Details:

Alternative Title:
Diagn Microbiol Infect Dis
Personal Author:
Nash, Evelyn E. ; Henning, Tara C. ; Pham, Cau D. ; Pettus, Kevin ; Sharpe, Samera ; ... More +
Nash, Evelyn E. ; Henning, Tara C. ; Pham, Cau D. ; Pettus, Kevin ; Sharpe, Samera ; Kersh, Ellen N. Less -
Description:
Neisseria gonorrhoeae quickly develops drug resistance. Time-kill curves revealed that EDTA and TOL-463 inhibit growth similar to penicillin, ciprofloxacin, and azithromycin. Furthermore, synergistic and additive antimicrobial interactions occurred when EDTA and TOL-463 were combined with penicillin or azithromycin, respectively, suggesting that further investigations into these unconventional antimicrobials may be advantageous.
Subject:
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Anti-Bacterial Agents
Antimicrobial Resistance
Article
Boric Acid
Boric Acids
Broth Microdilution
Drug Synergism
Edetic Acid
EDTA
Microbial Sensitivity Tests
Neisseria Gonorrhoeae

Source:
Diagn Microbiol Infect Dis. 93(4):369-371
Pubmed ID:
30552033
Pubmed Central ID:
PMC6519449
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:595bf2c77c5ca25742da14fe601cca2babb6856b4554de86e5be2f67ebc5ad51
File Type:

Supporting Files

• 	nihms-1028006-f0001.gif	gif
  	nihms-1028006-f0001.jpg	jpeg
  	nihms-1028006.nxml	xml

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