CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
Trends in the Laboratory Detection of Rotavirus Before and After Implementation of Routine Rotavirus Vaccination — United States, 2000–2018
-
June 21 2019
-
-
Source: MMWR Morbidity Mortal Weekly Rep. 68(24):539-543
Details:
-
Journal Article:Morbidity and Mortality Weekly Report (MMWR)
-
Personal Author:
-
Description:Before the introduction of rotaVirus vaccine in the United States in 2006, rotaVirus infection was the leading cause of severe gastroenteritis among U.S. children (1). To evaluate the long-term impact of rotaVirus vaccination on disease prevalence and seasonality in the United States, CDC analyzed national laboratory tTesting data for rotaVirus from laboratories participating in CDC's National Respiratory and Enteric Viruses Surveillance System (NREVSS) during the prevaccine (2000-2006) and postvaccine (2007-2018) periods. Nationally, the median annual percentage of tests positive for rotaVirus declined from 25.6% (range = 25.2-29.4) in the prevaccine period to 6.1% (range = 2.6-11.1) in the postvaccine period. When compared with the prevaccine period, the postvaccine period saw declines in the annual peak in rotaVirus positivity from a median of 43.1% (range = 43.8-56.3) to a median of 14.0% (range = 4.8-27.3) and in the season duration from a median of 26 weeks (range = 23-27) to a median of 9 weeks (range = 0-18). In the postvaccine period, a biennial pattern emerged, with alternating years of low and high rotaVirus activity. Implementation of the rotaVirus vaccination program has substantially reduced prevalence of the disease and altered seasonal patterns of rotaVirus in the United States; these changes have been sustained over 11 seasons after vaccine introduction. Ongoing efforts to improve coverage and on-time vaccination (2) can help maximize the public health impact of rotaVirus vaccination.
-
Subjects:
-
Source:
-
Series:
-
DOI:
-
ISSN:0149-2195 (print);1545-861X (digital);
-
Pubmed ID:31220058
-
Pubmed Central ID:PMC6586368
-
Document Type:
-
Place as Subject:
-
Pages in Document:5 pdf pages
-
Volume:68
-
Issue:24
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type: