Details:

Alternative Title:
Vaccine
Personal Author:
Suragh, Tiffany A. ; Lamprianou, Smaragda ; MacDonald, Noni E. ; Loharikar, Anagha R. ; Balakrishnan, Madhava R. ; ... More +
Suragh, Tiffany A. ; Lamprianou, Smaragda ; MacDonald, Noni E. ; Loharikar, Anagha R. ; Balakrishnan, Madhava R. ; Benes, Oleg ; Hyde, Terri B. ; McNeil, Michael M. Less -
Description:
Background:

Adverse events following immunization (AEFI) arising from anxiety have rarely been reported as a cluster(s) in the setting of a mass vaccination program. Reports of clusters of anxiety-related AEFIs are understudied. Social media and the web may be a resource for public health investigators.

Methods:

We searched Google and Facebook separately from Atlanta and Geneva to identify reports of cluster anxiety-related AEFIs. We reviewed a sample of reports summarizing year, country/setting, vaccine involved, patient symptoms, clinical management, and impact to vaccination programs.

Results:

We found 39 reports referring to 18 unique cluster events. Some reports were only found based on the geographic location from where the search was performed. The most common vaccine implicated in reports was human papillomavirus (HPV) vaccine (48.7%). The majority of reports (97.4%) involved children and vaccination programs in school settings or as part of national vaccination campaigns. Five vaccination programs were reportedly halted because of these cluster events. In this study, we identified 18 cluster events that were not published in traditional scientific peer-reviewed literature.

Conclusions:

Social media and online search engines are useful resources for identifying reports of cluster anxiety-related AEFIs and the geographic location of the researcher is an important factor to consider when conducting these studies. Solely relying upon traditional peer-reviewed journals may seriously underestimate the occurrence of such cluster events.


Subjects:
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Adolescent Adverse Drug Reaction Reporting Systems Adverse Event Anxiety Anxiety-related Reaction Article Female Humans Immunization Male Mass Vaccination Papillomavirus Vaccines Public Health Search Engine Social Media Vaccine Safety
Source:
Vaccine. 36(40):5949-5954
Pubmed ID:
30172632
Pubmed Central ID:
PMC6534132
Document Type:
Journal Article
Funding:
001/World Health Organization/International ; CC999999/Intramural CDC HHS/Intramural CDC HHS/United States
001/World Health Organization/International ; CC999999/Intramural CDC HHS/Intramural CDC HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:6fa75d26809c865fe305e35248a12e5afdc0c82afb4e87992ec7baef7d986ef9
Download URL:
https://stacks.cdc.gov/view/cdc/79025/cdc_79025_DS1.pdf
File Type:

Supporting Files

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