Mucosal Barrier Injury Laboratory-Confirmed Bloodstream Infections (MBI-LCBI): Descriptive Analysis of Data Reported to National Healthcare Safety Network (NHSN), 2013

Details

• Alternative Title:
  Infect Control Hosp Epidemiol
• Personal Author:
  Epstein, Lauren ; See, Isaac ; Edwards, Jonathan R. ; Magill, Shelley S. ; Thompson, Nicola D.
• Description:
  OBJECTIVES.
  
  To determine the impact of mucosal barrier injury laboratory-confirmed bloodstream infections (MBI-LCBIs) on central-line–associated bloodstream infection (CLABSI) rates during the first year of MBI-LCBI reporting to the National Healthcare Safety Network (NHSN)
  
  DESIGN.
  
  Descriptive analysis of 2013 NHSN data
  
  SETTING.
  
  Selected inpatient locations in acute care hospitals
  
  METHODS.
  
  A descriptive analysis of MBI-LCBI cases was performed. CLABSI rates per 1,000 central-line days were calculated with and without the inclusion of MBI-LCBIs in the subset of locations reporting ≥1 MBI-LCBI, and in all locations (regardless of MBI-LCBI reporting) to determine rate differences overall and by location type.
  
  RESULTS.
  
  From 418 locations in 252 acute care hospitals reporting ≥1 MBI-LCBIs, 3,162 CLABSIs were reported; 1,415 (44.7%) met the MBI-LCBI definition. Among these locations, removing MBI-LCBI from the CLABSI rate determination produced the greatest CLABSI rate decreases in oncology (49%) and ward locations (45%). Among all locations reporting CLABSI data, including those reporting no MBI-LCBIs, removing MBI-LCBI reduced rates by 8%. Here, the greatest decrease was in oncology locations (38% decrease); decreases in other locations ranged from 1.2% to 4.2%.
  
  CONCLUSIONS.
  
  An understanding of the potential impact of removing MBI-LCBIs from CLABSI data is needed to accurately interpret CLABSI trends over time and to inform changes to state and federal reporting programs. Whereas the MBI-LCBI definition may have a large impact on CLABSI rates in locations where patients with certain clinical conditions are cared for, the impact of MBI-LCBIs on overall CLABSI rates across inpatient locations appears to be more modest.
  
  
• Subjects:
  Bacterial Translocation Cancer Care Facilities Catheter-Related Infections Central Venous Catheters Critical Care Hematopoietic Stem Cell Transplantation Hospitals Hospitals, General Hospitals, Pediatric Humans Incidence Intestinal Mucosa Neutropenia Oncology Service, Hospital Sepsis Transplantation, Homologous

  More +
• Source:
  Infect Control Hosp Epidemiol. 37(1):2-7
• Pubmed ID:
  26456954
• Pubmed Central ID:
  PMC6557152
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Place as Subject:
  United States
• Volume:
  37
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:58ceebd0e007fde6bd65160437768f040d9785aed24ce04003315597e10a0201
• Download URL:
  https://stacks.cdc.gov/view/cdc/79237/cdc_79237_DS1.pdf
• File Type:
  [PDF - 133.54 KB ]