Burden of Pneumonia-Associated Hospitalizations

Details

• Alternative Title:
  Chest
• Personal Author:
  Hayes, Brandon H. ; Haberling, Dana L. ; Kennedy, Jordan L. ; Varma, Jay K. ; Fry, Alicia M. ; Vora, Neil M.
• Description:
  BACKGROUND: ; The epidemiology of pneumonia has likely evolved in recent years, reflecting an aging population, changes in population immunity, and socioeconomic disparities. ; METHODS: ; Using the National (Nationwide) Inpatient Sample, estimated numbers and rates of pneumonia-associated hospitalizations for 2001–2014 were calculated. A pneumonia-associated hospitalization was defined as one in which the discharge record listed a principal diagnosis of pneumonia or a secondary diagnosis of pneumonia if the principal diagnosis was respiratory failure or sepsis. ; RESULTS: ; There were an estimated 20,361,181 (SE, 95,601) pneumonia-associated hospitalizations in the United States during 2001–2014 (average annual age-adjusted pneumonia- associated hospitalization rate of 464.8 per 100,000 population 95% CI, 462.5–467.1). The average annual age-adjusted pneumonia-associated hospitalization rate decreased over the study period (P < .0001). In-hospital death occurred in 7.4% (SE, 0.03) of pneumonia-associated hospitalizations. Non-Hispanic American Indian/Alaskan Natives and non- Hispanic blacks had the highest average annual age-adjusted rates of pneumonia-associated hospitalization of all race/ethnicities at 439.2 (95% CI, 415.9–462.5) and 438.6 (95% CI, 432.5–444.7) per 100,000 population, respectively. During 2001–2014, the proportion of pneumonia-associated hospitalizations colisting an immunocompromising condition increased from 18.7% (SE, 0.2) in 2001 to 29.9% (SE, 0.2) in 2014. Total charges for pneumonia-associated hospitalizations in 2014 were over $84 billion. ; CONCLUSIONS: ; Pneumonia is a major cause of morbidity and mortality in the United States. Differences in rates and outcomes of pneumonia-associated hospitalizations between sociodemographic groups warrant further investigation. The immunocompromised population has emerged as a group experiencing a disproportionate burden of pneumonia-associated hospitalizations.
• Keywords:
  • epidemiology
  • pneumonia
  • respiratory failure
  • sepsis
  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Child
  More +
• Source:
  Chest. 153(2):427-437
• Pubmed ID:
  29017956
• Pubmed Central ID:
  PMC6556777
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/
• Volume:
  153
• Issue:
  2
• Download URL:
  https://stacks.cdc.gov/view/cdc/79133/cdc_79133_DS1.pdf
• File Type:
  [PDF - 292.56 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:0cc746d211703a5f01375cb5a5fdf5c620779487f63204112f389436d364ab86