus the day shift. Conclusions: Future studies examining prospective changes in these markers will allow for more comprehensive evaluation of their association with shift work.
Subject:
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Adult
Biomarkers
Body Mass Index
Cardiovascular Diseases
Cross-Sectional Studies
Humans
Male
Middle Aged
Police
Work Schedule Tolerance

Source:
J Occup Environ Med. 61(5):391-396
Pubmed ID:
30649009
Pubmed Central ID:
PMC6610651
Document Type:
Journal Article ;
Funding:
R01 OH009640/OH/NIOSH CDC HHS/United States ; R01 OH010807/OH/NIOSH CDC HHS/United States ; R01OH010807/ACL HHS/United States ;
R01 OH009640/OH/NIOSH CDC HHS/United States ; R01 OH010807/OH/NIOSH CDC HHS/United States ; R01OH010807/ACL HHS/United States ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:fb36dd9a22e53e60835a75b7ee21f9a64fbd9b83a585928ff746c7df21ca56c5
File Type:

Supporting Files

• nihms-1518217.nxml

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